Timea Dako's research while affiliated with University of Medicine and Pharmacy of Târgu Mures and other places

Introduction: One of the main elements of facial esthetics is represented by the smile. A harmonious proportion between the elements of facial esthetics is an important subject of interest in dentistry. Aim of the study: This research aims to evaluate the impact of the gummy smile on future dental practitioners. Materials and Methods: A survey containing 16 questions was designed to find out the students’ perceptions about the ideal smile and if the gingival smile is considered youthful or unpleasing. The impact on their self-esteem, their willingness to change the gummy smile or not, the nonsurgical and surgical methods of treatment were also evaluated. Results: 212 answers were recorded and analyzed. Nearly three quarters (70.3%) of the respondents believe that having a gummy smile is unesthetic, while only 29.3% considered it to be a sign of youth. Self-esteem can be affected by having a gingival smile, but, according to the results, most of the students (45.8%) said that their daily lives have not been affected by it, 40.6% said that in a small amount, 10.4% said that their self-assurance has been very affected and only 3.3% admitted that the gummy smile distressed their confidence. When asked if they were willing to correct their gingival smile, 51.4% were open to improving it while 48.6% would not change it. Conclusions: Among dentistry students, excessive showing of the gums is believed to be unesthetic rather than a sign of youthfulness. The respondents are generally not affected in their daily life by having a gummy smile. Education regarding the methods of correcting it still needs to be addressed amongst future dental practitioners.

White spot lesions, pathologically characterized by enamel demineralization, present a significant challenge in dentistry. Notably, intervention at the white spot stage is crucial to impede further lesion progression. Recent advances studies have demonstrated the effectiveness of flowable resin infiltration as a minimally invasive alternative to traditional treatment modalities. This technique allows for the concurrent treatment of multiple lesions in a single appointment, circumventing the necessity for local anesthesia or extensive cavity preparation. Clinically, this method has shown consistent stability, evidenced by maintained enamel integrity, enhanced rigidity, and preservation of adjacent healthy dental tissues. Additionally, the aesthetic outcomes of this approach are noteworthy, with a gradual diminution of lesion visibility over time. The present case report elucidates the long-term clinical outcomes and the efficaciousness of the Icon kit in the targeted management of specific white spot lesion pathologies.

(1) Background: Early diagnosis and treatment of peri-implant mucositis may reduce inflammatory markers and halt the progression of the condition to peri-implantitis. Adjunctive laser treatment may have therapeutic benefits that are not yet well known. The aim of this study was to determine the advantages and limitations of laser therapy as an adjuvant in the treatment of peri-implant mucositis. (2) Methods: A total of 42 patients with at least 2 implants situated in different hemiarches were included in this study and divided into two groups: G1 (received laser therapy) and G2 (no laser therapy). Periodontal health status indices were recorded at the initial moment (T0), and all patients underwent non-surgical debridement therapy accompanied by oral hygiene training. In patients from group G1, one implant site received adjuvant laser therapy (subgroup IL), and the other one did not receive active laser light (IC). The plaque index (PI), probing pocket depth (PPD), and bleeding on probing (BOP) values recorded after 3 months (T1) and 6 months (T2) were analyzed and compared with those at T0. (3) Results: PI values considerably reduced at moment T1 and T2 for both G1 and G2 (p = 0.0031). PPD was also reduced, but the difference between the groups and the three recording moments was not statistically significant. Statistically significant differences were found when comparing the BOP values between G1 IL and G1 IC for T0/T1 (p = 0.0182) and T1/T2 (p < 0.0001), but there was no significant difference between G2 and G1 IL or G1 IC. (4) Conclusions: Laser therapy as an adjunct to conventional treatment of peri-implant mucositis leads to a statistically significant reduction in bleeding on probing at 3-month and 6-month re-evaluations. Moreover, it leads to an evident reduction in probing depth but with no statistical significance. These results should be interpreted with caution, and more in-depth research should be performed to create a complete laser therapy protocol for peri-implant mucositis.

Noncarious cervical lesions (NCCL) have a multifactorial etiology. The terms abfraction, abrasion, and erosion are also used to describe the same lesion. NCCLs can lead to gum recession which is one of the most frequent gingival defects. NCCLs generally also involve loss of tooth structure. Therefore, treatments should be planned and performed in an interdisciplinary manner. When NCCL is minimal, the choise to use simple direct restorations is the main therapeutic option. If it is serious, microsurgical treatment or, more precisely, interdisciplinary treatment might be necessary. Root coverage by microsurgical methods is the most challenging esthetic procedure. There are many techniques available of which we must always choose the method that can ensure and control root coverage in the long term.

