Ruilian Jia's research while affiliated with South China Agricultural University and other places
What is this page?
This page lists the scientific contributions of an author, who either does not have a ResearchGate profile, or has not yet added these contributions to their profile.
It was automatically created by ResearchGate to create a record of this author's body of work. We create such pages to advance our goal of creating and maintaining the most comprehensive scientific repository possible. In doing so, we process publicly available (personal) data relating to the author as a member of the scientific community.
If you're a ResearchGate member, you can follow this page to keep up with this author's work.
If you are this author, and you don't want us to display this page anymore, please let us know.
It was automatically created by ResearchGate to create a record of this author's body of work. We create such pages to advance our goal of creating and maintaining the most comprehensive scientific repository possible. In doing so, we process publicly available (personal) data relating to the author as a member of the scientific community.
If you're a ResearchGate member, you can follow this page to keep up with this author's work.
If you are this author, and you don't want us to display this page anymore, please let us know.
Publications (5)
To grow and survive within host cells, Toxoplasma must scavenge necessary nutrients from hosts to support its parasitism. Transporters located in the plasma membrane of the parasites play critical roles in nutrient acquisition. Toxoplasma encodes a large number of transporters, but so far, only a few have been characterized.
Zoonotic Cryptosporidium parvum infections are mainly caused by IIa and IId subtypes. As most biological characterizations have been performed on IIa subtypes, the biological and genetic characteristics of IId subtypes in China are not clear. We evaluated the infection and genetic characteristics of IId isolates in interferon-γ-knockout mice using...
Nonhuman primates (NHPs) are considered an important source of parasitic zoonoses. A study in 2010 revealed high prevalence of Cryptosporidium spp. in free-ranging rhesus monkeys (Macaca mulatta) in a public park in Guiyang, southwestern China, which called for the control of disease in animals and long-term epidemiological tracking of Cryptosporid...
The small Cryptosporidium genome (∼9 Mb) has over 20 copies of genes encoding insulinase-like proteases (INS), suggesting that these enzymes may have important biological functions in the pathogen and could be developmentally regulated. In this study, INS-5, a unique member of the INS family in Cryptosporidium parvum, was cloned and expressed in Es...
Cryptosporidium spp. are important causes of diarrhea in humans, ruminants, and other mammals. Comparative genomic analysis indicated that genetically related and host-adapted Cryptosporidium species have different numbers of subtelomeric genes encoding the Cryptosporidium-specific MEDLE family of secreted proteins, which could contribute to differ...
Citations
... Major research on immune system invasion by a parasite helps in understanding and improving immunity boosters and drug development. Research and development are constantly going on, funded by several pharmaceutical companies and the government (Cui et al. 2022). Current research is focused on the development of new treatments and vaccines to overcome the risk of parasitic infection (Brake et al. 2022). ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/790291070062592-1565431482175_Q64/Bang-Shen-2.jpg)
... In recent years, this strain has undergone significant changes in subtype identity, resulting in reduced virulence in mice. In contrast, several IId subtypes from China induce more intensive infection in mice and are more virulent than the IOWA strain [14]. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/279653785849856-1443686066207_Q64/Yaqiong-Guo-3.jpg)
... Nucleotide sequences of the actin and 70 kDa heat shock protein (hsp70) genes were obtained from the whole genome sequence (WGS) data of C. equi (see section 2.5). Phylogenetic relationship among common Cryptosporidium species and genotypes was determined by the maximum likelihood analysis of sequences of the SSU rRNA, actin, hsp70, and gp60 genes, based on substitution rates calculated with the GTR + G + I model and bootstrapping with 1,000 replicates (Jia et al., 2022). Pairwise distances were calculated with p-distance model (Ježková et al., 2021). ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/11431281189923106-1695203007873_Q64/Yaqiong-Guo-8.jpg)
![[object Object]](https://i1.rgstatic.net/ii/profile.image/1125741056000001-1645408991997_Q64/Lihua-Xiao-2.jpg)
![[object Object]](https://i1.rgstatic.net/ii/profile.image/283894353022989-1444697098883_Q64/Na-Li-94.jpg)
... An increase in INS-5 mRNA expression of C. parvum-infected cells was reported after 12 h of contact, while peak expression was observed between 36 to 48 h, suggesting participation in the growth process. Moreover, the polyclonal antisera reduced the invasion in the target cells, also demonstrating participation in this process [72]. Recently, INS1 was identified as belonging to M16A, with a signal peptide and one active domain in the HLIEH motif, encoded by the cgd1_1680 gene. ...
... Serine protease Excystation [115] Arginine aminopeptidase Excystation [116] CSL Attachment, invasion [117] gp900 Invasion [118,119] gp40/15 Invasion, motility [21,120,121] TRAP-C1 Invasion, motility [122] CP47 Attachment [123] CpMIC1 Attachment, invasion, motility [124] P23 Attachment, motility [125,126] P30 Attachment, invasion [127] CPS-500 Attachment, motility [128] CpClec Attachment, infection [129] INS-15 Invasion [130] Cp2 Attachment, motility [131] Cpa135 Attachment, motility [132] CpMuc Invasion [133] CpMEDLE-1/2 Invasion [134,135] CpABC Nutrient transport [136] CpATPase1 ...
Reference: Cryptosporidium
