January 2005
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42 Reads
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1,783 Citations
Nature Reviews Cancer
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January 2005
·
42 Reads
·
1,783 Citations
Nature Reviews Cancer
... Intriguingly, recent studies unveiled Hsp90's affinity for intrinsically disordered regions (IDRs) of client proteins, highlighting the importance of Hsp90-disordered client interactions 5 . The therapeutic potential of Hsp90 is underscored by its engagement with over 400 cell-signaling regulators, thus designating it as a prime target for anticancer strategies [6][7][8] . ...
January 2005
Nature Reviews Cancer