ROY SHALIT's research while affiliated with Sheba Medical Center and other places
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Publications (7)
Background: Advanced hybrid closed loop (AHCL) algorithm combines automated basal rates and corrections yet requires meal announcement for optimal outcomes. We aimed to compare the performance of the MiniMed™ 780G AHCL algorithm with and without meal announcement. Methods: In a single-arm study involving 14 adults with type 1 diabetes (T1D), we eva...
Background: Carb-counting is a significant burden for persons with diabetes who require insulin to mitigate postprandial hyperglycemia. A closed-loop (CL) system with auto meal-bolus that eliminates manual mealtime bolusing was studied in adults with T1D.
Methods: The system included the MiniMed™ 780G pump and a smartphone-paired smartwatch with th...
Background and Aims: Meal management is a major challenge for people with type 1 diabetes (PWD) . We aimed to explore 3 approaches to complex meal planning, from a most comprehensive scheme in open loop (OL) to a simplified, carbohydrate (CHO) counting-free scheme when using the MiniMed™ 780G system AHCL.
Methods: Participants (N=13, mean age 46.8±...
Background: We compared glycemic outcomes and participant experience during MiniMed™ 780G Advanced Hybrid Closed Loop (AHCL) system use while announcing all meals vs. announcing meals at will.
Methods: Participants with T1DM used the AHCL system at home during two 90 days phases in which they were given instructions first to announce all meals (AM)...
Objective: Seizures following administration of potent bisphosphonates have been reported only sporadically in medical literature. The rare cases described were often attributed to other precipitating factors such as hypoglycemia, acute infection or predisposition to post-bisphosphonate hypocalcemia. We review the previous cases and present a new c...
Background and Aims: Advanced Hybrid closed loop (AHCL) algorithm combines automated basal rate with additional enhancement when a rise in glucose level is detected. This study assessed the effectiveness and safety of AHCL with unannounced meals.
Methods: Fourteen participants were using Medtronic AHCL system at home for a mean of 72.6 days. Each p...
Introduction: Although potential risk of DKA, ketogenic diet became popular among T1DM patients as proven to reduce the incidence of hypoglycemia, glycemic variability, and HbA1c (1).
Severe carbohydrate restriction had not been included among DKA precipitating factors in pregnancy since a minimum consumption of 175 g of carbohydrates a day is reco...
Citations
... Therefore, training from health care professionals (HCPs) is required for the PWD for optimal use of these AID systems, including specific differences that exist between these various systems. Studies have revealed that unannounced meals 13,14 and situations involving rapid changes in insulin requirements are a challenge. 15 The AID systems offer some user-initiated adjustments, which can be crucial for overcoming rapidly changing insulin resistance. ...
... [8][9][10] Overall, five cases of seizures occurring soon after BP administration have been reported. 11 One case reported a seizure in an 87-year-old man with metastatic prostate cancer receiving ZA, with the patient's symptoms normalising rapidly after correction of serum calcium levels. 9 In another case, an 80-year-old woman suffering from post-menopausal osteoporosis developed a hypoglycaemic seizure 30 minutes after the infusion. ...