Xiu-Hua Zhang's research works

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Schematic representation of Lignin@DEX/GLY, Lignin-loaded Dextran (DEX)/ Glycol (GLY) in the wound healing activity in before and after treatment

Structural characterisation of Lignin@DEX/GLY. The High resolution-scanning electron microscopy (HR-SEM) image showing the morphology of (A) DEX/GLY and b Lignin@DEX/GLY. Scale bar 20 µm

Mechanical properties of Lignin, DEX/GLY and Lignin@DEX/GLY. a Stress–strain curve of Lignin, DEX/GLY and Lignin@DEX/GLY. b Tensile strength of Lignin, DEX/GLY and Lignin@DEX/GLY. c Elongation curve of Lignin, DEX/GLY and Lignin@DEX/GLY. d Tensile modulus of Lignin, DEX/GLY and Lignin@DEX/GLY nanocomposite

Biodegradation and swelling ratio of Lignin, DEX/GLY and Lignin@DEX/GLY. a Biodegradation and b Swelling ratio of Lignin, DEX/GLY and Lignin@DEX/GLY nanocomposite using different days (1, 4, and 7)

Antibacterial and cell viability examination of control, DEX/GLY and Lignin@DEX/GLY. a Colony formation of S. aureus and E. coli. Scale bar 40 µm. b The corresponding Colony formation units. c Cell viability of control, DEX/GLY and Lignin@DEX/GLY. d The corresponding Cell viability plot. The experiments were repeated three times. Values are expressed as the mean ± SD. *p < 0.05, **p < 0.01. Scale bar 10 µm

Precise Engineering of Lignin Incorporated Dextran/Glycol Nanomaterials for Wound Dressings for the Care of Anorectal Surgery

January 2022

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8 Citations

Journal of Polymers and the Environment

Lignin-loaded nanoparticles are versatile nanomaterials that may be used in wound healing properties. The current study describes a wound dressing formulation focused on Lignin-loaded dextran/glycol (DEX/GLY) nanoparticles. The Lignin-loaded dextran/glycol membranes were fabricated using Lignin solutions inside the dextran/glycol medium. The influence of various experimental conditions on dextran/glycol nanoparticle formations were examined. The sizes of dextran/glycol and Lignin-loaded dextran/glycol nanoparticles were examined through the HR-SEM. Moreover, the efficacy antibacterial activity of dextran/glycol and Lignin-loaded dextran/glycol nanoparticles was evaluated against the microorganisms gram-positive and negative. Furthermore, we observed the in vivo wound healing of wounds in skin using a mice model over a 14 days period. In this difference to the wounds of untreated mouse, quick healing was observed in the Lignin-loaded dextran/glycol nanoparticles-treated wounds with fewer injury. These results specify that Lignin-loaded dextran/glycol nanoparticles-based dressing material could be a ground-breaking nanomaterial having wound repair and implantations potential required for wound injury in anorectal surgery model, which was proven using an animal model. Graphic Abstract

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... Lignin, which is an organic polymer compound, is known as an inexpensive waste produced via processing of by-products from paper, timber, and biomass industries and is equally prevalent in developing and developed countries [13,14]. Large amounts of lignin-based by-products, as solid powders/black liquids with high water content, are produced by paper and biomass industries following extraction of valuable fibers or pulp [15,16]. Lignin is a source of pollution that endangers human health and groundwater safety unless proper usage of lignin is developed [17]. ...
Reference:
Efficient Soil Stabilizers Against Wind Erosion Based on Lignin and Lignosulfonate Composites of Dubb Humic Acid as a Value-Added Material Extracted from a Natural Waste

Precise Engineering of Lignin Incorporated Dextran/Glycol Nanomaterials for Wound Dressings for the Care of Anorectal Surgery

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January 2022

Journal of Polymers and the Environment

Xiu-Hua Zhang's scientific contributions

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