L D Perricaudet's research while affiliated with Institut de Cancérologie Gustave Roussy and other places
What is this page?
This page lists the scientific contributions of an author, who either does not have a ResearchGate profile, or has not yet added these contributions to their profile.
It was automatically created by ResearchGate to create a record of this author's body of work. We create such pages to advance our goal of creating and maintaining the most comprehensive scientific repository possible. In doing so, we process publicly available (personal) data relating to the author as a member of the scientific community.
If you're a ResearchGate member, you can follow this page to keep up with this author's work.
If you are this author, and you don't want us to display this page anymore, please let us know.
It was automatically created by ResearchGate to create a record of this author's body of work. We create such pages to advance our goal of creating and maintaining the most comprehensive scientific repository possible. In doing so, we process publicly available (personal) data relating to the author as a member of the scientific community.
If you're a ResearchGate member, you can follow this page to keep up with this author's work.
If you are this author, and you don't want us to display this page anymore, please let us know.
Publication (1)
Attempting gene transfer in muscle raises difficult problems: the nuclei of mature muscle fibers do not undergo division, thus excluding strategies involving replicative integration of exogenous DNA. As adenovirus has been reported to be an efficient vector for the transfer of an enzyme encoding gene in mice, we decided to explore its potential for...
Citations
... Thus, this aspect of modified resistance to certain viral infections may spur an interesting insight when theorizing possible skeletal muscle susceptibility to direct SARS-CoV-2 infection. It is rational to suppose that myoblast (15) would be the primary target of COVID-19, as they are actively replicating, as opposed to myofibers and MuSCs (Muscle Stem Cells), which replicate only under specific conditions. This would further contribute to a loss of regenerative abilities of the skeletal muscle in the vicinity of infection, as myoblasts are essential in the musculoskeletal repair, once they differentiate and donate cellular and nuclear components to structure ruptured fibers (16). ...
