Lisa A. Marks's research while affiliated with Mayo Foundation for Medical Education and Research and other places

Publications (37)

Article
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Background Unlike acute rhinosinusitis (ARS) which is mostly viral in etiology, the role of viruses in chronic rhinosinusitis (CRS) remains unclear. Viruses may play a role in initiation, exacerbations or perpetuate chronic inflammatory responses in the sinonasal mucosa. Research needs to characterize whether viruses are part of the normal sinonasa...
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Objective The objective of this study was to critically assess current evidence regarding the role of prophylactic antiseizure medication in patients presenting with acute intracerebral hemorrhage (ICH). Methods The objective was addressed through the development of a structured critically appraised topic. This included a clinical scenario with a...
Article
Background: Pollen is a key source of aeroallergens responsible for allergic rhinitis, conjunctivitis, and asthma. Objective: The goal of this scoping review was to summarize current available literature on the factors that affect pollen counts, allergenicity, and thresholds that induce symptoms in individuals who were sensitized. Methods: Several...
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Background Epigenetics facilitates insights on the impact of host environment on the genesis of chronic rhinosinusitis (CRS) through modulations of host gene expression and activity. Epigenetic mechanisms such as DNA methylation cause reversible but heritable changes in gene expression over generations of progeny, without altering the DNA base-pair...
Article
KEY POINTS There is no consensus on the extent of appropriate surgery for chronic rhinosinusitis (CRS), particularly CRS without polyps (CRSsNP). There is wide heterogeneity in the definition of “limited” and “extensive” endoscopic sinus surgery (ESS). Studies on the appropriate extent of surgery for CRS are needed.
Article
In 2022, a benchmarking survey was completed to gage learner satisfaction with library services, spaces, and resources across 10 Mayo Clinic Libraries. The discussion for this project began around a previously published survey of what medical students wanted from their library. Librarians were asked if Mayo Clinic Libraries could do a similar surve...
Article
Background: Biological sex is increasingly recognized as a critical variable in healthcare. We reviewed the current literature regarding sex-based differences in rhinology to summarize the data and identify critical knowledge gaps. Methods: A scoping review was conducted. Publications reporting sex-based differences in anatomy, physiology, and p...
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Background: The clinical benefit of intravenous immunoglobulin (IVIG) in adult individuals with neuroinvasive West Nile virus (niWNV) infection is not well substantiated. We sought to critically assess current evidence regarding the efficacy of IVIG in treating patients with niWNV. Methods: The objective was addressed through the development of...
Article
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Lymphovenous anastomosis (LVA) is a microsurgical treatment for lymphedema of the lower extremity (LEL). This study systematically reviews the most recent data on outcomes of various LVA techniques for LEL in diverse patients. Methods: A comprehensive literature search was conducted in the Ovid MEDLINE, Ovid EMBASE, and Scopus databases to extrac...
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Background Chronic rhinosinusitis with nasal polyposis is associated with a significant disease burden. The optimal use and administration route for intranasal corticosteroids (INCS) when managing CRSwNP are unclear. Objective To systematically synthesize the evidence addressing INCS for CRSwNP. Methods We searched MEDLINE, EMBASE, and CENTRAL fr...
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Background: Combined PD-1/PD-L1 and CTLA-4 immune checkpoint inhibition for the has been shown to produce superior results in the treatment of malignant melanoma when compared to monotherapy. However, patients with intracranial disease were excluded from these studies given their poor prognosis. Objective: The objective of this study was to crit...
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Purpose: Use of the electronic health record (EHR) during face-to-face clinical encounters affects communication, and prior research has been inconclusive regarding its effect. This survey study assessed health care practitioner use of EHR-specific communication skills and patient and practitioner experiences and attitudes regarding EHR use during...
Article
Multicancer early detection panels (MCEDs) have recently become available to patients with a provider's prescription and an out-of-pocket fee. Beyond theoretical modeling, little is known about how these assays will impact primary care practices despite a high likelihood that primary care providers (PCPs) will be ordering these tests with some freq...
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Objectives Hereditary hemorrhagic telangiectasia (HHT) is a common inherited condition characterized by mucosal telangiectasias, recurrent epistaxis, and arteriovenous malformations. HHT results in detriment to quality of life. Morbidity and mortality result from severe anemia. Conventional interventions for HHT-related epistaxis include nasal pack...
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Objective: To characterize a clinical triad of symptoms associated with myeloid sarcomas of the temporal bone via a review of all previously reported cases. Methods: Case report and Ovid MEDLINE database literature review. Results: A literature search revealed that a clinical triad of hearing loss, otalgia, and facial nerve weakness are common...
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Background: Functional movement disorders (FMD, aka psychogenic movement disorders) are very common and frequently chronic and disabling. Despite this, there is a paucity of evidence-based treatment to manage and alleviate these conditions. Specialized physical therapy (PT), involving sequential motor relearning and redirecting attention, has show...
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Background Persistent monoarthritis in otherwise well-controlled rheumatoid arthritis presents a therapeutic challenge. Intra-articular (IA) steroids are a mainstay of treatment, though some have queried whether IA disease modifying anti-rheumatic drugs (DMARD) and biologics can be used in those who fail steroid injections. Methods A systematic li...
