Yanhui Luo's research while affiliated with Capital Medical University and other places

Publications (9)

Article
Full-text available
Importance: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is considered the only effective treatment for chronic active Epstein-Barr virus infection (CAEBV). The clinical efficacy and safety of allo-HSCT with different conditioning regimens in children with CAEBV remain unclear. Objective: To evaluate the effectiveness and safet...
Article
Full-text available
Purpose Pediatric acute myeloid leukemia (AML) with KMT2A rearrangements has a very different prognosis. Poor outcomes cannot be avoided even after hematopoietic stem cell transplantation. In order to investigate the prognosis and efficacy, we conducted a retrospective analysis. Patients and methods We retrospectively analyzed a total of 32 childr...
Article
Full-text available
Objective To evaluate the clinical efficacy of haploidentical haematopoietic stem cell transplantation (haplo-HSCT) for the treatment of malignant infantile osteopetrosis (MIOP) and intermediate osteopetrosis. Methods Children with MIOP and IOP who underwent haplo-HSCT in Beijing Children’s Hospital, Capital Medical University, from January 2010 t...
Article
Full-text available
Importance Pediatric palliative care (PPC) is an interdisciplinary collaboration that focuses on the prevention and relief of patient suffering. PPC has emerged as a critical field of medical expertise and practice. However, no information is available regarding the progress of PPC in the Chinese mainland. Objective This study investigated the geo...
Preprint
Full-text available
Objective To evaluate the clinical efficacy of haploidentical hematopoietic stem cell transplantation (haplo-HSCT) for treatment of malignant infantile osteopetrosis (MIOP) and intermediate osteopetrosis.Methods Children with MIOP and IOP who underwent haplo-HSCT in Beijing Children’s Hospital, Capital Medical University, from January 2010 to May 2...
Article
Background Spiritual support should be offered to all patients and their families regardless of their affiliated status with an organized religion. Aim To understand nonreligious theistic parents’ spirituality and to explore how parents discuss death with their terminally ill children in mainland China. Design Qualitative study. Setting/particip...
Article
Full-text available
To investigate the cognitive and psychological outcomes of pediatric allogeneic HSCT survivors in China. A total of 135 3 to 18 years old children and adolescents who underwent allo-HSCT and survived at least 3 months post-HSCT were recruited and completed the assessments. Cognitive and psychological functions were assessed via age-appropriate stan...
Article
Full-text available
Background Long-term health-related quality of life (HRQoL) of pediatric patients after hematopoietic stem cell transplantation (HSCT) is increasingly studied worldwide. However, few studies have been performed in China, where no uniform scale is available; the PedsQL™ Cancer Module 3.0 Chinese Mandarin version has been used to evaluate HRQoL of pa...
Article
Objective To evaluate the quality of life (QOL) post hematopoietic stem cell transplantation (HSCT) for pediatric acute leukemia patients in mainland China. To analyze the influence factors of children’s QOL and compare the QOL between HSCT group and non-HSCT group. Methods Sixty 2-18 years old acute leukemia patients who received HSCT and got mor...

Citations

... Fully matched HSCT appeared to have a lower death rate, but the authors found no significant differences in the OS, EFS, or CIR rates between patient cohorts. The severity of aGVHD was higher in the group undergoing haplo-HSCT; however, only one haploidentical transplant patient died from aGVHD-related complications [91]. ...
... Although medical advances have significantly improved the survival rate of pediatric patients, each year, in mainland China, many children with life-limiting illnesses and their families continue to experience suffering and death without palliative care services [2]. In mainland China, most pediatric palliative care services are based in hospitals and large cities of the eastern provincial capital; moreover, most existing services mainly serve children with cancer [3][4][5]. ...
... pALG has been successfully used as first-line treatment in acquired severe aplastic anemia (20)(21)(22). It has also been employed for other hematological indications such as graft versus host disease prophylaxis (23). Meanwhile, pALG has been used in transplantation including hematopoietic stem cell transplantation (19,24,25) and kidney transplantation (26). ...
... In Mainland China, PPC has a shorter tradition. Chinese PPC has been slowly developed since 2010 [22], and so far, it is still in its early stage [23][24][25][26][27][28]. PPC there is almost exclusively implemented in hospital-based oncology wards [27]. ...
... [16][17][18][19] There are more worries regarding the side-effects of treatment, relapse, and even death among AYA patients than younger children. [20] In many children, the social development associated with the length of hospital stay, the length of isolation and absence of school. [21] A majority of HSCT survivors returned to school within 1-year post-HSCT. ...
... It is a well-established treatment for many acquired or congenital problems of the hematological system [1]. Despite being life-saving, the treatment is demanding and could have serious long-term side effects [2]. ...
... (3) Criterion-related validity: The Chinese version of the PedsQL 4.0, generic core scales (2-18 years old) was used as the calibration standard to test the calibration correlation validity. The higher the correlation coefficient (r value) between them, the better the correlation degree of the effective standard and the r value is between 0 and 1 (21). ...