Karen KL Chan's research while affiliated with The University of Hong Kong and other places

Publications (4)

Article
Full-text available
Background This study aimed to assess the acceptability and attitudes of women towards human papillomavirus (HPV) self-sampling and compare the effectiveness of two delivery modes utilising face-to-face and online website for cervical cancer screening in Hong Kong. Methods Women aged 30–65 years were invited to participate by distributing the stud...
Article
NUAK family kinase 2 (NUAK2) a member of the AMPK-related serine/threonine kinase family with crucial roles in various cancer cellular processes. The aim of this study was to elucidate the expression and functions of NUAK2 in ovarian cancer while investigating the underlying molecular mechanisms. Analysis of several publicly available databases sug...
Conference Paper
Introduction/Background Ovarian cancer is one of the three major gynecological malignancies, with the highest mortality rate. The field of cuproptosis research has experienced exponential growth in the past year. While numerous studies have established the association between cuproptosis and various cancers, its relevance to ovarian cancer remains...
Article
Ovarian cancer is one of the most severe gynecologic malignancies with high mortality. Although programmed cell death 1 (PD-1) or PD-ligand 1 (PD-L1) immune checkpoint blockade (ICBs) has been used therapeutically in gynecologic cancers and has a clinically significant response in endometrial cancer, the response rate remains poor and has no differ...