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Background: High-dose chemotherapy followed by autologous stem cell transplantation (HD-ASCT) is a promising alternative to whole brain radiation therapy (WBRT) in the treatment of primary central nervous system lymphoma (PCNSL). The objective of this study was to critically assess current evidence supporting the use of HD-ASCT as first-line conso...
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Background: Stroke is a leading cause of disability worldwide. Selective serotonin reuptake inhibitors are often prescribed following stroke due to high rates of depression. Interest in selective serotonin reuptake inhibitor use for poststroke motor and functional recovery was generated after the publication of the Fluoxetine for motor recovery af...
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Background: There is considerable controversy surrounding the optimal use of sedation in patients with acute ischemic stroke undergoing mechanical thrombectomy. Several retrospective studies have favored conscious sedation (CS) over general anesthesia (GA) in terms of functional outcomes and mortality. Recent data from randomized controlled trials...
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Objective Hemifacial atrophy (HFA) is a rare disorder characterized by progressive unilateral wasting facial soft tissue, muscle, and/or bone. Trigeminal nerve abnormalities may contribute to or result from disease pathophysiology. We aimed to gain further insights into the role of trigeminal pathophysiology along the HFA severity spectrum. Method...
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Aim: To identify the appropriate methods of synovial fluid (SF) specimen storage, manipulation and handling for crystal associated arthritides (CAA) diagnosis. Method: A systematic literature review was conducted using 5 medical databases to identify diagnostic studies assessing SF specimen handling for calcium pyrophosphate (CPP) and monosodium...
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Purpose Gastroesophageal reflux disease (GERD) has been associated with head and neck cancer (HNC), including laryngeal and pharyngeal anatomical sites. A systematic review and meta-analysis was performed to examine these associations. Methods Articles were retrieved from the Medline, Web of Science, Scopus, and Embase databases using keywords “ga...
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Objectives To address concerns related to the safety profile of both Food and Drug Administration (FDA)–approved and non-FDA-approved intranasal corticosteroid (INCS) use in the pediatric population. Data Source Systematic review of MEDLINE, PubMed, and EMBASE databases using comprehensive search strategy, including all INCS formulations and adver...
Article
Background: Noninvasive neuromodulation devices have been used for a variety of headache disorders, including cluster and migraine, since recently being cleared by the Federal Drug Administration. Although these devices have been touted as low-risk options for improved headache control, the data behind actual efficacy endpoints remain unclear. Ob...
Article
Objectives To address concerns related to the safety profile of both Food and Drug Administration (FDA)–approved and non–FDA-approved intranasal corticosteroid (INCS) use in the adult population. Data Source Systematic review of MEDLINE, PubMed, and EMBASE databases using a comprehensive search strategy including all INCS formulations and adverse...
Article
1. What is the clinical question? What combination antithrombotic therapy is recommended for patients with atrial fibrillation with acute coronary syndrome or patients undergoing percutaneous coronary intervention? 2. What does the evidence say? Double therapy (DT) with clopidogrel and direct oral anticoagulants (specifically, dabigatran, rivaroxab...
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The nonpharmacologic management of irritable bowel syndrome focuses on dietary modification through the concept of food sensitivity or intolerance. Currently, testing for food allergies is not recommended in the absence of a clinical history consistent with an immunoglobulin E-mediated reaction. Objective means of determining food sensitivity, such...
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Leveraging an established evidence-based practice (EBP) workshop at the Mayo Clinic campus in Arizona, the manager of Nursing Research asked local library staff to discuss the research process and to demonstrate to the attendees how to use literature databases to support their research projects and EBP practices on their units. The EBP workshop was...
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INTRODUCTION Acute portal vein thrombosis (PVT) is a rare diagnosis frequently associated with cirrhosis. Clinical presentation is typically nonspecific with potentially catastrophic short-term complications including sepsis, bowel infarction, and death. Management strategies differ for acute and chronic PVT. Guidelines for treating acute PVT recom...
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Objectives: (1) To perform a systematic literature review to evaluate associations between post-dural puncture headache (PDPH) and opening pressure (OP), closing pressure (CP), and volume of cerebrospinal fluid (V) removed. (2) To perform a case-control study to evaluate pressure-volume index (PVI) as a novel risk factor for PDPH. Background: Ac...
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Full-text available
Background: Health sciences libraries are being closed or are under threat of closure, but little is published that looks at context and causes or alternative library service delivery models such as affiliations or consolidations. There is also very little research about the effect of these changes on health care provider satisfaction, patient car...
Article
Background: Eosinophilic esophagitis (EoE) is a chronic, inflammatory disease of the esophagus which currently requires repeated endoscopic biopsies for diagnosis and monitoring as no reliable non-invasive markers have been identified. Objective: To identify promising minimally-invasive EoE biomarkers and remaining gaps in biomarker validation....
Article
Full-text available
Background: Millions of people with chronic illness suffer from fatigue. Fatigue is a complex, multidimensional symptom with poorly understood causes, wide variations in severity among individuals, and negative effects on multiple domains of daily life. Many patients with fatigue report the use of herbal remedies. Ginseng is one of the most widely...

