Ligang Pan's research while affiliated with Beijing Academy of Agriculture and Forestry Sciences and other places

... 采用分子对接手段对抗生素诱导细菌毒性的作 用机制进行探究 [37] . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 ...

... However, other diseases such as neurodegenerative or cardiovascular diseases, among others, have also been targeted in aptamer studies [47][48][49][50][51][52]. In addition to the development of aptamers as therapeutic molecules, other notable approaches include the applications of aptamers as biosensors, through the development of aptamer-based devices and platforms for disease diagnosis [53][54][55][56][57][58][59][60][61][62][63][64], and as molecular tools to deliver therapeutic drugs to specific target cells, as well as to improve access to malignant molecules whose inactivation is desirable [65][66][67][68][69][70]. These applications have driven the significant development of the aptamers-based discipline in recent years. ...

... Carbon dots (CDs) are a rising star in the family of carbon nanoparticles and have garnered extensive attention due to their luminescent properties [1][2][3][4][5][6][7][8]. The past decade has witnessed rapid development in carbon dots (CDs) owing to their diverse sources, including (a) fullerene; (b) graphite; (c) graphene oxide; (d) carbon nanotubes; (e) carbohydrates; etc., as well as significant advantages, such as (a) elemental abundance; (b) hypotoxicity; (c) chemical inertness; (d) outstanding biocompatibility; (e) unique physical properties; (f) affordability; and so on [9][10][11][12][13][14][15][16]. Various methods are commonly used to synthesize fluorescent CDs, such as (a) electrochemical synthesis processes; (b) chemical oxidation methods; (c) hydrothermal cutting strategies; (d) carbonizing organics routes; (e) laser ablation of graphite; (f) ultrasonic methods; (g) hydrothermal; (h) solvothermal; (i) microwaveassisted pyrolysis; etc. [17][18][19][20]. ...

... Food safety is critical to human health. With the improvement in living standards, food safety issues are receiving increased attention [1]. Food safety issues include pathogenic contamination, pesticides and veterinary drug residues, heavy metals and fungal toxin contamination, and illegal and adulterated use of food additives. ...

... Compared to traditional analytical techniques, electrochemical bio sensors exhibit competitive advantages owing to their low-cost instrumentation, automation, and performance comparable to expensive methods entrenched in scienti c practice. Among electrochemical bio sensors, glassy carbon electrode (GCE) [3], screen-printed electrode (SPE) [4], and interdigitated electrode (IDE) [5] have garnered signi cant attention due to their versatility, ease of construction, reliability, and reproducibility. The increasing demand for in-situ and real-time detection of chemical species like biomarkers, pollutants, and drugs has spurred the development of ultra-sensitive, portable electrochemical systems. ...

... For example, it can increase the settling rate of droplets, increase the ratio of fine droplets to reduce drift, decrease evaporation of the liquid in high-temperature and windy conditions, enhance the adhesion rate of the liquid on crop surfaces, and improve the spreading and penetration of the liquid on the crop surface [5][6][7]. Pesticide adjuvants can be classified based on their usage in pesticides, functions, surfactant properties, structural types, molecular sizes, etc. [8][9][10][11][12]. ...

... These fingerprints can vary based on the production processes, raw materials' origins, storage conditions, or adulteration techniques that have affected the levels of metabolites (Medina et al., 2019). In recent years, the authenticity of a variety of food commodities has been developed using omics-based technologies, which are linked to the power of powerful and enormous molecular tools and can help get around the constraints of existing approaches (Balkir et al., 2021;Kafantaris et al., 2020;Zhao et al., 2022). In particular, foodomics uses a variety of omics technologies (genomics, transcriptomics, proteomics, and metabolomics) to offer molecular data on the various expression levels (i.e., gene, transcript, protein, or metabolite), as well as to integrate these data from a systems biology viewpoint (Afzaal et al., 2022 ...

... Several analytical methods have been developed to detect the concentration of paraoxon-ethyl in the environmental matrices based on ultraviolet−visible spectroscopy, 19 surface-enhanced Raman spectroscopy, 20 chemiluminescence, 21 high-performance liquid chromatography−mass spectrometry, 22 gas chromatography−mass spectrometry, 23 quartz crystal microbalance, 24 biosensors, 25,26 and electrochemical methods. 27−29 Although these methods are accurate and trustworthy, their applicability is compromised by their complex pretreatment for sample preparation, overpriced instruments, and the requirement of trained personnel, which make them impractical for daily routine analysis. ...

... Qin et al. 30 established an m-PFC clean-up method for 25 pesticides in six typical matrices, including wheat, spinach, and carrot, and compared it with the QuEChERS method, which stands for quick, easy, cheap, effective, rugged, and safe. Song et al. 31 established a pesticide residue analysis method for 48 pesticides in green tea by combining m-PFC with LC-MS/MS. Currently, existing reports show that the rapid ltration purication technology, known as multiplug ltration clean-up (m-PFC), has been applied as a pretreatment in detecting various pesticide residues in fruits, vegetables, and edible fungi using mass spectrometry analyses such as GC-MS/MS and LC-MS/MS. ...

... China is a major producer of peaches and occupies an important position in the field of economic crops [1,2]. Currently, grafted seedlings are mostly used in peach production, with Amygdalus persica L. and Amygdalus davidiana (Carr.) ...