SamarG Soliman's scientific contributions

... Dutta et al. (25) reported that percutaneous radio-frequency ablation is more effective than intraarticular methylprednisolone injection for SIJ Pain in selected patients with similar demographics. Soliman et al. (26) compared the effect of steroid and platelet rich plasma (PRP) and found that both were effective in relieving pain and improving function and disability in treatment of sacroiliitis by ultrasound guided injection, but PRP was more efficacious than the steroid with longer lasting effect. On the other hand, Kim et al. (27) compared intra-articular concentrated dextrose prolotherapy to intra-articular corticosteroid for sacroiliac joint dysfunction and found that dextrose injections led to prominent analgesic effect compared to corticosteroid. ...

... 43 Similarly, Soliman S et al., concluded that TNF-α levels in children with spastic CP are positively correlated with disease severity, showing a significant difference between pretreatment levels of TNF-α, which improved after rehabilitation and correlated with improvement in all outcome measures. 44 Conclusions BDNF has been shown to have a significant relationship with brain development early in life. However, further studies are needed to assess its value as a biomarker and/or as a treatment to enhance or avoid further complications of CP as still there is insufficient progress in prediction, early diagnosis, treatment, and prevention. ...

... Six randomized controlled trials met inclusion criteria and were included in this meta-analysis. 11,13,27,33,36,38 Altogether these studies included 214 subjects in the PRP group and 218 subjects in the ESWT group. The characteristics of the included studies are summarized in Table 1. ...

... These elevated sTREM-1 levels were shown to have a substantial correlation with a variety of clinical and laboratory markers of disease activity. However, the relationship between sTREM-1 and radiological damage or functional capacity has not been specifically addressed or examined in these research (29). sTREM-1 in RA patients there was significant correlated with WBC (Table 7 and Figure 9) Since there were connections between the levels of sTREM-1 and WBC in the present study, plasmasTREM-1 may be secreted by macrophages, monocytes, or neutrophils in patients with RA. ...

... Various forms of Ns are also encountered in RA as a result of PNS damage. In the study by El-Hewala et al. 42 , a group of 50 patients with RA was studied. Regardless of the DA, EP findings demonstrated N in 78% of patients, out of which 48% had compressive (entrapment) Ns, while the remaining 30% had symmetrical PoN with axonal degeneration. ...

... 4 It has been previously hypothesized that H. pylori can induce such immune host response through many mechanisms as the molecular mimicry and antigenic similarity, disruption of the tolerogenic immune response, and activation of the polyclonal lymphocytes leading ultimately to the imbalance between T regulatory/Th17 cells in addition to the induction of autoantibody production. 5,6,7 The association between H. Pylori and autoimmune diseases has been reported in idiopathic thrombocytopenic purpura, 8 chronic idiopathic urticaria 9 , auto-immune thyroiditis 10 , autoimmune atrophic gastritis, 11 and some other rheumatic autoimmune disorders as rheumatoid arthritis (RA), 12,13,14 systemic lupus erythematosus (SLE), 15 Sjogren syndrome, 16 and ankylosing spondylitis (AS). 17 On the other hand, a protective role of H. Pylori in some inflammatory conditions as multiple sclerosis, 18 inflammatory bowel disease 19 and allergic conditions as pediatric asthma 20 has been reported. ...

... 32 Furthermore, the same observation was reported by many studies from different populations. 40,41,42,43 In this study there was a significant positive relation between IL-17 serum level and DAS28 (r = 0.42, p<0.0001), the higher serum IL-17 level coincided with higher disease activity in RA, which reflected its contribution in inflammatory process, responsible for RA. This result agreed with several studies that detected a significant correlation between serum levels of IL-17 with disease activity DAS28. ...