Yusuf Izzettin Alihanoglu's research while affiliated with Pamukkale University and other places
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Publications (93)
Background and Aim:Chronic obesity causes adipose tissue to produce mediators that promote atherogenesis and vascular inflammation, contributing to hyperlipidemia, diabetes, hypertension, and cardiovascular disease (CVD). This study aimed to examine the relationship between body mass index (BMI) with homeostatic model assessment for insulin resista...
The accuracy of risk prediction for coronary artery disease can be improved with the use of novel molecular or genetic biomarkers. In this study, we investigated the difference of five selected microRNAs (miR or miRNA) in patients with coronary artery disease (CAD) and controls, assessed by coronary angiography. The study population consisted of 85...
Aim
This study was designed to assess the effect of patient education on the knowledge of safety and awareness about living with cardiac implantable electronic devices (CIEDs) within the context of phase I cardiac rehabilitation.
Methods
The study was conducted with 28 newly implanted CIED patients who were included in “education group (EG)”. Pati...
Correction to: Wien Klin Wochenschr 2015 https://doi.org/10.1007/s00508-015-0854-z The original version of this article unfortunately contained a mistake. The first names of Dr. Ismail Dogu Kilic were interchanged.
Background
Idiopathic hyperhidrosis (IH) is characterized by excessive and uncontrolled production of sweat, mainly localized to the soles, palms, axillae and craniofacial area. Although IH is a disease concerning the autonomic nervous system, it is not clear yet whether this dysfunction is local or systemic. Objective
To evaluate the autonomic con...
Objective:
The present study compared heart rate variability (HRV) parameters in patients with coronary artery ectasia (CAE) and coronary artery disease (CAD).
Methods:
The study population consisted of 60 consecutive patients with CAE (14 women; mean age 51.63±7.44 years), 60 consecutive patients with CA (15 women; mean age 53.67±9.31 years), a...
The clinical effect of intracoronary thrombus aspiration during percutaneous coronary intervention in patients with unstable angina pectoris is unknown. In this study, we aimed to assess how thrombus aspiration during percutaneous coronary intervention affects in-hospital and 30-month mortality and complications in patients with unstable angina pec...
In patients with coronary artery disease (CAD), though aspirin inhibits platelet activation and reduces atherothrombotic complications, it does not always sufficiently inhibit platelet function, thereby causing a clinical situation known as aspirin resistance. As hyperuricemia activates platelet turnover, aspirin resistance may be specifically indu...
We have read the original article 'Evaluation of the Variations in the Aortic Arch and its Branches by Multi-sectional Computed Tomography' by Boyacı at al. [1] in your journal published in the January 2015 with interest. We congratulate the authors for this article. As known, as a standard left aortic arch and descending thoracic aorta is observed...
We have read the original article 'Evaluation of the Variations in the Aortic Arch and its Branches by Multi-sectional Computed Tomography' by Boyacı at al. [1] in your journal published in the January 2015 with interest. We congratulate the authors for this article. As known, as a standard left aortic arch and descending thoracic aorta is observed...
An assessment of the clinical significance of aortic arc variations
Background:
Metabolic syndrome (MS) refers to a group of cardiovascular risk factors associated with endothelial dysfunction and impaired coronary blood flow (CBF). Homocysteine (Hcy) is another risk factor for the development of insulin resistance and endothelial dysfunction. However, the relationship between Hcy levels and CBF in patients with M...
Background:
We aimed to investigate the circadian rhythm on left ventricular (LV) function and infarct size, according to the onset of ST elevation myocardial infarction (STEMI), with echocardiography in patients with first STEMI successfully revascularised with primary percutaneous coronary intervention (PCI).
Methods:
We conducted a retrospect...
Objective: Atrial functions are relatively suppressed in heart failure (HF). We aimed to investigate the associations of intra- and inter-atrial electromechanical conduction delay (EMCD) with functional class and mortality over a 12-month follow-up period.
Methods: The study included 65 patients with systolic HF and 65 healthy subjects with normal...
Transcatheter aortic valve implantation is preferred to treat high surgical risk patients with severe aort stenosis. Wrapping of a pig tail catheter with device struts during transcatheter aortic valve implantation is a very rare complication. In this report, we present the images and videos of an attempt of retrieval of an aortic valve wrapped wit...
The aim of this study is to investigate the presence of limitations in the shoulder range of motion (ROM) or the loss of upper extremity function on the affected side in patients with cardiac implantable electronic devices (CIEDs) with respect to the implantation time. Forty-nine patients (30 men and 19 women), mean age 64.84±11.18 years, who had b...
