January 2011
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263 Reads
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6,057 Citations
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Publications (1)
Citations (1)
... 40 In 2011, the National Institute on Aging and the Alzheimer's Association (NIA-AA) published separate recommendations for the diagnosis of AD in its preclinical, MCI, and dementia states. [41][42][43] These criteria also proposed a model of the pathophysiological sequence of AD, of which Aβ accumulation is an "upstream" event in the cascade leading to the "downstream" synaptic dysfunction, neurodegeneration, and eventual neuronal loss. In 2018, the NIA-AA further categorized biomarkers into Aβ deposition, pathologic tau, and neurodegeneration [AT(N)]. ...
- Citing Article
January 2011