Kunal R Sanklecha's scientific contributions

Dalbergia sissoo belonging to family Fabaceae is a widely growing plant and has been reported to possess multiple therapeutic properties like analgesic, anti-inflammatory, analgesic and antipyretic anti-ulcer, antioxidant, anthelmintic, antimicrobial, antidiabetic and is also used to treat syphilis, dysentery, nausea, eye and nose disorder, skin diseases and blood disorder. However, the plant yet has not been fully elucidated for its anti-coagulant property. Hence, in the present investigation an attempt has been made to explore the anticoagulant potential of Dalbergia sissoo bark in comparison with a known standard drug as the positive control and normal saline as the negative control. The anti-coagulant activity of the aqueous and alcoholic extract of Dalbergia sissoo bark may be due to presence of phytochemicals such as flavonoids and phenolic compounds which reveals on preliminary phytochemical screening.

Calotropia gigantea (Asclcpiadacae) is widely growing plant and has been reported to possess multiple therapeutic properties like anti-pyretic, analgesic, anticonvulsant, anxiolytic, sedative, wound healing and antidiabetic. Chemical investigation of Calotropis gigantea report isolation of different type of photochemicals such as flavonoid, glycoside, terpenoid, steroid etc. However its anti thrombotic property has not been yet elucidated. Hence, in the present study we investigated the anti-thrombotic activity of aqueous and alcoholic extract of leaves of Calotropis gigantea in comparison with standard and normal saline as negative control.