Ye Kang's research while affiliated with Hunan Normal University and other places
What is this page?
This page lists the scientific contributions of an author, who either does not have a ResearchGate profile, or has not yet added these contributions to their profile.
It was automatically created by ResearchGate to create a record of this author's body of work. We create such pages to advance our goal of creating and maintaining the most comprehensive scientific repository possible. In doing so, we process publicly available (personal) data relating to the author as a member of the scientific community.
If you're a ResearchGate member, you can follow this page to keep up with this author's work.
If you are this author, and you don't want us to display this page anymore, please let us know.
It was automatically created by ResearchGate to create a record of this author's body of work. We create such pages to advance our goal of creating and maintaining the most comprehensive scientific repository possible. In doing so, we process publicly available (personal) data relating to the author as a member of the scientific community.
If you're a ResearchGate member, you can follow this page to keep up with this author's work.
If you are this author, and you don't want us to display this page anymore, please let us know.
Publications (9)
Background
To illustrate the transperitoneal laparoscopic unroofing (TLU) and compare the efficacy and safety of TLU to fenestration under seminal vesiculoscopy (FUSV) in treating symptomatic seminal vesicle cyst (SVC).
Methods
We retrospectively reviewed all patients with symptomatic SVC who underwent TLU or FUSV between 2008 and 2020 at 3 instit...
DNA methylation plays a pivotal role in the progression of renal fibrosis. Methyl-CpG-binding domain protein 2 (MBD2), a protein reader of methylation, is involved in the development of acute kidney injury (AKI) caused by vancomycin. However, the role and mechanism of action of MBD2 in renal remain unclear. In this study, MBD2 mediated extracellula...
Recent studies reported that Methyl-CpG–binding domain protein 2 (MBD2) promoted M2 macrophages accumulation to increase bleomycin-induced pulmonary fibrosis. However, the role and mechanism of action of MBD2 in macrophages differentiation and renal fibrosis remain largely unknown. In the current study, MBD2 not only promoted the differentiation of...
Background:
To illustrate the bladder autoaugmentation by transurethral vesicomyotomy (BATV) and compare the efficacy and safety of BATV to bladder hydrodistention (BH) for managing ketamine cystitis (KC).
Methods:
We retrospectively analyzed clinical data for 53 patients with KC who received surgical intervention between 2014 and 2019 at our ho...
Bladder cancer (BCa) is an aggressive malignancy because of its distant metastasis and high recurrence rate. Circular RNAs (circRNAs) exert critical regulatory functions in cancer progression. However, the expression patterns and roles of circRNAs in BCa have not been well investigated. In this study, we first screened circRNA expression profiles u...
Background:
Bladder cancer is one of the most frequent urologic tumours in the world. MicroRNA-200c (miR-200c) has been considered a regulator of tumour angiogenesis. Akt2/mTOR was considered a regulator of vascular endothelial growth factor (VEGF) and hypoxia-inducible factor 1α (HIF-1α). However, the mechanism by which miR-200c regulates bladder...
Background:
Renal fibrosis, a common pathological outcome of chronic kidney disease (CKD), is characterized by extracellular matrix (ECM) accumulation, damage to the tubular epithelium, and the proliferation and activation of fibroblasts. SnoN, a TGF-β1/Smad transcriptional co-suppressor, is downregulated in obstructive nephropathy. However, the r...
Androgens and androgen receptors are vital factors involved in prostate cancer progression, and androgen ablation therapies are commonly employed to treat advanced prostate cancer. Previously, FUsed in Sarcoma (FUS) was identified as an AR-interacting protein that enhances AR transcriptional activity. In the present study, we attempted to identify...
Objective:
To identify risk factors for early complications in patients after robot-assisted laparoscopic radical cystectomy (RARC) and a standardized reporting model to predict complications precisely and recommend reasonable prophylaxis.
Methods: A total of 90 patients with bladder cancer, who underwent RARC in the Second Xiangya Hospital and t...
Citations
... During keloid formation, EGR1 responds to TGF-β and promotes ROS production by activating NADPH oxidase 4 (NOX4) [39]. Furthermore, EGR1 overexpression triggers ECM catabolism in specific embryonic fibroblasts in mice [40]. Our study also confirmed that EGR1 is significantly increased in oxidative stress-induced degenerative NPCs. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/890754843033600-1589383912045_Q64/Jian-Pan-20.jpg)
... A retrospective clinical study on coronary atherosclerosis demonstrated that G0S2 expression in peripheral blood leukocytes is an independent risk factor for AMI in patients with stable CAD [51]. In addition, the overexpression of G0S2 can promote the transition of M2 macrophages to M1 macrophages, exacerbating inflammation progression in the kidney and accelerating renal fibrosis [52]. In a recently published study, G0S2 was highly correlated with AAA [53]. ...
... Therefore, miR-200a-3p could regulate MET and indirectly act on the corresponding ZEB1 targets to promote the invasion and metastasis of endometrial cancer. A corresponding mechanistic axis could exist between miR-200a-3p and ZEB1 or competitively bind with other targets [32,33] to regulate the progression of malignancy. Our research group will explore the specific mechanism producing this effect further. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/976986377818119-1609943112596_Q64/Haiqing-He-3.jpg)
... Thus, we wondered whether miR-200c-3p could target ECs to down-regulate Flt1 and thereby promote ATII cell transdifferentiation in a paracrine manner. This idea is consistent with recent studies describing a role for miR-200c in cancerassociated angiogenesis [26][27][28], and with other studies highlighting the role of angiogenesis during alveolar regeneration [8,9,29]. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/11431281142744370-1681196010207_Q64/Ran-Xu-28.jpg)
... Numerous miRNAs have been identified in acute or chronic kidney diseases, such as miR-21-5p, which strongly correlates with fibrosis progression [26]. TGF-β also induces pro-fibrotic miR-130 in human renal proximal tubular epithelial cells [27] and miR-199a in the kidneys of hypertensive rats as well [28]. The miR-199a forms a pre-miR that undergoes RNA processing to yield miR-199a-5p and miR-199a-3p. ...
... AR-mediated androgen actions play a role in regulating female fertility and follicle health, development and ovulation (Walters et al., 2019). Besides, in kidney cancer, bladder cancer and prostate cancer, AR has been identified to be critical to multiple tumors' development and progression via promoting cell proliferation and suppressing apoptosis, and especially in prostate cancer, AR activity was suppressed by miR-320a Pak et al., 2019;Zheng et al., 2020), which also was observed in our target network. Similarly, a series of studies have shown that the miR-320a inhibits tumor cell proliferation by targeting FoxM1. ...