VCAM-1 and ICAM-1 are two important members of the immunoglobulin gene superfamily of adhesion molecules, and their potential role as biomarkers of diagnosis, severity and prognosis of cardiovascular disease has been investigated in a number of clinical studies. The aim of the present study was to determine the relationship between circulating ICAM...
BACKGROUND:Heart rate (HR) reduction is associated with improved outcomes in patients with heart failure (HF) and biomarkers can be valuable and diagnostic tool in HF management.The primary aim of our study was to evaluate the short-term (6 months) effect of ivabradine on NT-proBNP, CA-125, and cystatin-C values in systolic HF outpatients and secon...
Background:
The aim of this study was to retrospectively evaluate the clinical and electrophysiological characteristics of elderly patients with typical atrioventricular nodal reentrant tachycardia (AVNRT), and to assess the acute safety and efficacy of slow-pathway radiofrequency (RF) ablation in this specific group of patients.
Methods and resu...
Obesity alters endocrine and metabolic functions of adipose tissue and has been recognized as a chronic inflammatory disease, which in turn may contribute to the development of insulin resistance, type 2 diabetes, obesity-associated vasculopathy and cardiovascular disease. The pathogenesis of obesity involves many regulatory pathways including tran...
The aim of this study was to evaluate and compare systolic blood pressure recovery and heart rate recovery (HRR) values obtained at various time intervals after maximal graded exercise treadmill testing between patients with metabolic syndrome (MS) and the controls without MS. To our knowledge, this is the first study indicating systolic blood pres...
We read the case report of Hakan Güllü et al. entitled 'Aortic Root Rupture During Trans-catheter Aortic Valve Replacement Operation: " Case Report " , which was published in January 2015 with interest. We congratulate the authors (1). Aortic root rupture (ARR) is a severe complication of Trans-catheter Aortic Valve Replacement (TAVR) or Trans-cath...
Isolated non-compaction of the left ventricular myocardium (INVM) was first described in 1984 as an unclassified cardiomyopathy, not being dilated, hypertrophic or restrictive. It is assumed to occur as a result of an arrest in endomyocardial morphogenesis during normal development of the heart. The disease is characterised by heart failure due to...
Coronary artery fistulas are the second most frequently seen coronary anomaly following abnormalities of coronary artery origin and distribution. A coronary fistula is defined as a direct communication between a coronary artery and any cardiac chamber or vessel. Treatment options include percutaneous embolization and surgical intervention. Herein,...
Radiofrequency (RF) ablation of accessory bypass tracts associated with the Wolff-Parkinson-White (WPW) syndrome has become the treatment of choice for many arrhythmias. Complications are unusual and acute coronary artery occlusion is very rare. We here present a 38-year-old male patient with an acute occlusion of proximal left anterior descending...
Radiofrequency (RF) ablation of accessory bypass tracts associated with the Wolff -Parkinson-White (WPW) syndrome has become the treatment of choice for many arrhythmias. Complications are unusual and acute coronary artery occlusion is very rare. We here present a 38-year-old male patient with an acute occlusion of proximal left anterior descending...
Myocardial bridging (MB) is defined as the intramural course of a major epicardial coronary artery, and is mostly confined to the left ventricle and the left anterior descending coronary artery (LAD). MB is a common congenital abnormality of a coronary artery, and is usually thought to be a benign anatomical variant. Although rare, previous studies...
The aim of this study is to retrospectively investigate clinical and electrophysiologic characteristics of typical AVNRT with relatively slow tachycardia rates below the average value compared to faster ones, in patients without structural heart disease.
The present study retrospectively included a total of 1,150 patients receiving successful slow-...
Direct communication of the right pulmonary artery and the left atrium is an extremely rare congenital malformation of the pulmonary vasculature. A 41-year-old woman with a history of cyanosis since childhood presented with mild exertional dyspnea. On physical examination, she had central cyanosis, clubbing of the fingers, and an upright position c...
Aim of the study: According to the literature, many surgeons aim to obtain complete revascularization during coronary artery surgery. This becomes an issue when the left anterior descending (LAD) artery is diffusely diseased. This study presents the results of revascularization surgery of LAD arteries with multiple stenoses and the subsequent angio...
Primary tumors of the heart are rare. Approximately 75 % of primary tumors are benign and 50 % of benign tumors are myxomas. Although traditionally less frequently reported, papillary fibroelastoma is increasingly recognized [1]. Other benign tumors of the heart include rhabdomyomas, fibromas, fibroelastomas, and lipomas. Lipomas are well-encapsula...
