Joan C. Borod's research while affiliated with City University of New York - Queens College and other places

Publications (184)

Chapter
This chapter provides a review of mood, emotional disorders, and emotion processing deficits associated with diseases that cause movement disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, progressive supranuclear palsy, corticobasal degeneration, frontotemporal dementia with parkinsonism, Huntington's disease, e...
Chapter
This handbook is currently in development, with individual articles publishing online in advance of print publication. At this time, we cannot add information about unpublished articles in this handbook, however the table of contents will continue to grow as additional articles pass through the review process and are added to the site. Please note...
Chapter
The purpose of this chapter is to review the various theories of facial emotion lateralization and to provide an examination of the research conducted to date that addresses these theories, drawing upon evidence primarily from behavioral and lesion studies. The chapter focuses on human research, but studies from primates are also considered. The la...
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Given associations between facial movement and voice, the potential of the Lee Silverman Voice Treatment (LSVT) to alleviate decreased facial expressivity, termed hypomimia, in Parkinson's disease (PD) was examined. Fifty-six participants-16 PD participants who underwent LSVT, 12 PD participants who underwent articulation treatment (ARTIC), 17 untr...
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Background: Verbal memory impairment is well documented in type 2 diabetes mellitus (T2DM) but, to date, the neural substrates remain unclear. The present study evaluated verbal memory and ascertained the degree of frontal and temporal lobe involvement in the anticipated verbal memory impairment among adults with T2DM. Method: Forty-six late-mid...
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Consistent with the hypothesis that dopamine is implicated in the processing of salient stimuli relevant to the modification of various behavioral responses, Parkinson's disease is associated with emotional blunting. To address the hypothesis that emotional attention and memory are modulated by dopaminergic neurotransmission in Parkinson's disease,...
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Whereas aging affects cognitive and psychomotor processes negatively, the impact of aging on emotional processing is less clear. Using an "old-new" binary decision task, we ascertained the modulation of response latencies after presentation of neutral and emotional pictures in "young" (M = 27.1 years) and "young-old" adults with a mean age below 60...
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Emotions can affect various aspects of human behavior. The impact of emotions on behavior is traditionally thought to occur at central, cognitive and motor preparation stages. Using EMG to measure the effects of emotion on movement, we found that emotional stimuli differing in valence and arousal elicited highly specific effects on peripheral movem...
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This chapter characterizes the nature of the hemispheric biases in social cognition. This includes both description and discussion of the literature examining the extent of hemispheric specialization in firstly how we identify and interpret the mental states of other people, and secondly how we perceive emotion. Overall, research continues to demon...
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Studies of regional hemispheric asymmetries point to relatively less activity in left frontal and right posterior regions in depression. Anxiety was associated with increased right posterior activity, which may be related to arousal and, in anxious-depressed individuals, offset the posterior asymmetry typically seen in depression. These asymmetries...
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This study was designed to address the issue of whether there is a general processor for the perception of emotion or whether there are separate processors. We examined the relationships among three channels of emotional communication in 100 healthy right-handed adult males and females. The channels were facial, prosodic/intonational, and lexical/v...
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Declarative memory impairment is frequently reported among adults with type 2 diabetes mellitus (T2DM), who also demonstrate hippocampal volume reduction. Our goals were to ascertain whether emotional memory, which is mediated by neural circuits overlapping those of declarative memory, is also affected. In addition we wanted to characterize cerebra...
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Introduction In the 1950s, when behaviorism held sway over psychology, emotion was deemed to be too “subjective” for empirical study. However, the study of emotion has seen something of a renaissance over the past 25 years. The door has opened to a more objective study of emotion, largely due to technological advances and innovative methodologies t...
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This study explored the therapeutic effect of antidepressants in Parkinson's disease (PD) using a meta-analysis. Altogether, 24 placebo-controlled trials qualified for inclusion and revealed that tricyclic antidepressants (TCAs) had a greater antidepressant effect relative to selective serotonin reuptake inhibitors (SSRIs), Qb(1) = 8.87, p < .01, a...
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The aim of this study was to assess the effect of dopaminergic treatment on emotional memory in patients with Parkinson's disease (PD). We tested memory for emotional and neutral visual stimuli in ten non-demented PD patients on and off dopaminergic medication. Patients recalled significantly more emotional items during the off- than on-medication...