Acute lymphoblastic leukemia (ALL) is a malignant condition defined by the proliferation of immature hematopoietic bone marrow cells, which replace the normal bone marrow elements. Furthermore, immature cells will accumulate in various areas of the body. Chemotherapeutic drugs are cytotoxic and have unwanted effects on normal cells. This toxicity is acute, or it may be chronic. Approximately 60% of survivors of ALL will suffer from one or more health problems or adverse side effects of this treatment. Oral complications are a frequent consequence of oncology therapy in pediatric patients. Xerostomia, carious lesions, gingivitis, tumors of the oral cavity, bone deformities of the jaw, temporomandibular joint disorders, trismus, and infections due to abundant microbial flora are common in these children. The risk of dental anomalies (dental or root agenesis, root malformations, enamel defects, dental hypoplasia) is higher in those who started treatment before permanent teeth erupt. All children are at risk of developing oral lesions due to poor hygiene, but children who have survived cancer are at even higher risk. The survival rate of children diagnosed with ALL has significantly increased thanks to remarkable advances in chemotherapy. Therefore, it is important that these patients are constantly monitored by the dentist to treat complications arising from the treatments in a timely manner. In children diagnosed with ALL, oral health is of great importance as the oral environment changes as a side effect of hematological disorders and their treatments. Treatment of carious lesions, periodontal problems and lesions of the oral mucosa must be done before starting chemotherapy by cleaning the oral cavity to eliminate any possible risk of infection. The participation of the dentist is important in improving the preventive protocols and oral examination of the pathological processes that occur in children with ALL. Interdisciplinary collaboration between physicians is essential during the treatment of pediatric cancer patients.

Background: In the last decades, adult patients require orthodontic treatment as a therapeutic method in an increasing percentage. This treatment has a lot of benefits, but unfortunately it also presents a number of complications and risks, among which favoring the accumulation of bacterial plaque is the most concerning. Aim of the study: In this study we aimed to evaluate the effectiveness of using the dark-field microscope as a method of motivating adult patients with orthodontic treatment in maintaining a proper oral hygiene. Material and methods: Thirty-six patients were selected based on the inclusion and exclusion criteria. At time T0, patients were divided into two groups: Group 1–microscope and Group 2 – control, in such a way that the groups were as homogeneous as possible. Dental plaque samples were collected and analyzed under a dark field microscope in the presence of the patient for subjects from Group 1 but not Group 2. All patients were then instructed on oral hygiene techniques. The following periodontal indices were recorded of each patient: plaque index (PI), index of bleeding on probing (BOP), probing depth (PD) – at T0 and T1 (after one month). Results: Comparing the PI and BOP values before (T0) and after treatment (T1), statistically significant results were detected (PI: p = 0.0020, BOP: p = 0.0297), which denotes that patients who observed the bacterial load of their dental plaque in real time using the dark-field microscope had a better oral hygiene and lower values of periodontal health indices. Regarding the PD index, the difference between time T0 and T1 was not statistically significant (p = 1.4762). Conclusions: During the orthodontic treatment, adult patients often present gingival inflammation caused by improper hygiene. The use of the dark-field microscope is effective in motivating patients regarding the rules of maintenance of a proper oral hygiene.

Orthodontic treatment with fixed devices should only be indicated in case of a stable, non-active periodontal disease status. Throughout orthodontic treatment, a careful assessment of the periodontal status is advised. Due to its anti-inflammatory and antimicrobial effects, laser therapy is frequently used as an adjunct to classic periodontal therapy. The aim of this study was to evaluate the advantages and limitations of the use of laser therapy on periodontal status during orthodontic treatment. Throughout the 9 months during which this placebo-controlled, single-blind clinical trial was conducted, 32 patients were included in the study, divided into two groups: microscope “+” (patients who observed the bacteria within the dental plaque-sample examination on the screen of a dark-field microscope in real time) and microscope “−” (patients who did not see the oral pathogens using a dark-field microscope). For all patients, using the split-mouth study design, laser therapy was applied to one hemiarch (HL), whereas the other hemiarch received treatment without active light (HC). After one month, by analyzing the main indicators of periodontal health status, we found that the plaque index (PI) and bleeding on probing (BOP) values were significantly decreased after receiving treatment (for PI: HL-p = 0.0005, HC-p = 0.0297; for BOP: HL-p = 0.0121, HC-p = 0.0236), whereas the probing-depth (PD) values remained almost the same as before treatment (HL-p = 1.5143; HC-p = 1.4762). Conclusions: The use of the dark-field microscope proved to be beneficial in sensitizing patients to the presence of bacteria in the oral cavity and motivated them to strictly follow the rules of oral hygiene. Laser treatment can be a valuable aid in periodontal therapy, but only in adjunction with mechanical therapy.