Citations

... Pollen, primarily produced by wind-pollinated plant species, is a major source of inhaled allergens. It is estimated that 10 to 30 percent of the global population suffers from seasonal allergic rhinitis and 300 million people suffer from asthma related to airborne pollen (Haahtela et al., 2013;Jyothirmayi and Kumar, 2019;Lopez-Santamarina et al., 2021;Brake et al., 2023). A high pollen load in the atmosphere has been linked to the prevalence of sensitization to aeroallergens in populations (Smith et al., 2014;Zwick et al., 1991;Beutner et al., 2021;Singh and Kumar, 2022). ...
... The Beijing Chaoyang Hospital's Ethics Committee's Institutional Review Board (No. 2020-3-16-18 and date of approval: 2020- [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] gave its approval to this work. All experiments involving human participants adhered to the institutional ethical guidelines and followed the principles of the Declaration of Helsinki. ...
... These approaches are driven by novel theories that integrate anatomical and inflammatory concepts (i.e., the mucosal concept), aimed at enhancing comprehension and management of the CRSwNP disease [18]. Although E-FESS has often been described as a complete sphenoethmoidal resection, associated with a maxillary antrostomy and a modification of the frontal sinus ostium [19][20][21], different surgical definitions, with no clear criteria by which to comprehensively define their appropriate extent, coexist in the literature, rendering an effective comparison of results among studies especially difficult [22,23]. ...
... While such cases are rare, they represent a persistent, likely growing minority (14)(15)(16), as there is little reason to expect that surgical procedures like colectomy or thyroidectomy occur in different rates between transgender and gender diverse (TGD) patients and non-TGD patients. Among such samples, incomplete information about sex and gender identity limits the ability to adjust for sex-specific confounders, especially with subsamples where recognized sex-specific confounders exist, such as chronic rhinosinusitis (17,18), bladder cancer (19), and colon cancer. (20) While it is notable that some gender diverse people may have received interventions intended to align sex characteristics with gender identity (i.e., hormone Incomplete information about sex and gender identity also limits the ability of surgical quality registries to achieve their intended purpose of improving outcomes and ensuring safety. ...
... Today, the advances in imaging and supermicrosurgical LVB confer an average decrease of 4.1 cm in limb volume and improve the quality-of-life measures in 57-100% of patients. [25][26][27][28][29][30] Despite scientific evidence that LVB can improve subjective and objective outcomes of lymphedema beyond CDT, the marked heterogeneity of practice limits the widespread adoption.6,19,20, [27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42] This narrative review aims to provide an overview of current LVB research, perioperative practices, and outcome measures to highlight essential gaps in the distributed investigation of LVB, which warrant further study and consensus. ...
... Topical intranasal corticosteroids (INCSs) are reported to be effective in improving nasal symptoms and reducing polyp scores and polyp recurrence postoperatively [88]. A meta-analysis indicated that moderate to high evidence of long-term use of INCS resulted in improvement in nasal obstruction via different delivery methods with minimal adverse effects [89]. ...
... 1,2 We highlight 4 papers in this issue that allow us to understand the current state of EHR use, identify unmet needs, provide evidence on their potential to uplift clinical practice and research, and their future potential to improve patient outcomes and address the perpetual problem of the "forgetful health system". [3][4][5][6] Although numerous studies have focused on assessing clinician experience with their EHR systems, few have in parallel obtained the patient's perspective. Meltzer et al, 3 in a survey of health practitioners and their patients from 2 primary care sites, finds discrepancies in experience and attitudes regarding EHR use between patient and clinician. ...
... Furthermore, evidence on the efficacy of ipilimumab and nivolumab, immune checkpoint inhibitors of PD-L1, is conflicting. Gritsch et al. reported a correlation between these agents and longer recurrence-free survival (RFS) and distant metastasis-free survival (DMFS) in MBM patients [29]. In the same year, Guo et al. claimed that PD-1 inhibitors had questionable long-term neurological and cognitive sequelae; the drugs could potentially exacerbate radiation-related necrosis [30]. ...
... The current study assessed the receptivity to MCED testing among a diverse group of providers including staff physicians, residents and fellows, and APPs in primary care. Although there has been a call for incorporating MCED testing into routine cancer screening, there is currently only one clinical assay available-Grail Galleri [10]-and little is known about how this new testing will impact primary care [21]. We found that PCPs are generally receptive to the idea of incorporating MCED testing into their routine practice for cancer screening. ...
... Sclerotherapy, most commonly with the agent sodium tetradecyl sulfate (STS), can be effective as an alternative, although this technique can have serious risks and must be implemented with caution. 22 For all patients requiring operative procedures, we also offer the option of intranasal injection of 0.5 mL of bevacizumab 25 mg/mL in divided doses in the sphenopalatine foramen, posterior bony nasal septum, upper lateral nasal wall, and nasal floor bilaterally. 23 A recent prospective, double-blind RCT comparing this protocol with bipolar cauterization alone showed a clinically significant benefit 4 months after treatment. ...