Patrycja Jastrząb's research while affiliated with Medical University of Bialystok and other places
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Publication (1)
Simple Summary
The aberrant sialylation of membrane glycocalyx plays a pivotal role in the regulation of malignant cell behavior and correlates with a worse prognosis and shorter overall survival for patients. The biological and physical properties of sialome determine the negative charge and high hydrophilicity of cell membranes and thereby regula...
Citations
... The negative charge carried by sialic acids (so-called sialome) on the surface of cells contributes to the surface's hydrophilicity and affects the cellular adhesion and metastatic potential of cancer cells [44]. Exosomes as small extracellular vesicles are known not only to modulate the primary tumour site but also to interact with a pre-metastatic niche [45]. ...