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Prosody or speech melody subserves linguistic (e.g., question intonation) and emotional functions in speech communication. Findings from lesion studies and imaging experiments suggest that, depending on function or acoustic stimulus structure, prosodic speech components are differentially processed in the right and left hemispheres. This direct cur...
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Depression is found in about 30%-40% of all patients with Parkinson's disease (PD), but only a small percentage (about 20%) receive treatment. As a consequence, many PD patients suffer with reduced health-related quality of life. To address quality of life in depressed PD patients, we reviewed the literature on the health correlates of depression i...
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The prevalence of apathy was assessed across select cognitive and psychiatric variables in 32 nondemented patients with Parkinson disease (PD) and 29 demographically matched healthy control participants. Apathy is common in PD, although differentiating apathy from motor, cognitive, and/or other neuropsychiatric symptoms can be challenging. Previous...
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Emotional monologues of brain-damaged subjects were examined to determine whether interhemispheric or intrahemispheric differences exist for facial emotional expression. A special feature was the comparison of expressions produced during the initial, middle, and last segments of the monologues. Videotaped emotional and non-emotional monologues from...
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Ventromedial prefrontal cortex (VMPFC) lesions can alter emotional and autonomic responses. In animals, VMPFC activation results in cardiovascular sympathetic inhibition. In humans, VMPFC modulates emotional processing and autonomic response to arousal (e.g. accompanying decision-making). The specific role of the left or right VMPFC in mediating so...
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Parkinson's disease (PD) is a neurodegenerative movement disorder presenting with subcortical pathology and characterized by motor deficits. However, as is frequently reported in the literature, patients with PD can also exhibit cognitive and behavioral (i.e., nonmotor) impairments, cognitive executive deficits and depression being the most promine...
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Converging lines of research suggest that white matter abnormalities may be central to the pathophysiology of schizophrenia. The purpose of this study was to examine regional white matter in the anterior limb of the internal capsules in patients with schizophrenia. The authors obtained high-resolution magnetic resonance imaging in 106 patients with...
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Recovery of emotional functioning following stroke has received limited attention in the neuropsychological literature. By emotional functioning, we refer to a range of processing modes, including perception, expression, experience, and behavior. The aim of the current study was to evaluate the course of prosodic emotional expression over time in i...
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Converging lines of research suggest that white matter abnormalities may be central to the pathophysiology of schizophrenia. The purpose of this study was to examine regional white matter in the anterior limb of the internal capsules in patients with schizophrenia. The authors obtained high-resolution magnetic resonance imaging in 106 patients with...
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A meta-analysis was conducted to examine the effects of the written emotional disclosure paradigm on health outcomes of people with physical or psychiatric disorders. After nine studies were meta-analyzed, it was determined that expressive writing significantly improved health (d .19; p .05). However, this positive relationship (r .10) was not mode...
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The cognitive and behavioral sequelae (i.e., nonmotor profile) of Parkinson's disease (PD), with executive dysfunction and depression being most prominent, have typically been overshadowed due to an emphasis on motor symptomatology. The apparent categorization of PD as a disorder isolated to the dopaminergic system may be a generalization of the di...
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Although improved cognition has been reported in patients with mild Parkinson's disease (PD) following the administration of levodopa, mixed results have been found in moderately-to-severely affected PD patients (MSPD), particularly in studies conducted since 1980. In the present study, 16 MSPD patients were tested on separate days, once following...
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The purpose of this study was to examine changes in the facial expression of emotion across the adult life span. Two positive and two negative emotional expressions were posed by 30 young (21 to 39 years), 30 middle-aged (40 to 59 years), and 30 older (60 to 81 years) healthy, right-handed women. Photographs of the four emotional expressions were r...
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Full-text available
A meta-analysis was conducted to examine the effects of the written emotional disclosure paradigm on health outcomes of people with physical or psychiatric disorders. After nine studies were meta-analyzed, it was determined that expressive writing significantly improved health (d = .19; p < .05). However, this positive relationship (r = .10) was no...
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The cognitive effects of subthalamic nucleus (STN) stimulation in Parkinson's disease (PD) have been examined. However, there are no reported studies that evaluate, by incorporating a disease control group, whether neuropsychological performance in surgical patients changes beyond the variability of the assessment measures. To examine this issue, 1...
