Jongho Lee's research while affiliated with Seoul National University and other places
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Publications (5)
Synthetic MRI is a technique that synthesizes contrast‐weighted images from multicontrast MRI data. There have been advances in synthetic MRI since the technique was introduced. Although a number of synthetic MRI methods have been developed for quantifying one or more relaxometric parameters and for generating multiple contrast‐weighted images, thi...
Quantitative susceptibility mapping (QSM) has gained broad interests in the field by extracting biological tissue properties, predominantly myelin, iron and calcium from magnetic resonance imaging (MRI) phase measurements in vivo. Thereby, QSM can reveal pathological changes of these key components in a variety of diseases. QSM requires multiple pr...
Purpose
The peritumoral non-enhancing region (NER) is frequently not removed during the surgical resection of glioblastoma, with most recurrences occurring within the original treatment field. This study determined whether radiomics analysis of the NER can predict local recurrence and overall survival in patients with glioblastoma.
Methods
Preoper...
MR g-ratio, which measures the ratio of the aggregate volume of axons to that of fibers in a voxel, is a potential biomarker for white matter microstructures. In this study, a new approach for acquiring an in-vivo whole human brain g-ratio map is proposed. To estimate the g-ratio, myelin volume fraction and axonal volume fraction are acquired using...
Citations
... This approach offers absolute measurements of tissue microstructure, enhancing the objectivity of disease assessment. Unlike traditional methods, SyMRI allows adjustments of parameters like repetition time, echo time, and inversion time based on mathematical calculations rather than predefined settings (Gulani et al., 2004;Ji et al., 2022). This advancement reduces brain diagnostic study durations to ∼5 min with SyMRI, potentially enhancing throughput and minimizing the need for rescans, while delivering valuable quantitative data (Warntjes et al., 2008). ...
... cadaveric studies [125][126][127], 2 (1.65%) cross-sectional studies [128,129], and finally, only 1 (0.83%) study that presented a case report along with a literature review [130]. The samples included in the studies were distributed across all continents with the exception of Africa; the Asian continent was represented by a total of 56 studies corresponding to 46.28% of the total studies and a sample of 2801 corresponding to 45.00% of the total patients [10,12,16,17,[19][20][21]24,27,[30][31][32]35,36,[39][40][41][42][43][44]46,49,51,53,59,[65][66][67][68][69]71,73,[75][76][77]83,[86][87][88]91,93,94,97,99,101,103,105,107,109,111,116,119,120,122,124], the European continent accounted for a total of 34 (28.10%) studies and 1281 (20.58%) patients [15,18,28,29,45,47,48,50,57,61,63,70,72,74,[78][79][80][81][82]84,85,89,90,95,96,102,104,112,113,117,123,125,130]; North America contributed 28 (23.14%) ...
... thinner axons or lower myelination) that we cannot disentangle here. Future research using large samples with longitudinal data, targeting younger population and/or applying different imaging techniques that can offer deeper insights into the microstructure of white matter tracts (e.g., g-ratio [31]) and reproducibility of the findings reported here are needed. Previous research has shown widespread alterations in white matter tracts in participants with schizophrenia [13], in order to reduce the number of statistical tests and based on the dysconnectivity theory for schizophrenia, we have only included here association tracts innervating the frontal cortex; future research should also offer a wider picture of potential associations between complement PRS and white matter microstructure across the brain. ...