Yifan Liu's research while affiliated with Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine and other places
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Publications (19)
Background
With increasing detection of small renal masses and accumulating evidence that nephron sparing surgery (NSS) could achieve oncological equivalence and functional superiority compared with radical nephrectomy (RN), NSS has become first‐line therapy for some patients with localized renal masses.
Objective
This study aims to review the pub...
Background
Fostering empathy has been continuously emphasized in the global medical education. Empathy is crucial to enhance patient-physician relationships, and is associated with medical students’ academic and clinical performance. However, empathy level of medical students in China and related influencing factors are not clear.
Methods
This was...
Background
Prostate cancer (PCa) is one of the most threatening health problems for the elderly males. However, our understanding of the disease has been limited by the research technology for a long time. Recently, the maturity of sequencing technology and omics studies has been accelerating the studies of PCa, establishing themselves as an essent...
Background
Kidney renal papillary cell carcinoma (KIRP) is the second most prevalent malignant cancer originating from the renal epithelium. Nowadays, cancer stem cells and stemness-related genes (SRGs) are revealed to play important roles in the carcinogenesis and metastasis of various tumors. Consequently, we aim to investigate the underlying mec...
Background
Malignant mesothelioma is a type of infrequent tumor that is substantially related to asbestos exposure and has a terrible prognosis. We tried to produce a fibroblast differentiation-related gene set for creating a novel classification and prognostic prediction model of MESO.
Method
Three databases, including NCBI-GEO, TCGA, and MET-500...
Gut microbiota can regulate many physiological processes within gastrointestinal tract and other distal sites. Dysbiosis may not only influence chronic diseases like the inflammatory bowel disease (IBD), metabolic disease, tumor and its therapeutic efficacy, but also deteriorate acute injuries. This article aims to review the documents in this fiel...
Background:
Bladder urothelial carcinoma (BLCA) is a malignancy with a high incidence worldwide. One-third of patients may experience aggressive progression later on, and 70% of patients who have undergone surgical intervention will still suffer from metastasis.
Materials and methods:
RNA sequencing profiles of BLCA samples were obtained from Th...
Background
Renal cell carcinoma (RCC) is one of themost prevalent and lethal malignancies globally. Enhancer RNAs (eRNAs) serve as potential diagnostic and prognostic markers andpotential therapeutic targets for cancer. This study aim to explore the roles of enhancer RNAs (eRNAs) in renal cell carcinoma (RCC) metastasis.
Methods
RNA-seq data of RC...
Background
Anoctamin family (Transmembrane Protein 16), has gained growing attention for generating exosome and ectosome to mediate cancer cell communication in the process of phospholipid scrambling. However, former studies only focused on one narrow process in a single cancer. Instead, we designed a multidimensional study to comprehensively inves...
Background
Kidney renal papillary cell carcinoma (KIRP) is the second most prevalent malignant cancer originating from the renal epithelium. Nowadays, cancer stem cells (CSC) and stemness-related genes (SRGs) are constantly revealed to play important roles in carcinogenesis and metastasis of various tumors. In the present study, we aim to investiga...
Background:
Diabetic foot ulcers (DFUs) are one of the most popular and severe complications of diabetes. The persistent non-healing of DFUs may eventually contribute to severe complications such as amputation, which presents patients with significant physical and psychological challenges. Fibroblasts are critical cells in wound healing and perfor...
Background: The signal transducer and activator of transcription (STAT) gene family have been widely found to regulate cell proliferation, differentiation, apoptosis, and angiogenesis through complex signaling pathways, and thus impacting tumor formation and development in different types of tumor. However, the roles of STATs on prognostic predicti...
Background
Rheumatism covers a wide range of diseases with complex clinical manifestations and places a tremendous burden on humans. For many years, our understanding of rheumatism was seriously hindered by technology constraints. However, the increasing application and rapid advancement of sequencing technology in the past decades have enabled us...
Background
Rheumatoid Diseases (RDs) are a group of systemic auto-immune diseases that are characterized by chronic synovitis, and fibroblast-like synoviocytes (FLSs) play an important role in the occurrence and progression of synovitis. Our study is the first to adopt bibliometric analysis to identify the global scientific production and visualize...
Introduction
Over the last several decades, the gut microbiota has been implicated in the formation and stabilization of health, as well as the development of disease. With basic and clinical experiments, scholars are gradually understanding the important role of gut microbiota in trauma, which may offer novel ideas of treatment for trauma patients...
