G F Aldred's research while affiliated with University of Melbourne and other places
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Publications (13)
To define measures of assessing success and subsequent ways to improve excimer laser treatment of astigmatism.
We studied 97 eyes of 79 patients, followed for 12 months, that underwent photorefractive keratectomy (PRK) for myopia and astigmatism with a VISX 20/20 excimer laser. Preoperative spherical equivalent refraction at the corneal plane was b...
To describe variation in surgical and patient management and to assess their effect on 12-month outcomes of photorefractive keratectomy (PRK).
The following variations in surgical/patient management related to PRK were observed and assessed: treatment based on cycloplegic refraction, administration of anesthesia, marking of visual axis, diameter of...
The incidence and correlations of undercorrection were studied for 1 year after excimer laser surgery for myopia or myuopic astigmatism.
A consecutive series of 645 eyes of 440 patients were studied. Eyes were examined preoperatively and at 1, 3, 6, and 12 months after surgery. The parameters evaluated were visual acuity, refraction, and corneal cl...
To evaluate the surgically induced astigmatism (SIA) 1 year after excimer laser photorefractive astigmatic keratectomy (PARK) and photorefractive keratectomy (PRK).
Royal Victorian Ear and Eye Hospital, Melbourne, Australia.
This study comprised 333 PARK patients and 155 PRK patients treated with a VISX 20/20 excimer laser and followed prospectivel...
Purpose:
To examine the effect of hormone use, pregnancy and menopausal status on clinical outcomes following excimer laser surgery for myopia and myopic astigmatism.
Methods:
Participants comprised all female patients of the Melbourne Excimer Laser Group (MELG). A standardised surgical protocol was followed by the 27 MELG members, using the Vis...
Purpose: To evaluate the surgically induced astigmatism (SIA) 1 year after excimer laser photorefractive astigmatic keratectomy (PARK) and photorefractive keratectomy (PRK).Setting: Royal Victorian Ear and Eye Hospital, Melbourne, Australia.Methods: This study comprised 333 PARK patients and 155 PRK patients treated with a VISX 20/20 excimer laser...
To examine prospectively the efficacy and safety of photorefractive keratectomy and photoastigmatic refractive keratectomy.
We treated 645 eyes (440 patients) with a VisX Twenty/Twenty excimer laser and followed them up for 12 months.
The percentage of eyes with myopia between -5.01 and -10.00 diopters spherical equivalent within 1 and 2 diopters o...
To prospectively examine the predictability of excimer laser photorefractive keratectomy and photoastigmatic refractive keratectomy for myopia that ranged from -1 to -18 diopters (D).
Patients were treated with an excimer laser and followed up prospectively for 12 months. Low myopia was treated in one ablation zone (6.0 mm), high myopia in two abla...
To study the incidence and associations of overcorrection after excimer laser treatment of myopia and myopic astigmatism.
The study cohort consisted of 645 patients who had photorefractive or photoastigmatic refractive keratectomy done by an excimer laser during a 2-year period. Patients were assessed 1,3,6, and 12 months postoperatively. The varia...
To determine the risk factors for undercorrection of myopia after photorefractive keratectomy and to evaluate the efficacy and safety of retreatment.
A VISX Twenty/Twenty excimer laser was used to treat myopia and myopic astigmatism of up to -15.00 diopters (spherical equivalent) at the corneal plane. Retreatments were performed primarily for under...
BACKGROUND: Although researchers have reported that postoperative pain in patients undergoing excimer laser photorefractive keratectomy (PRK) surgery is common in the first 24 hours after excimer surgery, factors associated with increased postoperative pain have not been reported. The purpose of this study was to prospectively document self-reporte...
Although researchers have reported that postoperative pain in patients undergoing excimer laser photorefractive keratectomy (PRK) surgery is common in the first 24 hours after excimer surgery, factors associated with increased postoperative pain have not been reported. The purpose of this study was to prospectively document self-reported pain follo...
To evaluate prospectively the efficacy and safety of excimer laser photorefractive keratectomy in the treatment of myopia and myopic astigmatism.