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Parkinson's disease is a neurodegenerative hypokinetic movement disorder presenting with subcortical pathology and characterized by motor deficits. However, as is frequently reported in the literature, patients with Parkinson's disease can also exhibit cognitive and behavioral impairments. These impairments may be attributed to dysfunction of multi...
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The purpose of the present retrospective study was to examine the effects of intensive voice therapy on facial expression in Parkinson disease. Parkinson disease (PD) often presents with symptoms that reduce communicative effectiveness on multiple levels, including decreased vocal loudness and reduced facial mobility. Recent advances in voice treat...
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The striatum has recently been implicated as an area that may mediate age-associated cognitive decline because of diminution of volume and functional activity. We used 18F-fluorodeoxyglucose (FDG) with positron emission tomography (PET) and high-resolution magnetic resonance imaging (MRI) to examine the effects of age on striatal glucose metabolic...
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Prosodic expression is an important channel of emotional communication and can be assessed through computerized acoustical analysis. Fundamental frequency (F0) is the most commonly studied acoustic measure and considered the best index of perceived pitch. In this study, we examined two factors that can influence prosodic expression, sex and emotion...
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Does sentence generation and/or stimulus emotionality enhance verbal memory in patients with neurological impairment? This question was addressed by testing 40 patients with unilateral stroke (20 with left-brain and 20 with right-brain damage) and 20 healthy control participants for recall and recognition of 48 target words. During encoding, emotio...
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Despite an ever-increasing literature on language and cognitive recovery after brain injury, there are relatively few investigations about the recovery of emotional processing. The main purpose of this study was to provide a preliminary evaluation of recovery of emotional perception across 3 communication channels in unilateral stroke patients. In...
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This article presents a review of the neural mechanisms underlying emotional processing deficits (EPDs) in individuals with unilateral brain damage. First, key theoretical issues pertaining to the neuropsychology of emotion are presented. These include parameters of emotional processing, the componential approach, emotional domains, and hypotheses...
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The current study examined the effects of age and gender on emotional and nonemotional expression using an experimental word list generation (WLG) task (also referred to in the literature as verbal fluency) from the New York Emotion Battery (Borod, Welkowitz, & Obler, 1992). Subjects were 28 young ( M = 29.6 years), 28 middle-aged (M = 49.8 years),...
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This study used fMRI to examine the response of the amygdala in the evaluation and short-term recognition memory of unpleasant vs. neutral words in nine right-handed healthy adult women. To establish specificity of the amygdala response, we examined the fMRI BOLD signal in one control region (visual cortex). Alternating blocks of unpleasant and neu...
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This technical report and feasibility study propose a standardized method for collecting neuropsychological data in patients undergoing the deep brain stimulation (DBS) procedure. Programs for standardizing motor data collected in studies investigating surgical therapies for Parkinson disease are already widely used (e.g., Core Assessment Program f...
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The relationship between lesion location and neuropsychiatric sequelae in stroke patients has been extensively studied. Emotional disorders associated with right hemisphere stroke include depression, anxiety, anger, and/or mania. Pharmacotherapy, electroconvulsive therapy, and/or psychotherapy are common treatments for these disorders. This article...
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Verbal pragmatic aspects of discourse production were examined in 16 right brain-damaged (RBD), 16 left brain-damaged (LBD), and 16 normal control right-handed adults. The facilitation effect of emotional content, valence hypothesis, and relationship between pragmatics and emotion were evaluated. Participants produced monologues while recollecting...
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This study examined lexical emotional perception in patients with unilateral brain damage. Hypotheses pertaining to laterality and emotion were tested. More specifically, we were interested in whether the right hemisphere is dominant for verbally-presented emotion. In addition, we examined whether emotional content improves the performance of patie...
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The purpose of this study was to consider the effects of valence, motoric direction (i.e., approach/withdrawal), and arousal on the perception of facial emotion in patients with unilateral cortical lesions. We also examined the influence of lesion side, site, and size on emotional perception. Subjects were 30 right-hemisphere-damaged (RHD) and 30 l...
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Objective: This study examined lexical emotional perception in patients with unilateral brain damage. Background: Hypotheses pertaining to laterality and emotion were tested. More specifically, we were interested in whether the right hemisphere is dominant for verbally-presented emotion. In addition, we examined whether emotional content improves t...
