L. Whitesell's scientific contributions

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Publications (1)


HSP90 and the chaperoning of cancer
  • Literature Review

January 2005

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42 Reads

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1,783 Citations

Nature Reviews Cancer

L. Whitesell

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S.L. Lindquist
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Citations (1)


... Intriguingly, recent studies unveiled Hsp90's affinity for intrinsically disordered regions (IDRs) of client proteins, highlighting the importance of Hsp90-disordered client interactions 5 . The therapeutic potential of Hsp90 is underscored by its engagement with over 400 cell-signaling regulators, thus designating it as a prime target for anticancer strategies [6][7][8] . ...

Reference:

Structural basis for the dynamic chaperoning of disordered clients by Hsp90
HSP90 and the chaperoning of cancer
  • Citing Article
  • January 2005

Nature Reviews Cancer