Laura Mateu-Arrom's research while affiliated with Hospital de la Santa Creu i Sant Pau and other places

Publications (10)

Article
Full-text available
Psoriasis is a disease involving the innate and adaptative components of the immune system, and it is triggered by environmental factors in genetically susceptible individuals. However, its physiopathology is not fully understood yet. Recent technological advances, especially in genome and epigenome-wide studies, have provided a better understandin...
Preprint
Full-text available
Psoriasis is considered an immune-mediated disease involving the innate and adaptative immune system triggered by environmental risk factors in genetically susceptible individuals. However, its physiopathology is not fully understood yet. Recent technological advances, specially genome and epigenome-wide studies, have allowed a more sensitive study...
Article
Full-text available
Psoriasis is a chronic systemic inflammatory disease that significatively impairs patients’ quality of life. Biological treatments are highly effective and safe and have led to breakthroughs in the management of patients with moderate-to-severe psoriasis. However, therapeutic response can be unsatisfactory or lost with time, leading to discontinuat...
Article
Introduction and objective The use of onabotulinumtoxin A (BoNT-A) injection in male patients with detrusor overactivity (DO) after stress urinary incontinence (SUI) surgery has been scarcely described. Our aim was to assess results of this treatment in this specific population. Materials and methods Retrospective analysis of men with previous SUI...
Article
Introduction and objective: The use of onabotulinumtoxin A (BoNT-A) injection in male patients with detrusor overactivity (DO) after stress urinary incontinence (SUI) surgery has been scarcely described. Our aim was to assess results of this treatment in this specific population. Materials and methods: Retrospective analysis of men with previous...
Article
Introduction: Although the use of transvaginal mesh (TVM) in the repair of pelvic organ prolapse (POP) has been restricted, there are still some cases in which TVM may be the most appropriate approach. The TVM Surelift® anterior repair surgical technique has not been described previously. Objective: The aim of this study was to describe the surg...

Citations

... The primary risk factor for the onset of psoriatic disease is obesity, which also contributes to the occurrence of psoriatic arthritis. Stress, infection, and medication are the most common trigger factors (1)(2)(3). ...
... In the study investigating the association between the IRF5 risk locus and pathogenic genetic variants in SLE, the intervention effect of regulating IRF5 gene expression using a composite approach was evaluated in monocytes from SLE patients through CRISPRi [11]. The results indicated a close correlation between the rs4728142 allele and increased IRF5 expression, demonstrating the rs4728142 locus as an enhancer regulating IRF5 expression. ...
... 1,4,6,8,10,11 Secondly, we have the pharmacological approach with anticholinergics, antimuscarinics or b3-agonists. 3,4,12 Finally, we have more aggressive therapies such as botulinum toxin infiltration and even surgery. 3,4 All this should always be preceded by a hygienic-dietary strategies to reduce modifiable risk factors. ...
... Mateu Arrom et al.'s study [43] enrolled patients with prior RP and TURP and a history of SUI surgery, including AUS and male sling implantation. At a median follow-up of 49 months, 66.7% of the patients showed subjective improvement in OAB symptoms after injection. ...
... Although TVM can cause bladder damage, lower urinary tract symptoms, pelvic pain, dyspareunia [8,9], and mesh erosion [10,11] as side effects, the USA Food and Drug Administration issued a notification regarding the long-term safety of TVM repair in 2016 [12]. Some TVM kits [13][14][15] are still viable options in Asia and continental Europe for treating symptomatic POP because they offer successful anatomical reconstruction and satisfying subjective outcomes [16]. Nevertheless, the objective therapeutic benefits of TVM, particularly its functional effectiveness in voiding dysfunctions, have been scarcely investigated. ...