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A number of rating systems are available to evaluate emotional communication in a single modality. The main purpose of this study was to develop procedures to train human raters to evaluate posed expressions of emotion across three different channels of communication, i.e., facial, prosodic/intonational, and lexical/verbal. These procedures were us...
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This study examined the psychometric aspects of a verbal pragmatic rating scale. The scale contained six pragmatic features (i.e., Conciseness, Lexical Selection, Quantity, Relevancy, Specificity, and Topic Maintenance) based on Grice's cooperative principles. Fifteen right brain-damaged (RBD), 15 left brain-damaged (LBD), and 16 healthy normal con...
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This study examined facial emotional expressions produced by schizophrenic (SZ), unipolar depressed (UD), and normal control (NC) righthanded adults. Hypotheses regarding right-hemisphere activation in UD and suppression in SZ were addressed, as well as hypotheses about emotion and laterality. Subjects were videotaped while posing positive, neutral...
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The primary purpose of this study was to examine the perception of lexical/verbal emotion across the adult life span. Secondary goals were to examine the contribution of gender and valence (i.e., pleasantness/unpleasantness) to the processing of lexical emotional stimuli. Participants were 28 young (ages 20-39), 28 middle-aged (ages 40-59), and 28...
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In this preliminary study, hemispheric specialization for the experience and expression of emotion was investigated. Subjects were right-brain-damaged (RBD), left-brain-damaged (LBD), and normal control (NC) right-handed adults, carefully matched on demographic and neurological variables. Facial expressions were videotaped while subjects described...
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The purpose of the current study was to examine 49 extant experiments of facial asymmetry during emotional expression in normal adult males and females in regard to gender, valence, and measurement technique. When facial asymmetry was evaluated by trained judges or muscle quantification, facial expressions were left-sided, a finding implicating the...
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The lateralization of emotion perception has been examined using stimuli in both auditory and visual modalities. Studies using dichotic stimuli have generally supported the hypothesis of right-hemisphere dominance for emotion perception, whereas studies of facial and verbal emotion perception have provided evidence for the right-hemisphere and vale...
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Full-text available
Emotional perception was examined in stroke patients across 3 communication channels: facial, prosodic, and lexical. Hemispheric specialization for emotion was tested via right-hemisphere (RH) and valence hypotheses, and relationships among channels were determined. Participants were 11 right-brain-damaged (RBD), 10 left-brain-damaged (LBD), and 15...
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Eleven patients with Parkinson's disease (PD) and predominantly right-sided motor signs, 12 patients with PD and predominantly left-sided signs, and 11 demographically matched healthy controls were compared on tests assessing a range of cognitive and affective functions. Assuming a novel approach, our test battery was composed of measures drawn fro...
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Full-text available
Emotional perception was examined in stroke patients across 3 communication channels: facial, prosodic, and lexical. Hemispheric specialization for emotion was tested via right-hemisphere (RH) and valence hypotheses, and relationships among channels were determined. Participants were 11 right-brain–damaged (RBD), 10 left-brain–damaged (LBD), and 15...

Citations

... Our observed recruitment of activity in the right hemisphere of brocas analogue aligns with a longstanding hypothesis of right-hemispheric preference for affect processing (Borod et al., 1998), potentially reflecting right inferior frontal gyrus/sulcus response to prosodic features of affective vocalisations (Rota et al., 2009). More recent work demonstrates that this network may not be quite so right-sided dominant (Frühholz & Grandjean, 2013), or in fact play a role in specific mediation of other areas during voice recognition tasks (Aglieri et al., 2018). ...
... When there is an emotional arousal, one observes bodily changes resulting from the activities of the brain and the autonomic nervous and endocrine systems. Though the involvement of the brain in emotional discharge is not so well understood, it is noted that emotion involves important interaction between the cortical and subcortical areas (Borod, 2016). Students who go to school need a level of emotional stability for functionality. ...
... Alterations in emotional processing, particularly in recognition of emotions, have been reported for several types of dementia. 9,10 In particular, it is commonly found in patients with behavioral and semantic variants of frontotemporal dementia. 10,11 For AD patients, although it is less prominent, studies have reported their difficulty in recognizing emotional expressions across different types of emotions, where it was most pronounced in recognizing "fear" and the least for "surprised." 12 For DLB, a few studies have suggested deficits in recognizing emotional expressions depending on the type of emotion, for example, diminished recognition of "surprised" faces 13 note that investigations into emotional processing alterations in DLB are still limited. ...
