Shuli Zhi's research while affiliated with Huazhong Agricultural University and other places
What is this page?
This page lists the scientific contributions of an author, who either does not have a ResearchGate profile, or has not yet added these contributions to their profile.
It was automatically created by ResearchGate to create a record of this author's body of work. We create such pages to advance our goal of creating and maintaining the most comprehensive scientific repository possible. In doing so, we process publicly available (personal) data relating to the author as a member of the scientific community.
If you're a ResearchGate member, you can follow this page to keep up with this author's work.
If you are this author, and you don't want us to display this page anymore, please let us know.
It was automatically created by ResearchGate to create a record of this author's body of work. We create such pages to advance our goal of creating and maintaining the most comprehensive scientific repository possible. In doing so, we process publicly available (personal) data relating to the author as a member of the scientific community.
If you're a ResearchGate member, you can follow this page to keep up with this author's work.
If you are this author, and you don't want us to display this page anymore, please let us know.
Publications (4)
Numerous studies have shown that exosomes play a regulatory role in a variety of biological processes as well as in disease development and progression. However, exosome-mediated intercellular communication between brain microvascular endothelial cells (BMECs) and astrocytes during meningitic Escherichia coli (E. coli)–induced neuroinflammation rem...
The blood–brain barrier is a specialized structure in mammals, separating the brain from the bloodstream and maintaining the homeostasis of the central nervous system. The barrier is composed of various types of cells, and the communication between these cells is critical to blood–brain barrier (BBB) function. Here, we demonstrate the astrocyte-der...
Aim: To investigate the mRNAs and noncoding RNAs (ncRNAs) expression in astrocytes upon meningitic-Escherichia coli infection. Materials & methods: The transcription of mRNAs and ncRNAs were fully investigated and profiled by whole transcriptome sequencing and bioinformatic approaches. Whole transcriptome differences between the infected astrocytes...
Citations
... Astrocytes and BMECs play crucial roles as gatekeepers, with their communication being essential in limiting the entry of leukocytes into the brain parenchyma. For instance, in the context of neuroinflammation, the interaction between astrocytes and endothelial cells can stimulate an increase in BBB permeability, resulting in peripheral immune cell infiltration [14,16]. Astrocyte-secreted VEGF-A can induce downregulation of endothelial nitric Xinyi Qu and Ruicheng Yang contributed equally to this work. ...
... Conversely, astrocytes can also produce substances that enhance BBB integrity. For example, under inflammatory conditions, astrocytes contribute to BBB stability through the production of TGFβ1 or sonic hedgehog (Shh) [20,21]. Overall, these findings underscore the significance of astrocyte-endothelial cell communication in regulating BBB function during CNS inflammation. ...
... In extraintestinal infections, such as those affecting the brain, significant alterations in lncRNA expression patterns have been observed. Astrocytes and human brain microvascular endothelial cells show differential transcription of 74 and 289 lncRNAs, respectively, during E. coli infections [50,51]. Among these, lncRSPH9-4 functions as a regulatory sponge, maintaining blood-brain barrier integrity by competitively interacting with miR-17-5p and matrix metallopeptidase 3 (MMP3) [52]; while lncC11orf54-1 and DDIT-AS1 mediate central nervous system inflammatory responses by interacting with interleukin 1 receptor associated kinase 1 (IRAK1) and DNA damage inducible transcript 4 (DDIT4) mRNA, respectively [51,53]. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/11431281108201625-1671417400359_Q64/Bo-Yang-26.jpg)
![[object Object]](https://i1.rgstatic.net/ii/profile.image/11431281108196123-1671382640319_Q64/Bojie-Xu.jpg)
... 5,6 Thus, in recent decades, L. monocytogenes has become a major concern in the food industry and public health, and the identification of L. monocytogenes species for food safety, epidemiological studies, and clinical diagnosis became very critical. 7 There are several methods for the classification of bacterial isolates, such as Multilocus Sequence Typing (MLST), Pulsed-Field Gel Electrophoresis (PFGE), and restriction enzyme analysis. 8,9 Although each of these methods has its advantage in isolating different bacterial species, the typing technique should be simple and easy. ...
