Lu Zhang's research while affiliated with Peking Union Medical College Hospital and other places
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Publications (3)
Background:
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disorder in the central nervous system (CNS) with distinct clinical, radiological, and pathological characteristics. The pathophysiology of CLIPPERS still remains unclear. Because a few cases about lymphoma mimick...
Background:
We studied patients with chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) associated with or without lymphoma and measured risk factors suggestive of an underlying lymphoma and follow-up outcomes.
Methods:
CLIPPERS patients associated with or without lymphoma were included into...
Rationale:
Concomitant cryoglobulinemic vasculitis and cold agglutinin disease (CAD) is an extremely uncommon clinical scenario. The role of bortezomib in the treatment of cryoglobulinemic vasculitis needs further investigation.
Patient concerns:
A 72-year-old Chinese woman presented with a 25-year history of cyanosis of the extremities after co...
Citations
... 3,5 To find previous lymphoma-associated cases up to November 2023, PubMed and Scopus online databases were searched using the keywords "CLIPPER" and "Lymphoma". To the best of our knowledge, 20 patients with lymphoma-associated CLIPPERS have been reported [6][7][8][9][10][11][12][13][14][15][16] since the first introduction of CLIPPERS. 2 A review of 10 patients by Zhang et al. showed that patients with lymphoma-associated CLIPPERS had worse clinical outcomes and higher risk of mortality compared to those without lymphoma. ...
... 3,5 To find previous lymphoma-associated cases up to November 2023, PubMed and Scopus online databases were searched using the keywords "CLIPPER" and "Lymphoma". To the best of our knowledge, 20 patients with lymphoma-associated CLIPPERS have been reported [6][7][8][9][10][11][12][13][14][15][16] since the first introduction of CLIPPERS. 2 A review of 10 patients by Zhang et al. showed that patients with lymphoma-associated CLIPPERS had worse clinical outcomes and higher risk of mortality compared to those without lymphoma. ...
... Bortezomib is administered intravenously or subcutaneously at a starting dose of 1.3 mg/sqm on 21-day cycles: twice weekly for 2 weeks (days 1, 4, 8 and 11) followed by a 10-day rest period (days [12][13][14][15][16][17][18][19][20][21]. After eight cycles, a maintenance schedule can be followed, that is, once weekly for 4 weeks (days 1, 8, 15 and 22) followed by a 13-day rest period (days [23][24][25][26][27][28][29][30][31][32][33][34][35]. Pharmacodynamic parameters are similar with subcutaneous or IV administration. ...
