Wen Jiang's research while affiliated with University of California, San Diego and other places

... With the changing epidemiological and clinical patterns of infectious diseases following the COVID-19 pandemic [27,28], it is becoming increasingly important to continue to monitor the burden of ENT infections in particular patient populations in order to provide actionable clinical data and to develop algorithms for appropriate management and followup, as is already available for other patient populations and other ENT involvements [29]. ...

... There is an extensive literature on adult thyroidectomy but relatively few reports on thyroidectomy in pediatric patients. There are known and important differences between these two populations, such as a higher incidence of postoperative complications in pediatric patients (1)(2)(3)(4). Hypocalcemia, the most frequent complication, is caused by the Abbreviations ASA, american society of anesthesiologists' physical status classification; Calcidiol, 25-hydroxyvitamin D; Calcitriol, 1,25-(OH)2-vitamin D; Cholecalciferol, vitamin D3; CT-Ca 2+ , corrected total serum calcium; MEN 2, multiple endocrine neoplasia type 2; iPTH, intact parathyroid hormone; PACU, post-anaesthesia care unit. removal of the parathyroid glands or a compromise to their vasculature (5,6). ...

... Furthermore, improvements in communication channels between hospitals and patients due to the pandemic may have encouraged more careful patient selection and screening of patients for surgeries, resulting in fewer cancellations. The same results were observed in a previous study [21]. ...

... A polysomnographic study (PSG) is the diagnostic technique of choice for quantifying sleep-disordered breathing and sleep architecture. PSG can be performed in children of all ages [29]. PSG is not only useful for diagnosis, but also allows the severity of the disease to be estimated, despite certain limitations: PSG is intrusive, cumbersome, and cost-prohibitive, and facilities that can provide PSG-based diagnostic services in children are not widely available. ...

... However, almost all ALK fusions share a breakpoint at exon 20, just upstream of the tyrosine kinase domain [10]. STRN::ALK gene fusions have been identified in a small percentage of thyroid, lung, renal, colorectal, prostate and breast cancers, as well as in mesotheliomas and pancreatic intraductal tubulopapillary neoplasms [11][12][13][14][15][16][17][18][19][20][21][22][23]. Two recent reports also show STRN::ALK fusion is a driver in some cases of salivary intraductal carcinoma; one arose within an intraparotid lymph node and the other was a frankly invasive carcinoma ex-intraductal carcinoma [24,25]. ...

... We want to stress the importance of the thorough diagnostic of patients with undefined autoinflammatory phenotype and if necessary, re-evaluate them with a time new information and updates are available. Such results potentially may improve treatment outcomes, as far most of defined SAIDs present favourable response to steroids, colchicine or IL1-blocking therapy [28][29][30]. Contrary to the favourable effect observed in PFAPA to tonsillectomy, or aberrant effect of steroids, patients with undefined SAIDs rarely will perform the same response. But uSAID/SURF patients perform a favourable response to colchicine therapy, where in severe cases IL-1 therapy may dramatically resolve clinical presentation [31]. ...

... In 2019, Cherella et al. reported malignancy rates of 44% and 71% for AUS and SFN nodules, respectively (4). Published pediatric studies show that the malignancy rates for Bethesda 3 nodules range from 8.3% to 44% (4,21-23) and for Bethesda 4 nodules range from 35% to 100% (23)(24)(25). These studies suggest that the rates of malignancy both groups have been different rates but the risk of malignancy in pediatric patients with Bethesda 4 nodules is relatively high compared to Bethesda 3. Multiple ultrasound scoring systems are available to categorize nodules for fine-needle biopsy (FNB) indications, including fine-needle cytology (10,26). ...

... 3 In general, one of the goals of telemedicine is to expand healthcare access by providing remote monitoring and consultation to patients. 4,5 Therefore, the adoption of telemedicine increased in different countries during the COVID-19 pandemic due to a context of reduced personal contacts. [6][7][8] According to the 2020 report by the Portuguese Directorate General of Health (DGS), there was a significant increase in telemedicine consultations during the initial months of the COVID-19 pandemic compared to the corresponding period of the previous year. ...

... In short, all the authors report that it is a simple procedure, with a positive outcome for the symptoms presented and reinforce the importance of a complete, careful and multidisciplinary assessment with a view to correcting posture, latch and any other factor that may influence breastfeeding, before indicating the intervention. The authors found a positive outcome mainly for babies with severe ankyloglossia (classes III and IV of the Kotlow classification) ( Barberá-Pérez et al., 2021;Bundogji et al., 2020;Dollberg et al., 2006;Donati-Bourne et al., 2015;Ferrés-Amat et al., 2016;Jamani et al., 2020;Lam et al., 2020;Martinelli et al., 2015;Nogueira et al., 2021). ...

... Conversely, these conditions can also result in a significant decrease in levels of albumin and lymphocytes. [7][8][9][10][11][12] Positive acute phase reactants, such as c-reactive protein (CRP), have intricate pathophysiological processes that result in stress-induced leukocytosis, with or without clinically significant hypoalbuminemia. Measuring neutrophil levels in a sequential manner, particularly after the onset of stress-related illness, is a useful independent risk factor for evaluating the mechanism of acute infections. ...