Meiqi Cheng's research while affiliated with Shandong University and other places
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Publications (6)
The clinical treatment of infected skin injuries caused by exogenous bacteria faces great challenges. Conventional therapeutic approaches are difficult to achieve synergistic effects of infection control and induction of skin regeneration. In this study, a novel tannic acid-based physically cross-linked double network hydrogel (PDH gel) was prepare...
Marine shell resources have received great attention from researchers owing to their unique merits such as high hardness, good toughness, corrosion resistance, high adsorption, and bioactivity. Restricted by the level of comprehensive utilization technology, the utilization rate of shells is extremely low, resulting in serious waste and pollution....
The formation of nacreous layers of abalone shell (Aba) is a similar process to the deposition of calcium salts in human bone, with the main mechanism being the orderly mineralization of inorganic matter mediated by organic bioactive components. In this study, 3D printing technology was employed to use the abundant calcium sources and bioactive sub...
Marine polysaccharides (MPs) are an eco-friendly and renewable resource with a distinctive set of biological functions and are regarded as biological materials that can be in contact with tissues and body fluids for an extended time and promote tissue or organ regeneration. Skin tissue is easily invaded by the external environment due to its softne...
Citations
... The antibacterial mechanism of the hydrogel mainly depended on the synergistic effect of TA and Fe 3+ (Fig. 5b). The existence of hydroxyl groups of TA in CTFG hydrogels bound to the sulfhydryl groups (-SH) present in proteins both inside and outside the cell membrane through non-covalent bonds, thereby disrupting the integrity of the cell membrane and inhibiting the proliferation of anaerobic bacteria [41]. Meanwhile, Fe 3+ can be absorbed by bacteria, and the reduced Fe 2+ could generate abundant hydroxyl radicals (-OH), leading to lipid peroxidation of the cell membrane, impeding protein, and even resulting in cell death [42]. ...
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... The organic matter-which includes proteins, glycoproteins, chitin, and polysaccharides-plays a crucial role in biomineralization [25]. An oyster shell contains a water-soluble matrix, which exhibits osteoinductive and antibacterial characteristics [26][27][28][29]. ...
... The results showed that the incorporation of nano-HA and carbon fiber increased the tensile modulus and strength, and demonstrated higher cell attachment, proliferation and osteogenic differentiation than those of PEEK. Another method is to perform surface treatment for cell attachment and proliferation [21], including surface porous [22][23][24] and overall porous [25][26][27][28] PEEK and its composites. The overall porous PEEK exhibits increased bioactivity; however, its strength decreases by 86 % owing to the high overall fraction of porosity and weak local bonds formed during powder sintering [29,30]. ...
... implantation of a scaffold into the affected area, it should furnish structural support for cell 129 adhesion, proliferation, migration, and differentiation, facilitating cellular activity akin to the in- ...
