Michael H. Entrup's research while affiliated with Tufts University and other places
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Publications (7)
Specific technical problems are associated with the management of patients who have either of the two types of right-sided arches and aneurysms of the aortic arch and descending aorta. Two different approaches to addressing these problems, depending on the predominant congenital vascular anatomy, are presented.
To determine the optimal method of brain protection during deep hypothermic circulatory arrest (DHCA) for arch repair.
Of 139 potential aortic arch repairs (denominator), we randomized 30 patients to either DHCA alone (n = 10), DHCA plus retrograde brain perfusion (RBP) (n = 10), or antegrade perfusion (ANTE) (n = 10); a further 5 coronary bypass (...
Mammals regulate body temperature by regulating heat content and distribution (1). To maintain a constant heat content, heat gain or metabolic heat production must equal heat loss. When heat gain or metabolic heat production exceeds heat loss, the total heat content of the body increases, resulting in an increase in mean body temperature. Conversel...
Of all aortic operations, thoracoabdominal aortic repairs have the highest risk of spinal cord neurologic injury, manifest by lower limb paraplegia or paraparesis. Cerebrospinal fluid drainage combined with intrathecal papaverine (CSFDr + IP) may reduce the risk and severity of neurologic injury. The objective of this study was to evaluate the effe...
Background. Of all aortic operations, thoracoabdominal aortic repairs have the highest risk of spinal cord neurologic injury, manifest by lower limb paraplegia or paraparesis. Cerebrospinal fluid drainage combined with intrathecal papaverine (CSFDr + IP) may reduce the risk and severity of neurologic injury. The objective of this study was to evalu...
A 68-year-old patient presented with an extensive aortic aneurysm extending from the aortic valve to the aortic bifurcation associated with severe continuous pain, dysphagia, and hoarseness. Because of the risk of impending rupture and an "elephant trunk" procedure not being an option, the entire aorta from the aortic valve to the aortic bifurcatio...
An overview of several perioperative complications and their management strategies is presented. Operative hypothermia, malignant hyperthermia, bronchospasm, and side effects of spinal opioid agents are discussed. Ramifications of these complications may extend well beyond the operative period and influence patient outcome. Therefore, it is necessa...
Citations
... In case of loss of these potentials, intercostal arteries are reimplanted and higher blood pressure levels are achieved. (8)(9)(10) All these end-organ protective adjuncts to the "inclusion technique" represent essential tools for the modern management of TAAA to minimize renal, mesenteric, and spinal cord ischemia. ...
... adept at treating complex aortic disease, thereby making surgical treatment more suitable for higher-risk patients. [12][13][14][15] We have previously described our endovascular and hybrid treatment strategies with minimal postoperative complications, including frozen elephant trunk (ET) repair and thoracic endovascular aortic repair (TEVAR). 8 Here, we present a large cohort of open surgical, endovascular surgical, and nonoperated patients with KD and report our outcomes in the patient groups. ...
Reference: Outcomes of Repair of Kommerell Diverticulum
... In our center, a number of patients were operated on such that entire aortas were replaced during a single operation, with a mortality rate of 17% (14). Though it was feasible and could be done, this high mortality rate was a problem. ...
... 30 Level B evidence indicates moderate-quality evidence from one or more RCTs. Three RCTs have been published to date outlining the utility of prophylactic CSF drainage in open thoracoabdominal aortic aneurysm repair [31][32][33] ; however, no RCTs have yet been published on the endovascular approach. High volume center (50 or more) À1 ...
... Neurocognitive function after straight DHCA was explored by Chau et al. in 33 patients who did not need DHCA and 29 who did [66] . The prevalence of patients who showed some cognitive decline was not related to DHCA (13/33 vs. 11/29, P = 1.00). ...