Tiffany Grunwald's research while affiliated with Saint John's Health Center and other places

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Publications (1)


Fig. 1 A preoperative image of the congenital DST in the posterior cervical region at the C2-C3 level. The DST presented as hypopigmented, no signs of infection, and contracted external sphincter-like outer boundary with hypotrichosis.
Fig. 2 Preoperative cervical MRI indicated a tract from the epidermis at the C2 level, coursing rostrally and communicating with the dura at C1. The C1 bifid arch is traversed by the congenital dermal sinus tract.
Fig. 3 Intraoperative image of the DST communicating with the dura. Under high microscopic magnification the DST is visualized along its tract all the way to the epidural space and at the very center the C1 lamina is reached and the area of decompression is visualized.
Fig. 4 Intraoperative image of the sinus tract. Sinus tract length is measured to be 7.5 cm, including the redundant epidermis: the abnormality was submitted for pathological examination upon excision and this was a result of the gross total resection.
Fig. 5 Closure of the congenital DST at the 3 months postoperative mark. Results demonstrated achieved by z-flap plastic surgical closure attained effective cosmesis.

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Posterior cervical congenital dermal sinus tract: case report and review of literature
  • Literature Review
  • Full-text available

August 2023

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67 Reads

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1 Citation

Spinal Cord Series and Cases

Amir Vokshoor

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Harseerat Jajj

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Tiffany Grunwald

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[...]

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Jack Petros

Background and importance Congenital dermal sinus tract (DST) is a rare spinal dysraphism characterized by a persistent tract lined by epithelial cells, beginning at the epidermis and terminating in deeper tissue layers. With 1% of all congenital DST cases found in the cervical region, only 4% of all cases are diagnosed after the age of 20. Clinical presentation In this case, a 65-year-old woman with a congenital DST at the cervical level presented with symptoms of neck and some arm pain, suboccipital headaches, and unique external characteristics. Neck Disability Index and visual analog scale were used to assess the patient’s preoperative and postoperative pain, and quality of life. Patient underwent an operative intervention, where the DST was surgically removed followed by interlaminar decompression at C1–C2, excision of the epidural component, and biopsy followed by plastic surgical repair. Pathology analysis indicated a squamous epithelial-lined sinus tract interacting with the dura. Most notably, a meningothelial proliferation with associated psammomatous calcifications was identified, similar to a meningioma. Conclusion A review of literature was conducted to further discuss clinical and radiological presentation as well as to document the novel appearance of this congenital DST. As one of the oldest cases of DST, it demonstrated unusual pathological characteristics with a meningothelial proliferation, compatible with meningioma, reported at the epidural level.

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Citations (1)


... Patients often present with gradual and insidious neurological deficits. These deficits manifest as motor weakness, where patients experience a gradual decline in muscle strength, leading to difficulties in movement and coordination [5,6,8,[20][21][22]. In contrast, sensory alterations involve disruptions in normal sensory perception, such as numbness, tingling sensations, or even loss of sensation in certain body areas. ...

Reference:

Intradural intramedullary epidermoid cyst in a 17-year-old male: An exceptionally rare case report and review of the literature
Posterior cervical congenital dermal sinus tract: case report and review of literature

Spinal Cord Series and Cases