Background
Rheumatic diseases (RD) are a group of multi-system inflammatory autoimmune diseases whose causes are still under study. In the past few decades, researchers have found traces of the association between rheumatic diseases and intestinal microbiota, which can partially explain the pathogenesis of rheumatic diseases. We aimed to describe t...
Background
Spinal cord injury (SCI) is a severe disease with motor and sensory function being destroyed, which leads to a poor prognosis and a serious financial burden. It is urgent to figure out the molecular and pathological mechanisms of SCI to develop feasible therapeutic strategies. This article aims to review documents focused on gene express...
Background: The molecular mechanisms of EWS-FLI-mediating target genes and downstream pathways may provide a new way in the targeted therapy of Ewing sarcoma. Meanwhile, enhancers transcript non-coding RNAs, known as enhancer RNAs (eRNAs), which may serve as potential diagnosis markers and therapeutic targets in Ewing sarcoma.
Materials and methods...
Background:
We planned to uncover the cancer stemness-related genes (SRGs) in prostate cancer (PCa) and its underlying mechanism in PCa metastasis.
Methods:
We acquired the RNA-seq data of 406 patients with PCa from the TCGA database. Based on the mRNA stemness index (mRNAsi) calculated by one-class logistic regression (OCLR) algorithm, SRGs in...
Citations
... 13 Through analyzing authors, journals, institutions, countries and keywords, the performance analysis, evolution process, and research hotspots of a field can be obtained. 14 Bibliometrics has also been applied in research in many aspects including gut microbiota, sequencing, and various diseases, [15][16][17][18] which all showed great impacts. As a result, we hoped to explore the developing processes and research hotspots in the kidney neoplasm and NSS field through bibliometric analysis and literature review. ...
... 12 In addition, bibliometric tools such as CiteSpace, 13 VoSviewer, 14 and the R package "bibliometrix" 15 have been used for visual literature analysis, as they are more intuitive for interpreting a large amount of information and mining research hotspots. Bibliometrics has been widely used in the fields of cancer, 16 knee osteoarthritis, 17 cardiovascular diseases, 18 and rheumatic diseases, 19 but no bibliometric method has been used to research PCD in OP. Therefore, to fill this knowledge gap, this study used bibliometrics and visual analytics to summarize the academic research on PCD in OP over the last two decades in the Web of Science database. ...
... 13 Through analyzing authors, journals, institutions, countries and keywords, the performance analysis, evolution process, and research hotspots of a field can be obtained. 14 Bibliometrics has also been applied in research in many aspects including gut microbiota, sequencing, and various diseases, [15][16][17][18] which all showed great impacts. As a result, we hoped to explore the developing processes and research hotspots in the kidney neoplasm and NSS field through bibliometric analysis and literature review. ...
... 13 Through analyzing authors, journals, institutions, countries and keywords, the performance analysis, evolution process, and research hotspots of a field can be obtained. 14 Bibliometrics has also been applied in research in many aspects including gut microbiota, sequencing, and various diseases, [15][16][17][18] which all showed great impacts. As a result, we hoped to explore the developing processes and research hotspots in the kidney neoplasm and NSS field through bibliometric analysis and literature review. ...
... Bibliometrics analyzes published information (such as journal articles, books) and its associated metadata (such as citations, abstracts, and keywords), in order to characterize or demonstrate correlations between published works (11). A number of bibliometric studies have been conducted in the field of rheumatism, spinal cord injury, COVID-19, etc. (12)(13)(14). However, there has not been a comprehensive bibliometric study concerned with sequencing and omics studies in PCa. ...
... 32 Expression of PHLDA1 could decrease the infiltrating of T cells. 33 Therefore, PHLDA1 is a unique maker gene of Tregs and could be a promising target for immunotherapy. ...
... The messenger RNA (mRNA) expression-based stemness index (mRNAsi) is used to evaluate the unique characteristics of CSCs and to assess tumor development (9). There is mounting evidence to support the existence of CSCs in lung adenocarcinoma (10), breast cancer (11), colorectal cancer (12), and prostate cancer (13), as well as their roles in metastasis, drug resistance, and cancer adaptation to changing microenvironments. For instance, single-cell transcriptome analysis revealed the landscape of intra-tumoral heterogeneity and stemness-related subpopulations of liver cancer cells (14). ...
