Madhukar A. Pathak's research while affiliated with Harvard Medical School and other places
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Publication (1)
The therapeutic uses of naturally occurring psoralens in modern-day medicine (8-methoxypsoralen (8-MOP), 5-methoxypsoralen (5-MOP), 4,5',8-trimethylpsoralen, and a few other synthetic psoralens) have evolved through five stages of development. (1) In the historical period (2000 BC to 1930 AD), the pigment-stimulating properties of naturally occurri...
Citations
... Phototherapy using furocoumarins, such as psoralen (linear furocoumarin) and angelicins and allosporalens (angular fuorocoumarins) (Fig. 1), have been extensively known and utilized (Pathak and Fitzpatrick 1992;Melough et al. 2018). The phototherapeutic activity of these compounds arises mainly from their ability to form adducts with the pyrimidine bases of DNA (Seret et al. 1992). ...