Dental sealants are excellent means to prevent pits and fissure caries. Nowadays, the application of sealants is extended to therapeutic use in arresting non-cavitated carious lesions. This relatively new concept still lacks evidence to support its routine use. The aim of this study was to evaluate the effectiveness of a resin-based sealant applied on first permanent molars with carious lesions (ICDAS 1–3), in comparison with its effectiveness when applied on sound surfaces (ICDAS 0). Included in the study were 114 children aged between six and eight years old, with a high caries risk (according to the CAMBRA system), with all four permanent molars erupted and with deep pits and fissures. A total number of 407 molars were sealed and assessed. A total of 49 were excluded (they had caries, which according to the ICDAS II classification were classified with code 4–6 or had older sealants or fillings). Out of these 407 molars, 213 were sound (code 0) and 194 had caries lesions as follows: 56 teeth classified as code 1, 79 teeth classified as code 2, and 59 teeth classified as code 3 according to the ICDAS II classification. The retention of the sealant and carious lesions were assessed clinically at 6, 12, 18, and 24 months. Regarding sealant retention, a statistically significant difference (p < 0.05) among the two types of sealed teeth, sound (ICDAS 0) and decayed (ICDAS 3), showed at 18- and 24-month follow-up intervals. Regarding caries lesions, a statistically significant difference (p < 0.05) showed between sound (ICDAS 0) and decayed (ICDAS 3) molars at 24-month follow-up. Our study results supported the resin-based sealant effectiveness in arresting incipient carious lesions, which according to the ICDAS II classification have received codes 1 and 2 but did not support sealant effectiveness in arresting caries lesions classified according to the same classification with code 3.

Dental ankylosis is a serious condition defined as the process that causes the fusion between the dentin or the cementum of the root and the alveolar bone, with the obliteration of the periodontal ligament becoming progressively replaced by bone tissue. The aim of the study was to determine the prevalence, location, severity, and association of dental ankylosis in primary molars with other dental anomalies such as the agenesis of permanent buds. For this study 150 panoramic x-rays were selected from patients with temporary or mixed dentition, aged six to twelve years old, from a private dentistry office and from the Pediatric Dentistry Department of UMFST in Targu-Mures, Romania. In order to identify the cases with dental ankylosis, the presence and severity of the infraocclusion, displacements of the neighboring teeth, the appearance of the root area, and the relationship with the bone tissue were examined. For evaluation of the categorical data we used Fischer’s exact test and the Chi-squared test and the chosen significance level was set at 0.05. The results showed that the highest percentage of cases with ankylosis was found in the first group (six to nine years old), respectively, with 72% of cases compared with the second group (ten to twelve years old) with 28% of cases. Findings showed that there was no positive association between dental ankylosis and gender, but a strong correlation was found regarding the location on the dental arches. Most cases were identified on the lower arch with a higher percentage in quadrant three. Of the two primary molars, the most affected by ankylosis was the first molar in quadrant three, followed by the second molar, and finally the first molar in quadrant four. Most cases diagnosed with ankylosis had a mild to moderate degree of infraocclusion; therefore, changes in the functional balance of the dental arch and on neighboring teeth were insignificant. There were some differences obtained between our results and studies from the literature, especially regarding the localization in the lower left dental arch, but these differences can be attributed to the number of the subjects selected and from the methodology of dental ankylosis diagnosis. Based on the data obtained, it was concluded that ankylosis is a dental condition which occurs in children in early mixed dentition, especially in the lower arch, with the first primary molar being the most affected tooth. The presence of infraocclusion and the absence of dental mobility, especially during the stage of primary molars’ root resorption, are the main signs which must be followed to make an early diagnosis and prevent further complications.

Periodontal disease is believed to be an opportunistic infection due to the interaction of bacterial plaque and the patient’s response that may be influenced by environmental, genetic, and other risk factors. In addition to the fact that smoking is considered a risk factor in many systemic diseases, it has also been associated with the initiation of periodontal disease. Smoking is one of the modifiable risk factors and has a significant influence on the development, progress, and results of the treatment of periodontal disease. The current state in the field of study suggests that smoking aids the colonization of periodontal microorganisms, accelerating the onset of periodontal disease. Biological modifications in pathogens, such as Porphyromonas gingivalis, along with poor immune response, influence the variations of subgingival flora in smoking patients. Only with an individual approach can the risk factors of each patient be identified and satisfactory results obtained. The aim of this paper is to present a comprehensive review of the influence of smoking on periodontal microbiome and the importance of adopting the appropriate treatment method according to the influence of this risk factor on healing.