Yun Huang's research while affiliated with Zhejiang University and other places

Publications (4)

Article
Three novel SEK15-derived polyketides, strepolyketides A-C (1-3), and the known SEK15 (4) were identified from Streptomyces sp. HN2A53. Their structures were established by comprehensive 1D and 2D NMR spectroscopic analysis and HRESIMS data. Compounds 2-3 were the unique dimers of SEK15. Biological evaluation of these compounds showed that compound...
Article
Nitricquinomycins A-C (1∼3), three uncommon naphthopyrrolediones, together with one new compound (4), were isolated from the modified rice solid fermentation of the marine-derived Streptomyces sp. ZS-A45, an actinobacterium isolated from the marine sediments collected from Zhoushan island. Their structures were elucidated on the basis of MS, NMR sp...
Article
A new medermycin analog (1) was isolated from the marine-derived actinomycetes Streptomyces sp. ZS-A45. The structure elucidation of compound 1 was determined by the HRESIMS and extensive NMR analysis. And compound 1 exhibited significant cytotoxicity against PC3 cell lines with IC50 values of 0.81 ± 0.42 μm.

Citations

... To harness bioactive compounds from marine-derived microorganisms [4][5][6][7] , A strain identified as Streptomyces sp. A31 was isolated from a marine sediment sample collected on Zhoushan Island. ...
... Many other antifungal compounds produced by Streptomyces spp. have been isolated, including nitricquinomycins A-C (C154-C156) [99]; rocheicoside A (C171) [103]; 28-N-methylikaguramycin (C176), isoikarugamycin (C177), and ikarugamycin (C178) [106]; caboxamycin (C190) [115]; and piperazimycin B (C191) [116]. Besides Streptomyces, other bacteria have also been explored. ...