Up to 15 diopters (D) of myopia with or without astigmatism of less than 6 D was treated with an excimer laser (VISX Twenty/Twenty). One hundred fifty procedures have been followed up for more than 12 mon...
Citations
... 35,37,42,54,55 Pain is known to subside when re-epithelialization of the cornea is completed. 68,70 After PRK, the corneal surface is known to regenerate in 3 to 4 days. Bandage contact lenses reduce epithelial defect size considerably on the third postoperative day compared with the first postoperative day with maximum benefits observed with lotrafilcon B (41) among the selected BCLs for the study. ...
... [1][2] Reports of the visual outcome of the correction of myopic astigmatism (PARK) have also been encouraging. [3][4][5][6][7][8][9][10][11][12] However, the major proportion of visual improvement has been the result of improving the patients spherical refraction. 13 If one examines the changes in induced astigmatism, it appears the success in treating astigmatism may not approach that achieved when treating spherical myopia. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/277233332703232-1443108985110_Q64/Noel-Alpins-Am.jpg)
... But low predictability, refractive stability and high complication rate were reported from these methods [4][5][6]. 193_nm excimer laser is used successfully in treatment of myopia and astigmatism [7,8]. This laser, generates a smooth ablation on peripheral corneal stroma, could be used in hypermetropia treatment with its promising results [9]. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/272793434587142-1442050431198_Q64/Grant-Snibson.jpg)
... Retreatment options include LASIK, repeat PRK, phototherapeutic keratectomy (PTK), and possibly even collagen cross-linking [6,7]. While PRK enhancement for residual refractive error after PRK has been studied, little investigation has occurred over the last 2 decades regarding the safety and outcomes of PRK enhancement after PRK, despite significant advances in techniques and technologies [8][9][10][11][12]. ...
... Subjects with preoperative subjective refractive error of more than SE -6.0 D had 5.29 times more risk of ametropia following transPRK (P=0.010). This finding was in line with some previous studies agreeing that retreatment rate or ametropia after LASIK and PRK was associated with higher degree of initial correction [11,[14][15]17,[22][23] . This might happen due to the less predictability of nomogram in higher correction [15] . ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/11431281085921377-1663977657303_Q64/Rasik-Vajpayee.jpg)
... 15 Second, the results of refractive surgery are less predictable in subjects with high myopia. 25 Other demographic patterns have been noted in European-derived populations with refractive errors. Age has been highly correlated with the prevalence of different refractive errors. ...
... In these cases, PRK is the preferred treatment. However, high myopia corrected with PRK often leads to haze formation in a high percentage of cases with subsequent loss of vision [39,40]. ...
... Additionally, in case of refractive errors resulted from thin corneas, laser in situ keratomileusis (LASIK) cannot be performed for patients with mildly topographic irregularities and epithelial basement membrane disease, but PRK can be performed safely [7,8]. Nevertheless, corneal haze, epithelial healing irregularity, and pain accompany as most notable adverse effects of PRK [9,10]. PRK is a well-established technique with a low complication rate performed for more than 20 years [11]. ...
... Indeed, estrogen treatment has been linked to the induction of photophobia, blurred vision, foreign body sensation, heightened sensitivity, contact lens intolerance and variations in corneal thickness, edema and curvature [19,26,27,29,[61][62][63][64][65]. These effects may account for why hormone replacement therapy in postmenopausal women may reduce visual acuity [66], and why oral contraceptive use in premenopausal women may increase corneal hydration, sensitivity and contact lens discomfort [27,67,68], and lead to an elevated blink rate [69]. ...
... Subjects with preoperative subjective refractive error of more than SE -6.0 D had 5.29 times more risk of ametropia following transPRK (P=0.010). This finding was in line with some previous studies agreeing that retreatment rate or ametropia after LASIK and PRK was associated with higher degree of initial correction [11,[14][15]17,[22][23] . This might happen due to the less predictability of nomogram in higher correction [15] . ...