Coronary artery perforation (CAP) is a rare but feared complication of percutaneous coronary intervention. With the advent of new devices and technologies, interventionalists attempt more complex lesions, including more calcified or tortuous vessels and chronic total occlusions, which increases the incidence of CAP. A short literature review, in ad...
The aim of this study was to investigate impact of central blood pressure (BP) levels and sex on the difference between central and upper arm oscillometric BP values. Oscillometric arterial BP measurements of 675 patients were simultaneously compared with values measured from the ascending aorta. The patients were divided into 3 groups according to...
Strain and strain rate imaging is currently the most popular echocardiographic technique that reveals subclinical myocardial damage. There are currently no available data on this imaging method with regard to assessing right ventricular involvement in anterior myocardial infarction. Therefore, we aimed to evaluate right ventricular regional functio...
The aim of this study is to evaluate heart rate recovery and association between coronary flow rate and heart rate recovery in patients with metabolic syndrome who had morphologically normal coronary angiogram.
Study population included 43 patients with metabolic syndrome and 37 control subjects without metabolic syndrome. All patients were selecte...
Perikardiyal mezotelyal inklüzyon kistleri, aberran yer-leşimli olan ve çölomik boşluktan köken alan genellikle benign toraks içi lezyonlardır. Asemptomatik olmalarına karşın, büyük boyutlara ulaşıp komşu yapıları enfekte edebilir veya bu yapılara bası yapabilir. Tanı sıklıkla göğüs röntgeni ile tesadüfen konur. Bu yazıda, nefes darlığı ve bacaklar...
Many drugs are known to cause lengthening of the QT interval. Ibandronic acid is a frequently used agent in the treatment of osteoporosis and is known to cause prolongation of the QT interval due to hypocalcaemia. However, no cases of long QT syndrome associated with ventricular tachycardia (VT) with a serum calcium level within the normal limits h...
Internal mammary artery (IMA) grafts have been shown to be superior to saphenous vein grafts in terms of rare atherosclerotic involvement, biochemical and physical qualities, and long-term patency rates. The IMA originates from the subclavian artery, just distal to the vertebral artery, and an occlusion or a hemodynamically significant stenosis pro...
Hypertension is the most common and challenging medical problem during pregnancy. It complicates up to 15% of pregnancies and is a leading cause of maternal and fetal morbidity and mortality. Hypertension during pregnancy is classified as preeclampsia–eclampsia, gestational hypertension, chronic hypertension and superimposition of preeclampsia on c...
A coronary artery fistula consists of a communication between a coronary artery and a cardiac chamber, a great artery or the vena cava. It is the most common congenital anomaly that can affect coronary perfusion. However, coronary fistulas to one of the cardiac chambers and coexisting apical myocardial hypertophy are infrequent anomalies, and usual...
Ring annuloplasty is the standard treatment of ischemic mitral regurgitation (MR), however, it has been associated with some drawbacks. It abolishes normal annular dynamics and freezes the posterior leaflet. In the present study, we evaluated Paneth suture annuloplasty in chronic ischemic MR and both early and mid-term outcomes of the technique on...
We aimed to investigate whether coronary sinus (CS) dilatation develops in patients with mitral stenosis (MS) and to demonstrate its relationship with the global myocardial performance of the right ventricle (RV).
We enrolled 34 patients with MS who underwent echocardiography after exhibiting typical symptoms (31 female; mean age 41 ± 12 years) and...
Acute coronary syndromes (ACS) are one of the leading causes of death and morbidity in industrialized countries. Typical presentation includes acute chest pain, cardiac troponin elevation and possibly associated electrocardiogram abnormalities. In great majority of the cases, myocardial infarction (MI) is due to atherosclerosis, usually with plaque...
It is known that there is an interaction between oral contraceptive pills and the cardiovascular-hemostatic system. In this case report, we discuss a 29-year-old female patient, who had been taking oral contraceptive drugs, who was admitted to the emergency department with chest pain. Acute anterior myocardial infarction was diagnosed.
Objectives:
The aim of this study was to use echocardiographic techniques to determine the possible cardiotoxic effects of low molecular weight tyrosine-kinase inhibitors (TKI) in patients receiving the therapy for the first time.
Study design:
Thirty patients (17 females; 13 males; mean age 49±16; range 22 to 76 years) who met the exclusion cri...
Objectives:
This study investigated the appropriateness of treatment for patients admitted with ST-segment elevation myocardial infarction (STEMI) according to the current guidelines. We also aimed to determine in-patient and out-patient factors affecting optimal reperfusion therapy.
