Yi-Ge Wu's scientific contributions
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It was automatically created by ResearchGate to create a record of this author's body of work. We create such pages to advance our goal of creating and maintaining the most comprehensive scientific repository possible. In doing so, we process publicly available (personal) data relating to the author as a member of the scientific community.
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Publication (1)
Microglia are resident immune cells in the central nervous system. During the pathogenesis of Alzheimer's disease, stimulatory factors continuously act on the microglia causing abnormal activation and unbalanced phenotypic changes; these events have become a significant and promising area of research. In this review, we summarize the effects of mic...
Citations
... As intrinsic immune cells in the central nervous system, microglia play a role in surveillance and clearance of damaged or injured tissue, and are crucial for maintaining the homeostasis of the neural environment (Wu et al., 2023). Whether microglia exert beneficial or detrimental effects depends on various factors such as the type of stimulus and the duration of the impact, as transient activation of microglia usually has neuroprotective effects in NDs, but chronic or prolonged responsiveness of these cells can induce activation and lead to neuronal damage (Porro et al., 2021). ...