Rui Liang's research while affiliated with Peking University and other places
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Publications (5)
As the building blocks of nucleic acids, nucleotides are conditionally essential nutrients that exhibit multifaceted activities. The present study aimed to evaluate the anti-fatigue effects of dietary nucleotides (NTs) on mice and explore the possible underlying mechanism. Mice were randomly divided into four experimental sets to detect different i...
The goal of the present study was to investigate the wound-healing potential of marine collagen peptides (MCPs) from chum salmon skin administered to rats following cesarean section (CS).
Ninety-six pregnant Sprague-Dawley rats were randomly divided into four groups: a vehicle group and three MCP groups. After CS, rats were intragastrically given M...
To assess the long-term toxicity and carcinogenicity of dietary nucleotides (NTs), Sprague-Dawley rats were administered the NTs for life-through with the dose of 0, 0.01%, 0.04%, 0.16% and 0.64%. With the exception of several groups, the results showed no significant differences in weight gain, clinical symptoms data, blood indicators, and Non-neo...
A pilot-scale production was developed to enhance the value of proteins from corn gluten meal (CGM). Corn protein isolate (CPI) with high protein content (90.68%) was obtained through heat treatment of CGM (150 kg) in aqueous alkaline solution. Two-step enzymatic hydrolysis and multistage separation were applied to enrich corn oligopeptides (COP) w...
We sought to determine whether postcaesarean treatment with whey peptides (WP) affects the healing of skin and uterine incision in rats during puerperium. Forty-eight rats were randomly divided into two groups. After a caesarean section, twenty-four rats were intragastrically administered WP, while others were administered a control vehicle. On day...
Citations
... Additionally, their safety was fully verified by a lifetime feeding experiment and four generation breeding experiment with high safety [15][16][17]. What is more, NTs have been found to have many biological functions, such as anti-aging [18], telomere length regulation [19,20], tumor inhibition [21], immune regulation [22][23][24], anti-inflammatory and antioxidant properties [25,26], learning and memory improvement [27,28], antifatigue [29], liver protection [30,31], intestinal protection [32][33][34], flora regulation [35,36], growth promotion [37,38], neuroprotective effect [39], and participation in one carbon unit metabolism. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/472514582323200-1489667663074_Q64/Junbo-Wang-17.jpg)
... Hydroxyproline was shown to be higher in the collagen-treated group over time than in the control group, indicating that it promotes collagen deposition and consequently healing [29]. Wang et al. [30] reported that oral intake of Chum salmon skin collagen peptides may promote angiogenesis, collagen deposition, and wound contraction, like the experiments discussed above. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/340244927926273-1458132120244_Q64/Ming-Zhao-57.jpg)
... In addition, these hydrolysates not only maintain and often improve their biological value but also possess functional properties that surpass those of the original proteins. The hydrolysates also contain bioactive peptides [25]. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/1114965490573313-1642839896120_Q64/Zhaofeng-Zhang-8.jpg)
... WP intake is beneficial for the experimental recovery of burn injury (Öner et al. 2006) and atopic dermatitis-like skin lesions (Shimizu et al. 2006), just as well as wound healing (Ebaid et al. 2011;Badr 2012;Badr et al. 2012). In addition, Wang et al. (2010) reported that intragastric WP-derived peptide administration increases collagen fiber regeneration in the incised skin after cesarean section and promotes wound closure. While these studies have focused on the efficacy of oral WP administration, the potential topical use of low-molecular-weight WPs (LMWPs), such as α-LA, attracts growing interest in the field of wound healing (Ghosh et al. 2010). ...
