Seong-Jang Kim's research while affiliated with Pusan National University Yangsan Hospital and other places

... Positron Emission Tomography (PET) is a molecular imaging technique that enhances diagnostic performance (2), therapeutic response monitoring (3), prognosis evaluation (4,5) and modifies the management of patients with hematological (6) or solid malignancy (7). However, it is sensitive to attenuation. ...

... Positron emission tomography (PET) imaging using 2-deoxy-2-[ 18 F] fluoro-d-glucose ([ 18 F] FDG) as an imaging agent plays a pivotal role in oncology, e.g., cancer diagnosis and staging. [ 18 F] FDG is a marker of energy metabolism and cell proliferation, and it is routinely used in the clinic to evaluate patient responses to chemotherapy [3][4][5][6], and it can be used to monitor tumor growth. Treatment with some tyrosine kinase inhibitors (TKIs) may cause changes in blood glucose levels [2,7,8]. ...

... Rapid molecular diagnostic tests (RMDTs), which can be conducted at the laboratory or at the point of care (PoC), are a type of molecular assay that can yield results in as fast as 15-30 minutes [21]. Over the past two decades, numerous systematic literature reviews (SLRs) and meta-analyses (MAs) have sought to identify and describe evidence on the diagnostic performance of RMDTs for respiratory infections in terms of sensitivity, specificity, and positive and negative predictive values [22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41]. However, fewer SLRs/MAs have summarized and synthesized evidence on the impact of these tests in terms of therapeutic decisions and patient outcomes. ...

... CMR has higher sensitivity compared with FDG-PET-CT in distinguishing benign from malignant cardiac tumors, while FDG-PET-CT has higher specificity. The combination of these modalities increases the diagnostic yield for malignant tumors [18]. In patients with hybrid magnetic resonance/PET scanning, when it is desired to differentiate between benign and malignant cardiac masses, 18F-FDG-PET scanning has a sensitivity of 100% and a specificity of 92% [4]. ...

... A meta-analysis of using delayed [ 18 F]FDG PET for differentiating benign and malignant pulmonary nodules failed to demonstrate a bene t for delayed imaging [13]. Conversely, a meta-analysis of 758 patients concluded that the diagnostic accuracy of [ 18 F]FDG PET for mediastinal lymph node metastases was improved by using the retention index of [ 18 F]FDG calculated from dual time point imaging [12]. ...

... The accuracy of [ 18 F]FDG PET/CT in detecting nodal disease in penile cancer is variable and mainly associated to the clinical stage of lymph nodes (Figure 6). A recent meta-analysis of 12 studies [143] reported a good diagnostic performances for detection of metastatic lymph nodes with a pooled sensitivity of 87% and a pooled specificity of 88%, without discriminating between non-palpable and palpable nodes. In case of nonpalpable lymph nodes (cN0), PET/CT detection rate is suboptimal. ...

... Subcutaneous Adipose Tissue (SAT), although it is the most abundant depot in the body, has a lower association with obesity-related complications, whereas Visceral Adipose Tissue (VAT), which surrounds internal organs, is metabolically more active and releases a higher amount of pro-inflammatory adipokines compared to SAT. VAT is strongly associated with metabolic syndrome, insulin resistance, and an increased risk of cardiovascular diseases [23,24]. Adipose tissue produces and releases various signaling molecules, collectively known as adipokines, such as adiponectin, leptin, and resistin [25][26][27][28]. ...