X. Wu's research while affiliated with University of Texas MD Anderson Cancer Center and other places

... 8 All the adverse effects significantly affect life quality of AA patients. Most research shows that oxidative stress [9][10][11][12] and inflammation [13][14][15][16] are associated with the risks of various cancers. Marine algae have been found to be with various bioactive compounds, such as alginate oligosaccharide (AOS). ...

... All these findings highlight the importance of genetic variation in drug treatment. Nonetheless, similar studies on SCLC are rare (22,23). A few consistent associations have been reported for some individual susceptibility genes, but no general recommendations have been formulated to date (24)(25)(26). ...

... Single nucleotide polymorphisms (SNPs), the most common genetic variations in the human genome, occur once every 100-300 base pairs. Recently, an increasing number of studies have demonstrated that SNPs within miRNA-binding regions contribute to cancer risk and outcomes by altering miRNA-mRNA binding affinities and miRNA-targeted gene expression (9)(10)(11). ...

... The role of these variants in skin and lung cancers was investigated separately in previous GWA studies. [31][32][33][34] Other studies identified the association of rs401681variant with lung or skin cancers in other populations. 35,36 GGG haplotypic structure of rs4430796-rs11651052-rs11263763 ...

... Cholesta‐22, 24‐dien‐5‐ol, 4,4‐dimethyl was found to be useful in the treatment of antimicrobial anti‐inflammatory, anticancer, diuretic, antiarthritic, antiasthmatic diseases [15]. Campesterol have anticarcinogenic activity against prostate [16], lung [17] and breast [18, 19] cancers. Erucic acid commonly called as cis‐13‐docosenoic acid is a very‐longchain monounsaturated fatty acid was used as a raw material in the oleo chemical industry. ...

... CoP (Michaud et al., 1999;Zhou et al., 2014) CoR (Ahmad et al., 2012) CS (Braver et al., 1987) CC (Bruemmer et al., 1997;Hemelt et al., 2010;Jensen et al., 1986;Jiang et al., 2008;Radosavljevic et al., 2003;Villanueva et al., 2006;Wilkens et al., 1996) LtrEd (Bar-David et al., 2004) CoP (Ros et al., 2011;Zeegers et al., 2001;Zhou et al., 2012) SysR (Brinkman and Zeegers, 2008;Zeegers et al., 2004) Meta (Bai et al., 2014) NarR (Altieri et al., 2003;Lotan et al., 2013;Manz and Wentz, 2005) CC (Bianchi et al., 2000;Di Maso et al., 2016;Dunham et al., 1968;Geoffroy-Perez and Cordier, 2001;Slattery et al., 1988;Wang et al., 2013b;Wynder et al., 1963) (Brinkman and Zeegers, 2008;Hemelt et al., 2010;Jiang et al., 2008;Villanueva et al., 2006;Wilkens et al., 1996) Conflicting evidence (12:16) ...

... It has been reported to have an oncogenic effect in NSCLC; previous studies shown that miR-9 promotes proliferation, migration, and invasion ability by targeting tumor suppressor genes (9)(10)(11)(12). Meanwhile, a tumor-suppressive effect that could inhibit the malignant phenotype of NSCLC cell has also been reported (13)(14)(15). Besides, overexpression of miR-9 may enhance the radiosensitivity (14,16) and cisplatin sensitivity (17). However, previous studies on the effect of miR-9-5p in NSCLC patients were limited and lacking rigorous in vitro experimental verification. ...

... For genetic associations with tumor recurrence, studies mostly focused on NMIBC cases (except for few reports considering UBC group overall 49 or MIBC). 50, 71 The NMIBC recurrence was investigated as an overall outcome, 49,69,78,89,90,94,97,104,106 or in specific groups: patients younger than 64 years, 98 patients not treated with Bacillus Calmette-Guérin (BCG) therapy 40,43 ; BCG-treated patients 23,25,30,31,40,43,52,53,[79][80][81][82][83][85][86][87]93,95,96,99,100,102,103,107 ; patients treated only with transurethral urinary bladder tumor (TURBT) resection 88,101 ; patients who have received both TURBT and BCG treatments 91,92 ; patients having received treatments of TURBT and epirubicin 105 ; and recurrence only among low-risk NMIBC 14,84 (Supplementary Table 7). ...

... DNMT1 is commonly overexpressed in various cancers and is often linked to poor patient prognosis, as indicated by previous studies [59][60][61][62]. In our study, we have demonstrated a new discovery regarding DNMT1 expression, which progressively increased throughout epithelial multistage carcinogenesis. ...