Fandou Kong's research while affiliated with First Affiliated Hospital of China Medical University and other places
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Publications (8)
Background
Ovarian clear cell carcinoma (OCCC) is one of the special histologic subtypes of ovarian cancer. This study aimed to construct and validate log odds of positive lymph nodes (LODDS)-based nomograms for predicting the overall survival (OS) and cancer-specific survival (CSS) in patients with OCCC.
Methods
Patients who underwent surgical tr...
The vaginal microbiota plays an important role in the health of the female reproductive tract and is closely associated with various pregnancy outcomes and sexually transmitted diseases. Plenty of internal and external factors have strong influence on the changes in a woman's vaginal microbiome. However, the effect of a high-altitude on female vagi...
Ovarian clear-cell cancer is a rare subtype of epithelial ovarian cancer with unique clinical and biological features. Despite optimal cytoreductive surgery and platinum-based chemotherapy being the standard of care, most patients experience drug resistance and a poor prognosis. Therefore, novel therapeutic approaches have been developed, including...
Background
Previous studies have not established potential causal associations between coffee and caffeine consumption in endometrial cancer (EC) and its subgroups. Therefore, we used a two-sample MR method to assess the causal association between coffee and caffeine consumption and EC risk. We also evaluated the association between these genetical...
Background
MetS is associated with greater morbidity and mortality in relation to a number of malignancies, but its association with ovarian cancer remains contested. The present study was a systematic review and meta-analysis of case-control and cohort studies examining the association between MetS and ovarian cancer risk.
Methods
The study was r...
Background
High-grade squamous intraepithelial lesion (HSIL) is a disease that is closely related to the development of cervical cancer. In clinical work, cold knife conization and a loop electrosurgical excision procedure (LEEP) are often selected for diagnosis and treatment.
Objective
In this paper, we aimed to discuss additional cuts, a common...
Objective: We aimed at discussing additional cuts, a common problem in cervical conization. Whether the doctor’s choice of additional cuts in conization surgery could reduce the occurrence of positive cone margin. Design: A retrospective study. Setting: First Affiliated Hospital of Dalian Medical University (Dalian, China). Population: 965 patients...
Objective: To investigate the relationship between serum magnesium and metabolic syndrome (MetS) and serum metabolic parameters in endometrial cancer (EC) patients.
Patients and methods: A retrospective study was designed to collect medical records of 291 patients diagnosed with EC from July 2016 to May 2021. Independent samples t-test, ANOVA, and...
Citations
... Recently, new clinical treatment methods have GUO et al. been developed, including immune checkpoint blockade therapy, targeted angiogenesis therapy, the use of ARID1A synthesis for lethal interactions, and targeting liver cell nucleus factor 1 β New therapies such as ferroptosis bring great hope to ovarian cancer patients. 26 Compared to imaging recognition of distant metastases and staging diagnosis, model provides a new approach. This algorithm is from a statistical perspective, using an RF model and introducing relevant variables to determine the probability of distant metastasis. ...
... Since the relationship between dietary factors and CRC has not been explored by any genetic instruments, we hypothesized there was a causative association of CRC with dietary factors. Similar to randomized controlled trials, the Mendelian randomization (MR) study is a novel research method that uses single-nucleotide polymorphisms (SNPs) as instrumental variables (IVs) to infer causal relationships between risk factors and health outcomes (15). This research methodology draws upon Mendel's second law of genetics. ...
... MetS is associated with a 4-fold increase in coronary artery disease events [3] and a 1.2-fold increase in overall mortality [4]. Additionally, the prevalence of some cancers [5][6][7][8] higher in people with MetS compared to the general population. Given the high prevalence of MetS and its health effects, it is critical to understand the factors that influence its development. ...
