Ethel Leonor Noia Maciel's research while affiliated with Ministério da Saúde do Brasil and other places
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Publications (153)
Background: International migration is a global phenomenon with significant implications on the health–disease process due to exposures along transit routes and local/destination epidemiological indicators. We aimed to analyze the transmission and spread of tuberculosis among international migrants and refugees from a spatiotemporal perspective and...
A dengue evoluiu de uma doença restrita a alguns países para um grave problema global de saúde pública, atingindo mais de 120 países nos últimos anos. No Brasil, após sua reintrodução em 1981, o país enfrentou diversas epidemias, com mais de 16 milhões de casos registrados até o momento. Em 2023, sob a vigência do fenômeno climático El Niño registr...
Este boletim tem como finalidade apresentar informações estratégicas destinadas a orientar as ações de saúde pública em hanseníase no âmbito nacional.
The emergence and continued geographic expansion of arboviruses and the growing number of infected people have highlighted the need to develop and improve multiplex methods for rapid and specific detection of pathogens. Sequencing technologies are promising tools that can help in the laboratory diagnosis of conditions that share common symptoms, su...
Facing the decline in vaccine coverage observed since 2016, the new Brazilian government committed to reversing this scenario. To achieve this, the Federal Government launched the National Vaccination Movement and the 'Health with Science' platform to combat vaccine misinformation, promoted Microplanning, providing tools for decision-making at the...
Background
One of the three main targets of the World Health Organization (WHO) End TB Strategy (2015-2035) is that no tuberculosis (TB) patients or their households face catastrophic costs (defined as exceeding 20% of the annual household income) because of the disease. Our study seeks to determine, as a baseline, the magnitude and main drivers of...
Resumo Objetivo: analisar a prevalência de tuberculose, coronavírus, condições crônicas e vulnerabilidades entre migrantes e refugiados no Brasil. Método: trata-se de estudo transversal, do tipo inquérito eletrônico, realizado com migrantes internacionais durante a pandemia de COVID-19. Para a análise, aplicou-se estatística descritiva, com cálculo...
Resumen Objetivo: analizar la prevalencia de tuberculosis, coronavirus, condiciones crónicas y vulnerabilidades en inmigrantes y refugiados en Brasil. Método: se trata de un estudio transversal, del tipo encuesta electrónica, realizado con migrantes internacionales durante la pandemia de COVID-19. Para el análisis se aplicó estadística descriptiva,...
Objective:
to analyze the prevalence of tuberculosis, coronavirus, chronic conditions and vulnerabilities among migrants and refugees in Brazil.
Method:
this is a cross-sectional study of the electronic survey type conducted with international migrants during the COVID-19 pandemic. Descriptive statistics was applied for the analysis, with calcul...
Objective
to analyze Primary Health Care professionals’ perceptions about the access of people with pulmonary tuberculosis to government social support and income transfer programs.
Methods
multicenter/qualitative study, carried out in Family Health Units in four Brazilian capitals: Belém/Pará, Campo Grande/Mato Grosso do Sul, Recife/Pernambuco an...
Objective
to analyze Primary Health Care professionals’ perceptions about the access of people with pulmonary tuberculosis to government social support and income transfer programs.
Methods
multicenter/qualitative study, carried out in Family Health Units in four Brazilian capitals: Belém/Pará, Campo Grande/Mato Grosso do Sul, Recife/Pernambuco an...
Resumen Objetivo: describir el proceso de implementación subnacional de la certificación de eliminación de la transmisión vertical (TV) de sífilis y/o VIH, barreras, oportunidades y desafíos. Métodos: en 2022, se evaluaron indicadores del último año completo para la meta de impacto y de los dos últimos años para las de proceso en los sistemas de in...
Resumo Objetivo: descrever o processo de implantação subnacional da certificação da eliminação da transmissão vertical de HIV e/ou sífilis, suas principais barreiras, desafios e oportunidades. Métodos: em 2022, foram avaliados indicadores do último ano completo para meta de impacto, e dos dois últimos anos completos para metas de processo, disponív...
Objective
to describe the subnational implementation process of the certification for elimination of mother-to-child transmission of HIV and/or syphilis, its main barriers, challenges and opportunities.
Methods
in 2022, indicators from the last full year for impact targets and the last two full years for process targets, available in national info...
Background
Eliminating mother-to-child transmission (MTCT) of HIV, hepatitis B, and syphilis is a challenge in Brazil. Many policies have been implemented since 1986, but important gaps remain. This study aimed to describe the trends of MTCT in Brazil and evaluate the gaps and perspectives in this scenario.
