Mingyang Sun's research while affiliated with China Academy of Traditional Chinese Medicine and other places

Publications (7)

Article
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Derived from hazelnuts, hazel leaf has been utilized in traditional folk medicine for centuries in countries such as Portugal, Sweden, and Iran. In our previous investigations, we conducted a preliminary assessment of the hazel leaf polyphenol extract (referred to as ZP) and identified nine compounds, such as kaempferol and chlorogenic acid, in its...
Article
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(1) Background: Solanum nigrum L. is a plant of the genus Solanum in the family Solanaceae and is commonly used to treat tumors. Solasonin (SS) is a steroidal alkaloid extracted from Solanum nigrum L. that has anti-colorectal cancer (CRC) activity. (2) Methods: Column chromatography, semi-preparative HPLC and cellular activity screening were used t...
Article
Nonalcoholic fatty liver disease (NAFLD) is a common condition that is prevalent in patients who consume little or no alcohol, and is characterized by excessive fat accumulation in the liver. The disease is becoming increasingly common with the rapid economic development of countries. Long-term accumulation of excess fat can lead to NAFLD, which re...
Article
Full-text available
Ginsenoside CK is the main metabolite of protopanaxadiol saponins in intestinal bacteria. Previous studies have shown that ginsenoside CK can affect many aspects of tumor development through a variety of mechanisms. However, few studies have reported the antimetastatic effects of ginsenoside CK in non-small-cell lung cancer (NSCLC). In this study,...

Citations

... Hazelnuts are widely used in food products due to their flavor, texture, and high nutritional value, including proteins, monounsaturated fatty acids, fibers, vitamins, and bioactive compounds [1]. Hazelnuts are recommended in moderate doses as a healthy nut because their components, such as monounsaturated fatty acids, fibers, and antioxidants, contribute to the prevention of cardiovascular diseases [2], reduction in cholesterol [3], improvement in the lipid profile, and combating of oxidative stress, as well as having anti-inflammatory, neuroprotective, and anticancer properties [4]. In Portugal, hazelnut production is vital for the rural economy, and has been the subject of research to improve production and processing in the sector [5]. ...
... These considerations make tackling NAFLD a formidable challenge, and the interventions and chemicals employed for clinical trials are also with little success. Encouragingly, armed with the advantage of high efficacy and low toxicity, natural products have increasingly gained attention as potential therapeutic agents for the treatment of NAFLD [5]. Natural products have served as a vast platform for the development of safe and cost-effective drugs or supplements. ...
... The Western blot assay method is consistent with our previous report [41]. Cells or renal tissue were collected and lysed in cell lysis buffer (provided by Beyotime Biotechnology, Nantong, China) while maintaining a low temperature on ice. ...