Study design:
The reperfusion therapy of 176 patients with STE...
Aim:
Inflammation is a critical participant in mediating all stages of cardiovascular disease. Studies related with chitotriosidase that was recently found to be relevant to arterial inflammation. In this study we evaluated activity of serum chitotriosidase in acute coronary syndrome patients and its relationship with cardiovascular events, cardia...
The aim of this study was to investigate the effects of spironolactone on left ventricular (LV) remodeling in patients with preserved LV function following acute myocardial infarction (AMI).
Successfully revascularized patients (n = 186) with acute ST elevation MI (STEMI) were included in the study. Patients were randomly divided into three groups,...
Neurofibromatosis is an autosomal dominant multi-system genetic disorder. Extra-cardiac vascular manifestations of neurofibromatosis have been previously described in many reports. However, coronary arterial involvements have been rarely described. A 17-year-old girl with neurofibromatosis presented to our institute with subacute myocardial infarct...
A 76-year-old male patient diagnosed with acute, massive pulmonary embolism due to deep vein thrombosis of a lower extremity developed significant cardiovascular and respiratory instability. Subsequently, streptokinase infusion was administered over two hours. Spiral computed tomography was performed due to the persistent hemodynamic instability fo...
Objectives: This study investigated the appropriateness of treatment for patients admitted with ST-segment elevation myocardial infarction (STEMI) according to the current guidelines. We also aimed to determine in-patient and out-patient factors affecting optimal re perfusion therapy. Study design: The reperfusion therapy of 176 patients with STEMI...
Although, there has been great improvement on the diagnosis and early treatment of acute coronary syndromes, especially in terms of myocardial damage biochemical markers, we do not have a specific marker yet, for using the diagnosis of stable coronary artery disease (CAD). This study aimed to evaluate the relationship between CAD and the changes of...
In this study, our aim was to evaluate the effect of a higher dose of atorvastatin on the recurrence rate of atrial fibrillation (AF) after electrical cardioversion (EC) in addition to antiarrhythmic therapy.
48 patients with persistent AF were included in this study. The patients were randomized to an atorvastatin 40-mg treatment group and a contr...
Aim: This study was designed to compare the fasting ghrelin, leptin and resistin levels between metabolic syndrome (MS) patients with healthy controls. Method: This trial was performed on 21 patients with MS (7 men; mean age, 44±4 years) and 17 healthy controls (8 men; mean age, 43±3 years). Diagnosis of MS was defined based on National Cholesterol...
zet Torasik aorta hastalıkları mortalite ve morbiditesi yüksek olan gruptur. Semptomların başlangıcından itibaren hızlı tanı ve erken müdahale gerektirir. Bu olgu sunumunda TEVAR uyguladığımız kronik böbrek yetersizliği nedeniyle hemodiyaliz uygulanan, antihipertansif tedavi alan ve acil servise şiddetli sırt ağrısıyla başvuran Tip B aort diseksiyo...
Contrast-induced nephropathy (CIN) is a leading cause of acute renal failure and affects mortality and morbidity. We investigated the efficacy of prophylactic intravenous (IV) N-acetylcysteine (NAC) and hydration for the prevention of CIN in patients with mild to moderate renal dysfunction who are undergoing coronary angiography and/or percutaneous...
Wide pulse pressure (PP) affects the accuracy of oscillometric blood pressure measurements (OBPM): however, the degree of this impact on different patient groups with wide PPs is unclear. This study will investigate the accuracy of OBPM in achieving target BP and PP in isolated systolic hypertension (ISH) group compared with mixed hypertension (MHT...
Many atherothrombotic complications are associated with coronary angiography. Spinal cord embolism with high morbidity and mortality is one of these complications.
Case report.
A 65-year-old woman was admitted to the hospital with acute myocardial infarction. Immediately after coronary angiography, she complained of paresthesia and paraparesis of h...
Both metabolic syndrome (MetS) and nondipping status (insufficient reduction in nocturnal blood pressure) have been linked with target organ damage. We evaluated the effect of nondipping status on target organ damage in subjects with MetS.
Eighty-two patients diagnosed as having MetS were divided into two groups according to the findings of 24-hour...
The purpose of this study was to examine the effects of exercise on maximum QTc interval (QTcmax) and QTc dispersion (QTcd) in diabetic patients without clinically evident heart disease.
Seventy-six diabetic patients who had no coronary artery disease or hypertension (group I; mean age 48 +/- 9 years old) and 40 healthy volunteers (group II; mean a...
