Garima Rathi's research while affiliated with Delhi Public School Allahabad and other places
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Publications (9)
Breast cancer is a carcinoma of mammary glands, which starts off as abnormal proliferation of ductal cells. This could, then, become either benign tumours or metastatic carcinomas. It is one of the most common causes of deaths because of cancer, and is one of the most common types of cancer in women in the whole world. India along with the US and C...
OVID-19 is a serious viral infection that struck the world in December 2019 starting from Wuhan in China, spreading subsequently to all over the world. The disease has baffled scientists and doctors worldwide in terms of its presentation, behaviour, and treatment options till now. A low mortality rate is the only relief we get so far from COVID-19...
COVID-19 is a serious viral infection that struck the world in December 2019 starting from Wuhan in China, spreading subsequently to all over the world. The disease has baffled scientists and doctors worldwide in terms of its presentation, behaviour, and treatment options till now. A low mortality rate is the only relief we get so far from COVID-19...
Breast cancer is a carcinoma of mammary glands, which starts off as abnormal proliferation of ductal cells. This could, then, become either benign tumours or metastatic carcinomas. It is one of the most common causes of deaths because of cancer, and is one of the most common types of cancer in women in the whole world. India along with the US and C...
Epigenetic silencing of tumor suppressor genes in cancers can lead to unusual consequences in various perspectives of the disease. DNA repair genes, help to repair the malicious adducts formed by carcinogens which disrupts the cell cycle. MGMT is such a DNA repair gene, which encodes the protein O6 methylguanine DNA methyltransferase, which repairs...
One of the mechanisms for epigenetic silencing of tumor suppressor genes is hypermethylation of cytosine residue at CpG islands at their promoter region that contributes to malignant progression of tumor. Therefore, activation of tumor suppressor genes that have been silenced by promoter methylation is considered to be very attractive molecular tar...
Citations
... MSCs may also assist in the prevention or shortage of the manifestations of long-COVID-19 syndrome [38]. Currently, numerous clinical trials utilizing either autologous, allogeneic, adult-, or fetal-derived MSCs against SARS-CoV-2 are underway with promising results [39][40][41]. However, to achieve the best outcome through the administration of MSCs, different factors that may induce variability in their immunoregulatory properties must be determined. ...
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... Similarly, the substance inhibited Twist via the p38MAPK pathway, exhibiting apoptotic activity in MCF-7 cells. 78,79 Similarly, it was also observed that MCF-7 cells exhibited anti-proliferative and apoptotic activities through Go/G1-phase arrest and decreased survivin expression. Combining Quercetin with ascorbic acid (vitamin C) in combination with prescription drugs like doxorubicin or paclitaxel significantly improved the anti-cancer activities of the treatments in breast cancer cells by reducing the S and Go/G1 phases. ...
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