Roxana Doina Trusca's research while affiliated with CSSNT-UPB - Center for Surface Science and Nanotechnology University POLITEHNICA of Bucharest and other places
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Publications (10)
Melissa officinalis is an important medicinal plant that is used and studied intensively due to its numerous pharmacological effects. This plant has numerous active compounds with biomedical potential; some are volatile, while others are sensitive to heat or oxygen. Therefore, to increase stability and prolong biological activities, the natural ext...
Interest to finding a solution to help reduce the cases of microbial infections in wounds is very high. The concern is all the greater as antibiotic resistance has become an increasingly common problem. In order to find a new way to synthesize a wound dressing which has superior prop-er-ties, sodium alginate, hyaluronic acid and silk fibroin functi...
The aim of the present study was to obtain antimicrobial dressings from bacterial cellulose loaded with nutmeg and of fir needle essential oils. The attractive properties of BC, such as biocompatibility, good physicochemical and mechanical stability, and high water absorption, led to the choice of this material to be used as a support. Essential oi...
Two types of mesoporous materials, MCM-41 and MCM-48, were functionalized by the soft-template method using (3-aminopropyl)triethoxysilane (APTES) as a modifying agent. The obtained mesoporous silica materials were loaded with trans-ferulic acid (FA). In order to establish the morphology and structure of mesoporous materials, a series of specific t...
Dense fine-grained Ba0.6Sr0.4TiO3 ceramics with submicronic grains sizes (GS) have been prepared using nanopowders synthesized via sol-gel route and consolidated by Spark Plasma Sintering (SPS). By changing SPS parameters, the GS was reduced from 214 nm to 74 nm. Diffuse ferroelectric-paraelectric phase transitions and low values of dielectric perm...
In this study, two types of mesoporous silica with different pore structures and volumes were synthesized by the soft-templating method. The two types of mesoporous silica, type MCM-41 and MCM-48, were loaded with three polyphenols—caffeic acid, p-coumaric acid and trans-ferulic acid—in the same ratio of mesoporous silica:polyphenol (1:0.4 w/w). Th...
As a third-generation β-lactam antibiotic, cefotaxime shows a broad-spectrum with Gram-positive and Gram-negative bacteria activity and is included in WHO’s essential drug list. In order to obtain new materials with sustained release properties, the present research focuses on the study of cefotaxime absorption and desorption from different functio...
This paper aimed to develop two types of support materials with a mesoporous structure of mobile crystalline matter (known in the literature as MCM, namely MCM-41 and MCM-48) and to load them with gallic acid. Soft templating methodology was chosen for the preparation of the mesoporous structures—the cylindrical micelles with certain structural cha...
Citations
... Various strategies were reported in the literature employing organic [12], inorganic [13], or mixed agents [14]. Inorganic nanoparticles (NPs) represent a special class of antimicrobials that can be used in packaging films; here are worth mentioning ZnO, Ag, CuO, TiO 2, or SiO 2 [15][16][17]. Such innovative antimicrobial biodegradable materials can diminish the microorganisms' proliferation and thus reduce food spoilage, increase shelf life, and help provide better food quality [18][19][20][21][22]. ...
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... Dielectric tunable materials, owing to their nonlinearity of dielectric constants with applied electric fields, are considered to have widespread applications for many electronic tunable devices such as resonators, phase shifters, and tunable filters [1][2][3][4]. To satisfy the requirements of the above devices, dielectrics with large dielectric tunability, low dielectric loss, and high breakdown strength are essential [5][6][7]. ...
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... Mesoporous silica: Mesoporous silica nanoparticles (MSNs) have been extensively studied as carriers because of their biocompatibility, stability, pore size, and surface functionalization, which allow high polyphenol loading (Chircov et al., 2020;Huang et al., 2014). A variety of polyphenols can be loaded into mesoporous silica, which was ascertained using a variety of techniques, including BET, FT-IR, and thermogravimetric analyses (Petrisor et al., 2022). ...
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... As a result, we found that the scaffold we developed released the antibiotic more slowly and for a longer duration. It is thought that a bioeliminable scaffold that offers controlled and slow drug release may be more effective on biofilm and more successful in the treatment of osteomyelitis [27]. ...
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... 28 In this context, it was described that the material acted as an improved antimicrobial agent compared to the free GA. However, studies regarding the various biomedical applications of GA are mainly carried out using GA as a guest within a nanocarrier, 27,30,32,34,35 and rarely an actual GA-silica nanoparticle conjugate is investigated. In relation to oxidative stress management, cancer cells are often characterized by ROS imbalance. ...
