James E. Peacock's research while affiliated with University of Virginia and other places

Publications (4)

Article
An epidemic strain of methicillin-resistant Staphylococcus aureus (MRSA) isolated from patients at the University of Virginia Hospital in Charlottesville (MRSA-Va) was characterized, and virulence properties were compared with those of three clinically significant strains of methicillin-sensitive S. aureus. Unlike most known strains of MRSA, MRSA-V...
Article
Surveillance activities for detection of nosocomial infections at the University of Virginia Hospital (Charlottesville, Va.) and at hospitals participating in the Virginia Statewide Infection Control Program have focused on device-related infections, which potentially are preventable. Surveillance data collected between January 1, 1975, and Decembe...
Article
In March 1978, a strain of methicillin-resistant Staphylococcus aureus was introduced from the community into a university hospital. Within 6 months of admission of the index case, methicillin-resistant S. aureus was isolated from 30 additional patients, 22 of whom were epidemiologically linked by a common phage type (6/47/54/75/83A) and roommate-t...

Citations

... Staphylococcus aureus is a gram-positive bacterium present on the skin and in the digestive tract of humans, and acts as an opportunistic pathogen that causes various diseases such as food poisoning, atopic dermatitis, and pneumonia, which may be fatal in serious cases [1][2][3]. At present, the long-term use of antibiotics has resulted in the development of antibiotic-resistant S. aureus strains that are associated with various clinical issues such as treatment failure and transmission of antibiotics resistance [4,5]. Furthermore, S. aureus forms biofilms which may confer antibiotic resistance, making infections with these strains even more difficult to treat [6]. ...
... The incidence of E.coli and Salmonella was high in CWA both at morning and evening whereas Staphylococcus sps was high on IWT in the morning and evening which might be due to contamination from the animals . The counts of the pathogens were low on GET Table where in pets were examined for short time, but their incidence has been increased evening due to many numbers of patients handling during working time (Wenzel et al., 1981). ...
... On the contrary, there are few studies which had shown that the lethal dose (LD 50 ) of HA-MRSA strains was significantly higher than that for HA-MSSA (Rozgonyi et al., 1984;Kocsis et al., 2010). Moreover, some investigators have revealed no difference between the two populations (Peacock et al., 1981). In the present study, the significant difference observed in survival of MSSA strains in comparison to that of MRSA strains suggested that LA-MRSA were more virulent than LA-MSSA strains. ...