Joseph Shelton's research while affiliated with Emory University and other places
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Publications (10)
Purpose
Peer review in the form of chart rounds is a critical component of quality assurance and safety in radiation therapy treatments. Radiation therapy departments have undergone significant changes that impose challenges to meaningful review, including institutional growth and increasing use of virtual environment. We discuss the implementation...
Purpose
The present study aimed to evaluate the associations between the gut microbiome and psychoneurological symptoms (PNS) cluster in women with gynecologic cancers over time.
Methods
In this secondary data analysis, 19 women with cervical and endometrial cancers treated with radiotherapy were followed at pre-treatment, 6–8 weeks, and 6 months...
Introduction: Emerging evidence highlights the role of socioeconomic status (SES) in symptom burden related to cancer treatments. However, its underlying biological mechanisms are not fully understood. Thus, the present study aimed to evaluate the associations between patients’ education, as an indicator of SES, and the gut microbiome with psychone...
Postmenopausal women often suffer from vaginal symptoms associated with atrophic vaginitis. Additionally, gynecologic cancer survivors may live for decades with additional, clinically significant, persistent vaginal toxicities caused by cancer therapies, including pain, dyspareunia, and sexual dysfunction. The vaginal microbiome (VM) has been previ...
Objectives
Gynecologic cancer survivors may live for decades with clinically significant, often persistent symptoms/toxicities including pain, dyspareunia, sexual dysfunction and fatigue. The vaginal microbiome (VM) plays a crucial role in women's health and has been previously associated with vaginal symptoms related to menopause (ie dryness). Our...
The COVID-19 pandemic altered the workplace for medical education. As restrictions ease, the opportunities provided by virtual rotations remain. Radiation Oncology rotations based around virtual participation with patients (consults, follow-ups, and brachytherapy), contouring and reviewing external beam plans, didactics, and unstructured office hou...
p> Background: Women with gynecological cancer (GynCa) undergoing radiation therapy (RT) are at increased risk for acute and long-term sexual dysfunction after treatment. The vaginal microbiome (VM) is the first line of defense against vaginal infection and sexually transmitted diseases. Compositions of VM between women with GynCa receiving RT and...
Background
While the importance of commensal microbes in vaginal health is well appreciated, little is known about the effects of gynecological cancer (GynCa) and radiation therapy (RT) on the vaginal microbiome (VM) of postmenopausal women.
Methods
We studied women with GynCa, pre‐ (N = 65) and post‐RT (N = 25) and a group of healthy controls (N...
Background: Microbial diversity, usually low in healthy women because of Lactobacillus dominance, is associated with vaginal health. No studies, however, have assessed Lactobacillus abundance or microbial diversity in women with gynecologic cancers (GyneCa) treated with radiotherapy (RT).
Aims: This pilot study sought to characterize whether Lactob...
Background: It has been documented that there is a difference in the vaginal microbiome (VM) between Caucasian and African American (AA) women. It is also known that AA women have less of what is considered healthy Lactobacillus in the VM and are more susceptible to abnormal (dysbiotic) VMs, bacterial vaginosis (BV), and infections. Less is known a...
Citations
... Wu et al. found that Delftia genus is enriched in the low-grade squamous intraepithelial lesions (LSIL) and high-grade squamous intraepithelial lesions (HSIL) groups and may be a potential biomarker of CIN progression [14]. A growing number of studies have shown that Delftia was associated with high discomfort or pain following vaginal intercourse [15] and unexplained recurrent pregnancy loss (RPL) [16], which seriously affect both women's physical and mental health. ...
... To date, few research studies investigated the link between vaginal microbiota and anticancer therapies in the frame of gynecological cancers. Tsementzi et al. [127] reported that pelvic radiation negatively affects vaginal microbiota, with several symptoms rising after one year accompanied by an enrichment of opportunistic pathogens [127]. ...
... 41 While previous research has analyzed the practicality of AWAE rotations in other medical specialties, a virtual away rotation specific to anesthesiology has yet to be described. [12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] Although these experiences for surgical specialties may play a vital role in educating students, it remains uncertain whether these experiences can be treated as an audition for a potential seat for an anesthesiology residency position. Considering the significant role that away rotations play in the selection of residents by program directors and the perceived benefits for students, it is crucial to objectively evaluate the advantages and disadvantages of AWAE rotations. ...
... It is not clear if it has a pathologic role. It was later shown by other researchers to be found in the vagina of women with gynecologic cancer [72], and to be associated in large numbers with idiopathic cutaneous ulcers in children treated with azithromycin [73]. ...