Herbert G. Starr's scientific contributions
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Publications (3)
A 2½-year-old girl ingested one or more lindane pellets. Irritability followed by grand mal seizures occurred. On supportive therapy she recovered within 24 hours. Serum levels were relatively high initially but dropped rapidly. Considerable amounts of pesticide were present in the initial stool sample, suggesting that induced emesis and catharsis...
The case of a 64-year-old pesticide formulator is presented. Despite the fact that the patient had no more exposure to dieldrin and several other organochlorine pesticides than his occupational associates, and that he used protective clothing, he, nonetheless, developed relatively high levels of these chemicals in his blood and tissues. The high le...
Citations
... Moreover, the simultaneous lessening of melanin and β-HCH, as well as the unaffected accumulation of β-HCH in lightly pigmented melanocytes and non-pigmented cells, suggests a possible preferential localization of this organochloride in melanin-loaded melanosomes. Adsorption of HCH isomers has been extensively demonstrated in human serum, adipose tissue, brain, kidney, muscle, sebum, and placenta, following inhalation, oral and dermal exposure [48][49][50]. In the general population as well as in occupational workers, the accumulation of β-HCH assumed a linear increase over the time of exposure [51]. ...
... Moreover, the simultaneous lessening of melanin and β -HCH as well as the unaffected accumulation of β -HCH in lightly pigmented melanocytes and non-pigmented cells suggests a possible preferred localization of this organochloride in melanin-loaded melanosome. Adsorption of HCH isomers has been extensively demonstrated in human serum, adipose tissue, brain, kidney, muscle, sebum, and placenta following inhalation, and oral and dermal exposure [47][48][49]. In the general population as well as in occupational workers samples the accumulation of β-HCH assumed a linear increase over the time of exposure [50]. ...
... 125 .inally, a higher blood concentration of a pesticide was seen in a formulator as compared to his coworkers, which was attributable to the presence of scleroderma in the worker with the high blood levels. 126 Hyperproliferation of the stratum corneum, as in psoriasis, exfoliative dermatitis, or ichtyosis, also results in increased permeability of the skin. 127,128 Rapidly generated stratum corneum, while thicker, is usually a poorer barrier. ...
