Sachio Totokawa's research while affiliated with Kyushu University and other places

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Publications (1)

Evaluation of Treponema Pallidum Hemagglutination Test (TPHA Test), New Method Originated in Japan
  • Article

February 1969

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1 Read

Nishi Nihon Hifuka

Sachio Totokawa

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Takehide Kikuchi

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Kousaku Morita

215 nonsyphilitic sera and 105 syphilitic sera were examined by TPHA test (to use as antigen formalin treated tanned sheep red blood cells sensitized by T. P. Nichols strain and testing sera absorbed with T. P. Reiter strain and etc.,). Results: 1) On the nonsyphilitic sera 195 gave negative results to both of STS and TPHA, 6 gave positive results to TPHA and negative to STS, 14 gave negative results to TPHA and positive to STS. Then these were regarded as BFP, coinciding with results to FTA-200. 2) On the syphilitic sera 101 gave positive results to both of STS and TPHA. The reactivity to TPHA has been persistent after the antiluetic treatment. The sensitivity and spicificity of TPHA on syphilis might be satisfactory as that of FTA. Then the advantage of TPHA might be the stable graded agglutination figure on the hollow plastic plate for the test. © 1969, Western Division of Japanese Dermatological Association. All rights reserved.

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