... These findings suggest that there might be an increase in putamen function during the early stages of the illness (Malaspina et al., 2004;Digney et al., 2005;Kumakura et al., 2007). Furthermore, studies indicate that the enlargement of the putamen in SCZ may serve as a diagnostic characteristic, and a greater putamen volume has been linked to positive treatment outcomes (Buchsbaum et al., 2003;Brickman et al., 2006;Kawasaki et al., 2007). Brain regions with significant differences in the ReHo values at baseline between patients with schizophrenia and healthy controls. ...
... (2) Paired Associate Learning Test (PALT): this test is used to evaluate verbal memory, based on semantic cueing [8]. (3) Benton Visual Retention Test (BVRT): for evaluation of visual (perceptual, memory, motor) and visuoconstructive abilities [9]. (4) Token Test: it is used to evaluate receptive language skills [10]. ...
... Repeatedly accessing such phonological associations in response to visual stimuli (i.e., letters) progressively automatizes that process (Ehri, 2005;Ehri & Saltmarsh, 1995;Jones et al., 2018) resulting in the apparent effortlessness of skilled reading. Performance in visual-verbal versions of the paired associate learning task ; an episodic memory paradigm which assesses the ability to accurately bind two distinct items together in memory (Scorpio et al., 2018) and retrieve them later as a single entity (Brockmole & Franconeri, 2009) -has been shown to discriminate typical readers from those with dyslexia (e.g., Jones et al., 2018;Toffalini et al., 2018;Wang, Wass, & Castles, 2017). Paired associate learning performance accounts for unique variance in reading ability, and impairments to the underlying skills appear to result in clinically significant reading difficulties (Litt & Nation, 2014;Wang et al. 2017), supporting the assumption that the task taps abilities that are crucial for skilled reading acquisition. ...
... • • Cambridge Neuropsychological Test Automated Battery (CANTAB®) tests: Motor Screening, Pattern Recognition Memory, Spatial Recognition Memory, Spatial Span; • • Controlled Oral Word Association Test (COWAT; using letters 'F', 'A', 'S') ( Benton and Hamsher, 1976); • • Digit Span Forwards and Backwards ( Wechsler, 1997); • • Rey Auditory-Verbal Learning Test (RAVLT; Rey, 1964); • • Consonant Vowel Consonant Verbal Learning Test (CVCT; Vierck et al., 2015). Pencil-and-paper tests were administered according to standardised instructions. ...
... For each pair, one face was presented above center (x: 680; y: 192), whereas the other was presented below center (x: 680; y: 576). Vertical placements were chosen to minimize the laterality salience of emotional valence in the left visual field, suggesting a right hemisphere advantage (Borod et al., 2001;Brosch et al., 2007). To prevent participants from becoming distracted or losing focus, they were asked to judge the expressions (happy, neutral, or sad) corresponding to the faces (infant or adult) by pressing the number keys 1, 2, and 3 to represent happy, neutral, and sad expressions, respectively, after the image pairs disappeared. ...
... The f o , intensity, and rate measures were calculated from a single sentence from the story read protocol ("Bobby and his mom are picking beets from the garden") using a custom Praat script. The measure f o was calculated only from voiced segments and in semitones to control for f o differences between speakers (Viscovich et al., 2003). The f o mean and f o SD were calculated relative to 1 Hz using the equation 12log (f o ). ...
... Die in diesem Kapitel beschriebenen Patienten wurden in Hinblick auf gestörte allgemeine kognitive Leistungen herausgesucht, auf Teilbereiche der Kognition soll hier nicht eingegangen werden. Vesper et al. (2002), Rodriguez-Oroz et al. (2004), Funkiewiez et al. (2004Funkiewiez et al. ( , 2003, Krack et al. ( ,1998a Morrison et al. (2004) und Hariz et al. (2000 Kumar et al. (1998) keine Angaben zum postoperativen Follow-up machen, Morrison et al. (1998) Operation auf ein betreutes Wohnen angewiesen war, da er nicht mehr fähig war, alleine das Alltagsleben zu bewältigen. ...