Léa Campos de Oliveira-da Silva's research while affiliated with Hospital São Vicente de Paulo and other places

Publications (8)

Article
Full-text available
Parasitemia and inflammatory markers are cross-sectionally associated with chronic Chagas cardiomyopathy (CCC) among patients with Trypanosoma cruzi. However, the prospective association of the parasite load and host immune response-related characteristics with CCC (that is, progressors) among T. cruzi seropositive individuals has only been partial...
Article
The aims of this study were to estimate the prevalence of gastrointestinal manifestations among individuals with positive serology for Chagas disease (ChD) and to describe the clinical gastrointestinal manifestations of the disease. A systematic review with meta-analysis was conducted based on the criteria and recommendations of the Preferred Repor...
Article
Full-text available
Background Evaluating the effectiveness of Chagas disease treatment poses challenges due to the lack of biomarkers for disease progression and therapeutic response. In this study, we aimed to assess the clearance of Trypanosoma cruzi ( T. cruzi) parasites in a group of benznidazole (BNZ)-treated chronic Chagas disease patients using high-sensitivit...
Article
Full-text available
Background: Chronic Chagas Cardiomyopathy (CCC) usually develops between 10 and 20 years after the first parasitic infection and is one of the leading causes of end-stage heart failure in Latin America. Despite the great inter-individual variability in CCC susceptibility (only 30% of infected individuals ever present CCC), there are no known predi...
Article
Full-text available
This study aimed to assess the prevalence of non-use of health services in the last year by people with Chagas disease (CD) in an endemic area in Brazil and the contextual and individual factors associated with this non-use. This is a multilevel study that considered contextual and individual data. Contextual data were collected from official publi...
Article
Full-text available
Chagas disease (CD) is recognized by the World Health Organization as one of the thirteen most neglected tropical diseases in the world. Self-perceived health is considered a better predictor of mortality than objective measures of health status, and the context in which one lives influences this predictor. This study aimed to evaluate the prevalen...
Article
Full-text available
Chagas disease (CD) is recognized by the World Health Organization as one of the thirteen most neglected tropical diseases. More than 80% of people affected by CD will not have access to diagnosis and continued treatment, which partly supports the high morbidity and mortality rate. Machine Learning (ML) can identify patterns in data that can be use...
Article
Full-text available
Background: Despite most cases not requiring hospital care, there are limited community-based clinical data on COVID-19. Methods: The Corona São Caetano programme is a primary care initiative providing care to all residents with COVID-19 in São Caetano do Sul, Brazil. It was designed to capture standardised clinical data on community COVID-19 ca...

Citations

... Moreover, no studies have examined the impact of rural and urban environments on the genetic predisposition to cardiometabolic diseases, highlighting a gap in knowledge in LACP. The higher number of nutrigenetic studies in Brazil compared to the other countries could be attributed to several factors including existing data on genetic studies (176)(177)(178)(179)(180)(181), GWAS done mainly in Brazil (182)(183)(184), increased awareness on nutrigenetics in Brazil or more research facilities available in Brazil compared to other LACP. Future gene-lifestyle interaction studies will need to replicate primary research of already studied genetic variants to enable comparison, and to explore the interactions between genetic and other lifestyle factors such as those conditioned by socioeconomic factors and the built environment. ...
... Positive assessments of SH, on the other hand, were discovered to have a protective effect on health behaviors, such as higher levels of exercise and lower levels of smoking and drinking [28]. Based on the fact that satisfaction with health services is associated with positive self-perceptions of health [29], Ferreira AM et al. [30] argued that in smaller cities, people have higher accessibility to health services and increased positive self-perceptions of health due to a closer relationship between health workers and users. ...
... O uso da ML para prever mortes por doenças específicas tem destaque na literatura científica, no entanto, existe pouco material publicado com aplicação na previsão de mortes, conforme afirmado por DC (Ferreira et al., 2022). Essa previsão é importante para subsidiar a alocação de recursos públicos mais eficientes e eficazes, nas áreas cobertas pelo estudo apresentado em (Ferreira et al., 2022) (Ferreira et al., 2022) de forma a contribuir com a avaliação de técnicas para predição de mortes por DC em dois anos. ...
... Forty-nine reports were included in this scoping review. Thirty-two studies were experience reports [16][17][18][19][20]22,23,[25][26][27][28]30,31,35,[38][39][40][41]43,[46][47][48][50][51][52]54,55,57,60,61,63 . We also had three cross-sectional studies 28 60 , a netnography 25 , and four publications had not indicated the type of study 21,24,37,63 . ...