Michael J. O'Dea's research while affiliated with Mayo Clinic - Rochester and other places
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Publications (8)
Between 1950 and 1970, 44 patients (2.5 per cent) with renal cell carcinoma and a solitary metastatic lesion were treated at our clinic. Generally, treatment was aggressive, involving nephrectomy and excision of the metastatic lesion when possible. Patients presenting with the primary and metastatic lesion at the same time did not do as well as pat...
Between 1950 and 1970, 44 patients (2.5 per cent) with renal cell carcinoma and a solitary metastatic lesion were treated at our clinic. Generally, treatment was aggressive, involving nephrectomy and excision of the metastatic lesion when possible. Patients presenting with the primary and metastatic lesion at the same time did not do as well as pat...
A study of 5 patients with tuberculosis prostatitis revealed that (1) there is a greater chance of striking a noncaseating granuloma than a caseating lesion by needle biospy when both are present; (2) the absence of caseation on biopsy does not necessarily rule out tuberculosis; and (3) special stains may be negative for tuberculosis because of the...
The records of 34 patients who underwent ureterosigmoidostomy after pelvic irradiation were reviewed and the incidence of complications was found to be similar to that in other series of ureterosigmoidostomy without prior irradiation. No difference was established between the use of linac or cobalt 60 therapy in relation to postoperative complicati...
Between 1963 and 1972, 86 patients with non-specific granulomatous prostatitis were seen. Symptomatology was suggestive of a lower urinary tract infection in the majority of the cases. The most important feature on prostatic examination was the likelihood of confusion with prostatic carcinoma. The benign course is in marked contradistinction to car...
The symptoms and physical findings in patients with transitional cell carcinoma of the prostate were similar to those in patients with prostatic adenocarcinoma. Usually the neoplasm was poorly differentiated and advanced when the diagnosis was first established. Osseous metastases were commonly osteolytic. Frequently, elevations of serum alkaline o...
At the Mayo Clinic, from 1940 through 1974, 21 patients have undergone nephropexy for nephroptosis. Fourteen of the 16 patients with long-term follow-up were cured; 2 of the 16 patients were partially relieved. An additional 2 patients who had one-year follow-up examinations were asymptomatic. Three patients were lost to follow-up. In this series r...
Citations
... Paired organs have one feature in common; they can be affected by exactly the same carcinogenic influences, both genetic and environmental [1] Understanding the risk of bilateral kidney cancer is particularly relevant because the function of this organ is vital and removal of the remaining kidney as a result of bilateral cancer may require life-long hemodialysis [2,3]. Hence if patients at high risk of developing bilateral metachronous kidney cancer could be identified early, a longer and more intensive followup schedule would be undertaken, with the advantage of earlier cancer identification [4]. Bilateral renal tumours are although not common but not rare. ...
... The diagnosis of TP is based on finding a caseating lesion or using special stains (auramine rhodamine) on the biopsy specimen, but there is a greater chance of sampling a non-caseating granuloma than a caseating lesion by needle biopsy when both are present, and special stains might be negative for tuberculosis because of the smallness of the tissue sample. Therefore, the absence of caseation on biopsy does not necessarily exclude tuberculosis, and if the clinical suspicion of TP is high, and if noncaseating lesions are found on needle biopsy, a second biopsy specimen should be taken for culture only [19]. Miralles et al. [8] proposed that when inflammation is slight, phagocytosis is absent, and caseous necrosis is present, TP should be suspected. ...
Reference: Granulomatous prostatitis
... Although RCC can metastasize to almost every organ, the most common metastatic sites are the lungs, abdomen, bones and brain [3]. In addition to being able to metastasize to numerous different organs, RCC can recur or metastasize many years after resection of the primary tumor [4]. ...
... Granulomatous prostatitis (GP) is a self-limited inflammatory process, which most frequently presents with low-grade fever, dysuria, and frequency. [1,2] the prostate. [3][4][5] Morphologically, NSGP is a diffuse, chronic inflammation associated with focal necrosis and multinucleated giant cells in the absence of acid-fast bacteria or other special microorganisms, and without relationship to previous transurethral resection of the prostate (TURP) or systemic granulomatous disease. ...
... The kidney was fixed to the front lateral side with 2/0 non-absorbable suture starting the stitching from the upper to the lower pole of the renal capsule. Each suture was passed through the renal parenchyma itself kidney due to the high invasiveness of the available methods compared to the severity of the symptoms (2)(3)(4)(5). The procedure requires a large incision in the skin and division of multiple muscle layers. ...
... 5 No evidence of glandular structure is demonstrated and cell spindling is often a prominent feature. 3 The majority of tumors exhibit moderate to poor differentiation of architecture. Broders' grade 3 is the most common grade identified. ...
... [1] Formation of vesical calculi on the suture material which was used for ureteroneocystostomy has been reported in the past. [2][3][4] Ureteroneocystostomy is one of the important steps in the surgical procedure of renal transplantation. Any technical fault can lead to urinary leak, ureteric obstruction, or vesicoureteral reflux which results in increased morbidity or even graft loss. ...
