Rhea Edmonds's research while affiliated with University of Southampton and other places

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Publications (1)


(A–C) Cranial CT on the day of admission to neurological ICU showing pansinus thrombosis with accompanying atypical intracranial bleeding (white arrows). (D) Cranial CT showing progression of intracranial bleeding and midline shift despite decompressive hemicraniectomy and external ventricular drainage 7 days after admission (white arrow).
(A, B) CT of the abdomen showing complete portal venous thrombosis and thrombosis of mesenteric veins (white arrows). (C) Doppler and duplex sonography showing a 3‐level deep vein thrombosis of the left leg (white arrow). (D) Cranial MRI showing a small cavernoma but no other relevant pathology (white arrow).
Follow up of PAA status, platelet count and OD anti‐PF4/Heparin IgG ELISA after discharge.
Vaccine‐induced immune thrombotic thrombocytopenia (VITT) after SARS‐CoV‐2 vaccination: Two cases from Germany with unusual presentation
  • Article
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January 2023

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72 Reads

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3 Citations

Clinical Case Reports

Clinical Case Reports

Rhea Edmonds

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Sunke Habben

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Vaccine‐induced immune thrombotic thrombocytopenia (VITT) is a rare clinical condition that has emerged during the mass immunization against SARS‐CoV‐2. Reports indicate that VITT may also be induced by other vaccines, such as the human papillomavirus vaccine, or occur independently of vaccination. Its recognition requires a high index of suspicion, especially in patients presenting with thrombocytopenia and thrombosis several days after vaccination with an adenoviral vector‐based vaccine against SARS‐CoV‐2. Bleeding manifestations do not exclude VITT, as initially assumed. It is of great importance to perform the appropriate diagnostic tests early in the course of the disease, as false‐negative results may occur and many aspects of VITT are not fully understood. These two cases from Germany demonstrate unusual presentations of VITT.

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