Jason H.T. Bates's research while affiliated with University of Vermont and other places

... Ventilator-induced lung injury (VILI) is a common serious complication of mechanical ventilation [24]. In recent years, research has shown that the mechanism of VILI includes not only mechanical stretching but also biological lung injury caused by mechanical stretching [25]. ...

... Therefore, more sensitive validated quantitative CT outcomes are required to detect changes in lung structure over time, as they have the potential reduce the size of samples in clinical trials and provide more incremental assessments of treatment efficacy in PwCF (Rosenow et al., 2015;Kuo et al., 2017b). Hsia et al. (2023) compiled relevant quantitative CT metrics for the assessment of pulmonary diseases. ...

... Recent mechanics-focused (e.g., surface strain, elastance, peak-inspiratory measures) examinations have unearthed both ventilation mode dependencies and non-dependencies [24,73]. Large and small mammalian species mechanics investigations (murine, ovine, and porcine) found equivalent end-inflation pressure and volume measurements whether testing with pressure-or volume-controlled apparatuses [24,27,73]. ...

... 7 Previous studies have confirmed that both incremental and decremental titrations reduce intraoperative shunting; however, only decremental titration improves oxygenation and reduces the airway pressure fluctuations required for pulmonary ventilation. 26 Another recent study suggested that incremental PEEP titration also improves oxygenation 27 and lung gas distribution uniformity in patients undergoing gynecologic laparoscopy. 28 Therefore, patients who underwent OLV during thoracoscopic surgery were included in this study and were studied in conjunction with personalized PEEP titration and PCV-VG. ...

... ARDS is defined as hypoxaemia and respiratory failure secondary to non-cardiogenic pulmonary oedema [3,7]. Studies have shown that pneumonia, ALI and ARDS account for a large proportion of global morbidity and mortality, with pneumonia itself being the most common cause of ARDS [8,9]. The presented cases indicate that acute respiratory failure due to bacterial pneumonia was the immediate cause of death in both patients. ...

... Sin embargo, después de más de un año, hay poco consenso sobre cómo garantizar la continuidad de la educación mientras se intenta evitar la transmisión del virus. En este sentido, Lee et al. (2020) sugieren, basados en datos de Shanghái, que las escuelas pueden reabrir con precauciones y en condiciones de reducción extrema de contacto entre la comunidad. ...

... Eleven studies presented the ages of the participants in time intervals, varying between 18 and 67 years of age [48][49][50][51][52][53][54][55][56][57][58]. Four studies covered the age by reporting only the global mean, varying between x = 23 and x = 29.16 ...

... On the other hand, obesity related central airway collapse can be independent of asthma phenotype [34]. Airway mechanics can be altered in both obesity and/or asthma [35]. BMI has significant effects on all of the lung volumes [36][37][38][39], and the greatest effects were on functional residual capacity and expiratory reserve volume [40]. ...

... The summation of cell fate decisions made by individual cells in a tissue results in an emergent tissue response, such as an expanded, or regressed, microvascular network. Multi-scale computational models allow us to investigate how these different overlapping intracellular and extracellular cues integrate within cells to generate tissue-level outcomes, as well as to isolate how alterations in one cue affects the overall system 55 . Our group has previously developed multi-scale models by combining agent-based modeling (ABM) of multiple cells in a population with logic-based ordinary differential equations modeling of intracellular signaling networks within each simulated cell 56 . ...

... Human breathing is a synergistic process constantly controlled by the autonomic nervous system and may also be deliberately controlled at will, resulting in various breathing patterns 22 . Ashtanga yoga refers to the formal and conventional practice of breath control known as Pranayama, which regulates prana, or the life force. ...