Methods
This is a descriptive study cond...
https://cealag.com.br/pubdigital/icv_2023/#p=1
Relatório Final - Inquérito de cobertura e hesitação vacinal nas capitais brasileiras, Distrito Federal e em 12 municípios do interior, em crianças nascidas em 2017-2018 e residentes nas áreas urbanas
Instituições participantes: Departamento de Saúde Coletiva da Faculdade de Ciências Médicas da Santa...
The emergence and reemergence of mosquito-borne diseases in Brazil such as yellow fever, zika, chikungunya, and dengue have had serious impacts on public health. Concerns have been raised due to the rapid dissemination of the chikungunya virus across the country since its first detection in 2014 in Northeast Brazil. In this work, we carried out on-...
Este material consolida informações sobre importantes sistemas de informação em saúde que abrangem dados sobre diferentes aspectos da linha da vida dos cidadãos brasileiros e que estão sob gestão do Departamento de Análise Epidemiológica e Vigilância de Doenças Não Transmissíveis (Daent), ligado à SVSA. Logo, serão consideradas, neste material, bas...
Objective: The national vaccination coverage survey on full vaccination at 12 and 24 months of age was carried out to investigate drops in coverage as of 2016. Methods: A sample of 37,836 live births from the 2017 or 2018 cohorts living in capital cities, the Federal District, and 12 inner cities with 100 thousand inhabitants were followed for the...
La planificación y ejecución del Plan Nacional de Inmunizaciones contra el COVID-19 en Brasil se han desarrollado en un escenario de crisis sanitaria y política, afectado por intensas discusiones y desacuerdos entre las áreas técnica y de gestión del gobierno. Así, a pesar de la exitosa experiencia del Programa Nacional de Inmunizaciones brasileño...
Objetivo
Identificar a percepção dos gestores de saúde sobre as ações adotadas e os desafios encontrados no enfrentamento de HIV e sífilis em mulheres venezuelanas migrantes no Brasil.
Métodos
Este estudo descritivo-exploratório, de abordagem qualitativa, foi realizado de janeiro a março de 2021 nos municípios de Boa Vista (estado de Roraima) e Ma...
Com grande importância epidemiológica mundial, a doença de Chagas é caracterizada como uma doença tropical negligenciada, a qual acomete populações vulneráveis devido ao contexto socioeconômico de pobreza, tornando-se uma questão desafiadora para a garantia dos princípios constitucionais do Sistema Único de Saúde (SUS).
A infecção por Trypanosoma c...
The emergence and reemergence of mosquito-borne diseases in Brazil such as Yellow Fever, Zika, Chikungunya, and Dengue have had serious impacts on public health. Concerns have been raised due to the rapid dissemination of the chikungunya virus (CHIKV) across the country since its first detection in 2014 in Northeast Brazil. Faced with this scenario...
Introdução: o Brasil demorou a implementar uma política de testagem ampliada para COVID-19 no qual pode ter afetado o acesso da população mais vulnerável aos serviços de testagem. Objetivo: analisar os fatores associados à realização de testes moleculares para o diagnóstico da COVID-19. Método: estudo transversal de dados secundários do painel COVI...
Esta publicação é resultado da ação conjunta de trabalhadores da saúde de todo o País, atestando a importância do preenchimento adequado dos formulários, repasse oportuno das bases de dados e tratamento rigoroso de cada variável presente nos sistemas de informação em saúde.
Objetivo
Descrever a percepção de mulheres venezuelanas sobre o acesso aos serviços de saúde, ao diagnóstico e ao tratamento de HIV/aids e sífilis no Brasil.
Métodos
Trata-se de um estudo descritivo e exploratório, com abordagem qualitativa, realizado no período de fevereiro a maio de 2021 nos municípios de Manaus, estado do Amazonas, e Boa Vista,...
BACKGROUND: Among Brazilian initiatives to scale up TB preventive therapy (TPT) are the adoption of the 3HP regimen (12 weekly doses of rifapentine and isoniazid [INH]) in 2021 and the implementation in 2018 of the TPT surveillance information system. Since then, 63% of the 76,000 eligible individuals notified completed TPT. Recommended regimens in...
Introduction:
It is essential to strengthen the treatment of latent tuberculosis infection (LTBI) to break the chain of transmission. The drug used worldwide for the treatment of LTBI is Isoniazid. A clinical trial conducted in Brazil has demonstrated the bioequivalence of Isoniazid in the 300 mg formulation with 3 tablets in the 100 mg formulatio...
Introdução: O impacto econômico da Tuberculose (TB) leva ao empobrecimento das famílias em países de baixa e média renda, mesmo o tratamento sendo ofertado sem custos. Um dos objetivos da Organização Mundial de Saúde é que nenhum domicílio afetado pela TB sofra com custos catastróficos da doença. Objetivos: O presente estudo teve como objetivo aval...