Citations
... Other studies have reported elevated expression of miR-21-5p in mononuclear cells and also plasma of patients having CAD [97,98]. There is a suspicion that the aforementioned miR may be involved via the regulation of inflammatory cytokines through a signaling pathway (JNK) [99] or the phosphatidylinositol 3-hydroxykinase [PI3K]/protein kinase B [AKT] pathway [100]. This could lead to the proliferation and migration of vascular smooth muscle cells, which in turn could lead to more severe vasoconstriction and worsening of CAD [101]. ...
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... The findings of this present study do support the use of patient education as a comprehensive tool to aid in lowering anxiety and depression among people with intracardiac devices. A single-center prospective, single-blinded study was carried out by experts at the cardiology department of the University of Pamukkale Hospital in 2018 [20] . This study was designed to assess the effect of patient education on knowledge of safety and awareness regarding living with cardiac implantable electronic devices (CIEDs) throughout phase I cardiac rehabilitation. ...
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... A total of 450 articles (269 PubMed and 181 Google Scholar) were found, and a reference search of the included citations added 10 more studies. Among these, 100 studies were excluded as duplicates, and 315 studies were also excluded based on abstracts (283 not related to the aim of the meta-analysis, 20 based on cadaveric studies, 6 based on not random pathological population [6,10,14,17,25,42], 2 letters to the Editor [3,15], 2 not adult population [12,44], 1 case report [21], and 1 non-human study [22]). Subsequently, 45 full-text articles were analyzed for eligibility. ...
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... Both the SBP increase at exercise and the decrease at recovery predicted the HRR increase in response to the PARA2010 intervention in RA. Previous studies have established a relationship between HRR and SBP, but provided contradictory conclusions if SBP changes during exercise are a consequence or cause of the observed HRR (38)(39)(40)(41)(42). In this study, SBP recovery followed the pattern of HRR and increased in the first year. ...
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... For lager PDAs, the Amplatzer mVSD occluder is an effective choice yet, particularly for those complicated with severe pulmonary arterial hypertension. [7][8][9][10][11] The mVSD occluder manufactured in China is similar to the Amplatzer occluder. We choose the mVSD occluder because the duct in our case was large and the pulmonary pressure was high. ...
... A malpositioned LMCA stent can be treated either surgically or conservatively. Gunes et al. [4] presented a case of a successful removal of a malpositioned right coronary artery stent with a guidewire. Also, in two cases presented by Sechi et al., [3] malpositioned and thrombosed LMCA stents were surgically treated. ...
... [24] In our study there was no significant difference between group 1 and group 2 regards cerebrovascular stroke incidence at 30 days follow up, and this is in agreement with the TASTE trial and Göran K et. al [25], also Tung et al found the incidence rates of stroke during the index hospitalization were 1.1 and 2.34 per 100 person-months in the thrombectomy and PCI alone groups, respectively (SHR: 0.59; 95% CI: 0. 22 [26] found similar data in their study during the hospital stay but, stroke was higher in the group that was managed with TA at 30 months follow up. In our study all stroke cases occurred within the first weak, four of them occurred within the first 48 days while the 5th case occurred on the 6th day, and this was in agreement with Jeffrey T et.al. ...
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... цию коронарной артерии, вазоспазм, артериальный тромбоз на фоне тромбофилии [1]. ...
... p = 0.041) and LDL-C and predicted an unfavourable stroke outcome at 90 days [32]. In a study in Turkey, patients with stable angina with aspirin resistance had significantly higher WBC count, neutrophil counts, neutrophil-to-lymphocyte ratios, serum uric acid (SUA) levels, high-sensitivity C-reactive protein levels, and fasting blood glucose levels and high SUA levels were an independent predictor of aspirin resistance after multivariate analysis, with a cut-off value of 6.45 mg/dl for SUA to predict aspirin resistance with 79% sensitivity and 65% specificity on ROC analysis [33]. In another study, in patients with acute coronary syndromes, the anti-aggregant effect of aspirin assessed by PFA-100 closure times with ADP (PFA/ADP) and epinephrine (PFA/EPI) were modulated not only by the direct action on platelets, but also by erythrocyte deformability and WBC count [34]. ...
... Recently, Sood et al. (19) reported systemic amyloidosis can be diagnosed after carpal tunnel release procedure and heart failure increased 4,68-fold the risk of systemic amyloidosis diagnosis after carpal tunnel release. Heart failure is a risk factor for atrial enlargement and AF (20). Also, heart failure associated with prolonged atrial EMD (20). ...
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