Pushpani Herath's research while affiliated with Australian National University and other places

... The searches produced 527 articles in total for screening (figure 1), of which 340 came from a formal database and 187 came from the grey literature. Of the database articles, 45 were read in full to assess for eligibility, and eight dementia prevention reviews (7,(14)(15)(16)(17)(18)(19)(20) were included. We included four (21-24) (Google search n=3, NICE search n=1) articles from the grey literature. ...

... Metformin (1,1-dimethylbiguanide hydrochloride) has been widely used as blood glucose-lowering by inhibiting gluconeogenesis in treatment of type 2 diabetes mellitus (T2DM) patients for 60 decades 22 . Notably, metformin has been shown to have pleiotropic activities against cancer 23 , inflammatory 24 , and also possesses a neuroprotective activity 25 . Interestingly an in vivo study showed that metformin potentially lowers the risk of severe dengue among diabetes patients that use metformin users when compared to non-users 26 . ...

... In addition, they target mid to late-life adults often at an increased risk of developing dementia (e.g., with existing cognitive decline, a family history of dementia, or cardiovascular comorbidities) [8]. Our research team developed and evaluated the first clinical trial to utilize online educational modules as part of the dementia risk reduction intervention [12]. This study found that including a face-to-face component to accompany online modules did not significantly increase intervention efficacy or adherence. ...

... It assesses 11 risk and 4 protective factors for AD and has been validated on three independent cohorts against the Cardiovascular Risk Factors, Aging, and Dementia index. It has been recognized as a primary risk assessment tool in large-scale AD prevention trials (Anstey et al., 2014) and has been utilized in an online AD risk reduction trial in Australia . This tool, which can be administered by healthcare professionals or researchers, enables the assessment of a person's risk of developing dementia and facilitates the provision of targeted interventions to mitigate that risk. ...

... The questionnaire consisted of multiple-choice and open-ended questions aiming to inform the development of a novel dementia risk reduction intervention. Questions related to technology and online learning were informed by our team's extensive experience with digital components of dementia risk reduction interventions (e.g., [12,42,43]). This experience helped to streamline question response options to keep them concise, while the inclusion of 'other' as an open-ended response ensured comprehensive data collection and minimized the risk of bias or incomplete answers. ...

... Therefore, risk personalization for all known modifiable risk and protective factors needs to be further investigated. In the case of dementia, composite modifiable risk scores such as the LIfestyle for BRAin Health (LIBRA) index 8,17 or the Australian National University Alzheimer's Disease Risk Index (ANU-ADRI 18 ) are also relevant to consider due to the syndrome's multifactor etiology. 19,20 These composite risk scores combine the presence or absence of multiple factors into one numeric value that expresses dementia risk. ...

... Patients with CKD should be prepared to pay a considerable amount of money out of pocket for prescriptions [27] because chronic disease management is expensive [28][29][30]. CKD is associated with poverty and other social determinants of health (SDoH), such as social environmental stressors and psychological factors [31]. Financial problems can be linked to physical health, mental health, satisfaction with social activities and relationships, and a declining quality of life [32]. ...

... Patient aggression in general practice can include acts of incivility (hostility, general rudeness and disrespectful behaviour) and violence (physical and sexual abuse) directed towards clinicians and support staff. 8 General practice receptionists experience disproportionately more acts of patient aggression compared with their clinician and practice colleagues, 8 with anecdotal evidence that the COVID-19 pandemic has exacerbated this phenomenon. 9 Despite recognition that every human should be afforded a safe workplace free from physical or psychological harm, 10 there is presently little understanding of how patient aggression is experienced by general practice receptionists, what the impacts are on this group of workers and what support is provided to them to reduce risks and manage the impacts of such acts directed towards them. ...

... Additionally, those who had fewer years in practice were more likely to experience verbal abuse than those with more experience; in the present study, those who had 6 to 10 years of experience had the highest exposure to verbal violence. [26] In this study, according to the HCWs, the offending persons were mostly the patients and their relatives. This is consistent with the findings of Abed et al [8] and some other studies. ...