Objective
to understand the primary social network map as a technology for the approach to people with pulmonary tuberculosis.
Method
a qualitative study, grounded on the Social Network theoretical-methodological framework and carried out from January to February 2020 with 32 individuals diagnosed with pulmonary tuberculosis at Basic Health Units...
Objective
to understand the primary social network map as a technology for the approach to people with pulmonary tuberculosis.
Method
a qualitative study, grounded on the Social Network theoretical-methodological framework and carried out from January to February 2020 with 32 individuals diagnosed with pulmonary tuberculosis at Basic Health Units...
This article aims to analyze the profile of people with disabilities among the cases notified by the COVID-19 panel of Espírito Santo and the possible associations with the positive result of the COVID-19 test. Descriptive cross-sectional study among people with disabilities with positive and negative tests for the diagnosis of COVID-19. Associatio...
Objective:
To analyze SARS-CoV-2 seroprevalence and association of sociodemographic and clinical aspects in the state of Espírito Santo, Brazil.
Methods:
This was a serial cross-sectional study carried out in four phases, using households as the unit of analysis, from May to June 2020. Eleven municipalities were surveyed, with a sample of 4,500...
Background
In 2019, tuberculosis incidence and mortality in Brazil were 46 and 3·3 per 100 000 population, respectively, and the country has reported rising tuberculosis case rates since 2016, following an economic crisis beginning in mid-2014. We aimed to estimate the number of excess tuberculosis cases and deaths during the recession period, and...
This article aims to analyze the profile of people with disabilities among the cases notified by the COVID-19 panel of Espírito Santo and the possible associations with the positive result of the COVID-19 test. Descriptive cross-sectional study among people with disabilities with positive and negative tests for the diagnosis of COVID-19. Associatio...
Objectives: to characterize school-aged children, adolescents, and young people’s profile and their associations with positive COVID-19 test results. Methods: an observational and descriptive study of secondary data from the COVID-19 Panel in Espírito Santo State in February to August 2020. People suspected of COVID-19, in the 0–19-years old age gr...
Several vaccines against COVID-19 are now available, based on different techniques and made by different laboratories spread around the world. With the roll out of the vaccination process in an advanced stage in many countries, and the reduced hospitalization risk by the Omicron relative to Delta variant infection, despite the higher transmission r...
Objectives:
to analyze government social initiatives aimed at people with tuberculosis and the possibilities of access to government social programs and income transfers through the perception of tuberculosis program managers.
Methods:
descriptive, qualitative study with 19 managers from Belém, Recife, Campo Grande, and Rio de Janeiro, Brazil. T...
Background:
Non-compliance with latent tuberculosis infection (LTBI) treatment is a reality. The objective of this study was to develop and validate an mobile device application for monitoring the treatment of LTBI.
Methods:
We defined the requirements, elaborated on the application's conceptual map, generated implementation and prototyping alte...
Resumo O presente texto trata de refletir sobre a campanha de vacinação contra COVID-19 no Brasil à luz da consideração das evidências científicas no processo de tomada de decisão. O Brasil possui um dos maiores e mais completos programas de vacinação do mundo, o Programa Nacional de Imunizações (PNI). Infelizmente, no contexto atual, com as interf...
O objetivo foi estimar o percentual de pessoas privadas de liberdade no Espírito Santo, Brasil, infectados com o SARS-CoV-2 e apresentar os fatores associados ao resultado positivo. Trata-se de um inquérito sorológico, realizado entre os dias 31 de agosto e 4 de setembro de 2020, nas 34 unidades prisionais do estado. Realizou-se uma entrevista e te...
Objetivo: Estimar a prevalência de infecção por SARS-CoV-2 entre trabalhadores do sistema prisional do Espírito Santo, Brasil, no período agosto-setembro de 2020. Métodos: Inquérito em amostra estratificada, mediante entrevistas e testes sorológicos para SARS-CoV-2. Resultados: Nos 986 pesquisados, a prevalência deinfecção por SARS-CoV-2 foi de 11,...
According to the World Health Organization (WHO), latent tuberculosis occurs through latent infection by Mycobacterium tuberculosis without evidence of active tuberculosis (TB) symptoms. As patients don’t develop the same symptoms as active TB, the treatment is abandoned before the end, as it lasts about six months. This leads to significant treatm...
A partir da reemergência da febre amarela em 2014/2015, o Brasil registrou nos anos sequentes sua maior epidemia de febre amarela das últimas décadas, atingindo principalmente a região sudeste. A febre amarela, doença viral hemorrágica, é causada por um flavivírus, transmitido por mosquitos silvestres (Haemagogus; Sabethes). Na ocorrência do ciclo...
