Robert E. Feldmann's research while affiliated with Universität Heidelberg and other places

... Similarly, they also reported enhanced activation of the mPTP in cortical neurons from old rats. Very recently, Gainutdinov et al. [47] also reported that brain mitochondria from old rats exhibited lower ∆Ψm as measured by the quenching of safranine fluorescence, and that brain mitochondria from old rats also exhibited enhanced activation of mPTP. ...

... With the advent of convenient ultrasound technology, the usSGB has emerged as a safer and more effective approach, particularly for patients who have limited mobility. 19 This development opens up the possibility of using ultrasound techniques to serve as an objective measurement tool for assessing the hemodynamic effects of SGB. In 2003, Celiktas et al 20 used color duplex ultrasound to demonstrate that SGB results in dilatation of the artery and a reduction in resistive and pulsatility indices (RI, PI). ...

... The procedure was performed at the bedside at the Cardiac Care Unit using an ultrasound-guided paratracheal approach. Ultrasound was used to visualise critical structures, including the carotid and vertebral arteries, the left jugular vein, the 6th cervical vertebra, the longus colli muscle and the stellate ganglion, in order to reduce the risk of major vascular complications [24]. Direct oral anticoagulants were discontinued 24 h in advance when possible. ...

... This may seem counterintuitive, as EX30 ® is a more rigid material and based on conventional principles, may be expected to demonstrate increased effectiveness especially in posterior regions. This result may be explained by the improvement in clinician skill and aligner biomechanics, and improved comfort with SmartTrack ® aligners, 9,22 resulting in better patient compliance. The apparently improved expression observed with two-week changes in comparison to 1-week changes is attributed to the provision of sufficient time for the bone to remodel before the reintroduction of a new aligner. ...

... SmartTrack ® has been favorably rated in a patient survey as an aligner material that provides more comfort during use, and a significant reduction in pain intensity. 18 The latest improvements in transverse expansion accuracy are credited to the SmartTrack ® aligner material, which in our opinion is an erroneous interpretation of the available evidence, 16 The premise that clear aligners tend to decrease its accuracy as it moves posteriorly is in accordance to our findings in the EX30 ® group. 3,5,17 And in contradiction to our findings for SmartTrack ® aligners, our data has shown an improvement in the accuracy of posterior teeth, with first molars presenting from 67.88 to 83.32% of predicted changes. ...

... The stellate ganglion is a component of the cervical sympathetic chain; it forms via the fusion of the inferior cervical ganglion to the first thoracic sympathetic ganglion at the level 2 of 11 of C7 [7]. The ganglion delivers sympathetic inputs to the ipsilateral upper extremities; thus, stellate ganglion block (SGB) has been used to treat post-stroke CRPS in the upper limbs, leading to improvements in pain, swelling, range of motion, and functional activity [8][9][10]. ...

... One of the influential factors on the quality of life of patients is pain, which leads to considerable physiological and psychological complications for patients (7)(8)(9). Identification of pain prevalence can set the ground for finding suitable palliative interventions including both pharmacological and nonpharmacological interventions (10,11). For pain mitigation, various methods are used. ...

... Using a phantom allows trainees to gain familiarity with targeted ultrasound-guided procedures in a safe environment, 3 and has been shown to improve technical procedural skills, 1,2,4,5 reduce anxiety, 1 improve confidence reduce the risk of potential complications 6 and improve the proficiency of novices undertaking ultrasoundguided procedures. 2,[7][8][9][10][11][12][13][14][15] Unfortunately commercially available ultrasound phantoms are limited by their high cost and may degrade with repeated use. Alternatives such as raw meat work well as phantoms, but contain high levels of bacteria that can represent a health risk when used in clinical environment with Objective: Ultrasound-guided intervention is an essential skill for many radiologists and critical for accurate diagnosis and treatment in many radiology subspecialties. ...