J. Lusztyk's research while affiliated with University of Duisburg-Essen and other places

... 6) using described procedures. [124][125][126][127] Then we carried out the typical iodination of aniline with the acetyl hypoiodite obtained in two conditions, first one without external addition of ammonium acetate, and the second using one equivalent of it. We obtained 51 % in first case and 73 % in second reaction. ...

... To date, there are only a few examples of amino acid derivatives of ferrocenecarboxylic acid in which ordered structural elements that could cause optical activity in the apsorption region of the ferrocene chromophore have been detected. Kraatz and co-workers [102] found a -turn structure in the crystalline state of ferrocenecarboxylic acid substituted with a tripeptide chain (-L-Pro-L-Pro-L-Phe-COOBzl), but did not study its conformation in solution in detail nor did they record its CD spectrum. By introducing a heterochiral peptide chain into the ferrocenecarboxylic acid, Hirao [103] prepared the enantiomeric derivatives Fn-CO-L-Ala-D-Pro-NH-4-Py and Fn-CO-D-Ala-L-Pro-NH-4-Py, which favour a -turnlike structure with the opposite sense of handedness, both in solution and in the solid state. ...

... Simple cyclopropylcarbinyl radicals (type A, Scheme 6a) ring-open very rapidly to form butenyl radicals. 14,15 The rate of the reverse reaction is comparatively very slow, so that these reactions routinely afford ring-opened products as the sole products from reactions. However, when the initial radical carbon is benzylic (type B) 14,15 or is a vinyl radical (type C), 16 then the cyclopropyl ring-opening is readily reversible and cyclic and/or open-chain products can result. ...

... They also found that the MC→SO transition occurs more efficiently in polar solvents, and the excitation of the SO form is the S 0 →S 1 transition which is consistent with the considerations of Schneider et al. Bohne et al. found [19] that in nonpolar media, the X form is in the ground state for a long time (~ 4 μs), after which it almost completely transforms into the MC form. In polar media, the X form in the ground state very fast transforms into the SO form. ...

... Carbenes are active transient intermediates in synthetic organic chemistry and their singlets are capable of abstracting heteroatoms from the heterocycles. [27] The alkyl-substituted carbene abstractions are much more favourable than those of the donor-substituted carbenes. [28] Unsaturated carbenes can cleave aziridines to give corresponding alkenes, since three membered ring systems at their ease form olefins through ring opening. ...

... Shaik et al., 2002). The carbon-centered radical is very short-lived and is rapidly hydroxylated and released from the active site as a metabolite much faster than the radical itself can escape from the hydrophobic enzyme active site (Heur et al., 1989;Bowry et al., 1990;Rota et al., 1997). This scenario reflects the metabolism of PCP by P450 2B6 and accounts for the partition ratio for P450 2B6 inactivation by PCP as being 45 (Jushchyshyn et al., 2003), which suggests that the majority of PCP secondary carbons are oxidized and released from the active site as hydroxylated metabolites (M1 and M2). ...

... Measured [I -] shows no change over time in any of the incubations investigated (Figures 4-6). This is also true for (Ingold et al., 1997;Konya et al., 2000;Heller and Croot, 2010) and ROS-induced oxidation products of CDOM have overlapping absorption peaks. Notably, the SOTS degradation products do not account for the same observations made for the same trend observed in H 2 O 2 observations. ...

... The high instability of alkyldiazonium salts is the main reason why the electrografting of alkyl groups on surfaces by reduction of alkyldiazonium salts has not been achieved until now [14]. Herein, we demonstrate the possibility of attaching alkyl groups on a copper surface by reduction of an acidic or basic aqueous nitrate solution in the presence of an alkylamine. ...

... 8 Although this process is thermally reversible in non-nucleophilic solvents and under inert atmosphere, bisketenes undergo irreversible reactions with H 2 O in usual biological media, thereby preventing ring closure to recover the initial squaramide motif. 9 This photobehavior prompted us to design a new class of squaramido-type ligands for new Pt(II) photocages. These new ligands may stabilize the Pt(II) center, preventing or substantially reducing its activity. ...

... [26][27][28][29][30] Although effective in the formation of α-X (X = O, N, S) divalent carbon species, 1,3,4-oxadiazolines were only evidenced to give alkylidene carbenes trapped as pyridinium ylides under laser flash photolysis (LFP) at 308 nm. [31][32][33] When exposed to UV light, non-stabilized diazo compounds are however generated. [34][35][36] While the first photolysis report dates back to 1968, 34 it was only recently that the Ley group proposed their application as diazo precursors in UV light-induced aryl-alkyl cross-coupling 37 and C-H functionalization reactions of aldehydes. ...