Este livro trata-se de um catálogo de fontes com uma parte considerável do levantamento da pesquisa realizada durante os dois primeiros anos de pandemia: são manifestos, orientações, trabalhos acadêmicos, livros, guias, manuais de orientação e documentos legais que vocês poderão consultar acessando o link de cada arquivo. Nele também constam materi...
Objective
to understand the collective thinking and action of health workers in relation to Latent Tuberculosis Infection and its treatment with Isoniazid.
Method
qualitative study with 22 health professionals from four cities in Brazil and the Federal District. Data collection occurred through a semi-structured group interview in March 2019, with...
Objective
to understand the collective thinking and action of health workers in relation to Latent Tuberculosis Infection and its treatment with Isoniazid.
Method
qualitative study with 22 health professionals from four cities in Brazil and the Federal District. Data collection occurred through a semi-structured group interview in March 2019, with...
Background:
One of the most recent concerns of this pandemic regards the role of schools reopening in disease transmission, as well as the impact of keeping schools closed. While school reopening seems critical for the education and mental health of children, adolescents, and adults, so far the literature has not systematically reached a consensus...
Background
The provision of care and monitoring of health are essential for indigenous Venezuelans from the Warao ethnic group, who are at risk of decimation.
Objective
Analyze a Local Action Plan (LAP) to promote access to the health system of indigenous Venezuelans from the Warao ethnic group (IVWEG) in Manaus, Brazil.
Method
A mixed-methods st...
Objectives:
to estimate the prevalence of SARS-CoV-2 infection in residents of the Greater Vitória region living in subnormal and non-subnormal agglomerates, and to compare sociodemographic and clinical characteristics of total residents (infected and not infected with SARS-CoV-2) between them.
Methods:
Population-based prevalence study conducte...
O objetivo foi analisar a difusão dos casos de febre amarela no tempo e no espaço, na epidemia de 2017, no Estado do Espírito Santo, Brasil. Estudo observacional ecológico, com análise espacial da difusão dos casos de febre amarela. Para o georreferenciamento das informações e a análise espacial, utilizou-se a malha digital do Estado do Espírito Sa...
Resumo O objetivo deste artigo é avaliar a associação entre estar privado de liberdade ou em situação de rua e o insucesso no desfecho dos casos de tuberculose diagnosticados no Brasil em 2015. Foram estudados casos de tuberculose na população privada de liberdade e em situação de rua do Brasil em 2015, por análise descritiva e regressão logística...
Resumo Objetivo: Analisar aspectos sociodemográficos e clínicos autorreferidos entre indivíduos de 2 a 22 anos de idade e possíveis associações com infecção por SARS-CoV-2 no Espírito Santo, Brasil. Métodos: Estudo transversal seriado de base populacional, realizado de maio a junho de 2020. Avaliou-se o percentual de positividade para COVID-19, por...
RESUMO: Objetivo: Apresentar um estudo de prevalência em presídios e estimar o percentual de pessoas privadas de liberdade, profissionais de saúde e agentes penitenciários infectados com o SARS-CoV-2 no Espírito Santo (ES). Métodos: Tratou-se de um estudo de prevalência com amostragem realizada em 34 unidades prisionais no ES, estratificadas entre...
Resumo Objetivo avaliar o impacto econômico domiciliar do adoecimento pela tuberculose no Brasil. Método pesquisa transversal multicêntrica de 2016 a 2018, em cinco capitais do Brasil, em pacientes diagnosticados com tuberculose. Os custos totais foram a soma dos custos diretos e indiretos incorridos antes e durante o diagnóstico e tratamento. A re...
Introduction:
We investigated the association of self-reported comorbidities with fatality risk among individuals infected with Coronavirus disease 2019 (COVID-19) in Espírito Santo State, Brazil.
Methods:
We included 212,620 individuals, ≥30 years old. The data were obtained from the COVID-19 panel. Kaplan-Meier curves and Cox regression model...
Resumo Objetivo Analisar a associação entre determinantes sociais e morbidades para os desfechos de internação, internação em unidade de terapia intensiva e óbito por COVID-19 no Espírito Santo, Brasil. Métodos Estudo transversal, com dados secundários de casos confirmados de COVID-19 notificados no Sistema de Informação de Agravos de Notificação....
Resumo O processo de elaboração do Plano de Imunização contra Covid-19 no Brasil se iniciou tardiamente e contou com a participação de especialistas incluindo o grupo técnico responsável pela definição de grupos prioritários para a vacinação. Este processo foi permeado de indefinições entre o Governo Federal e pesquisadores e, finalmente, no dia 20...
Objectives:
Healthcare workers (HCWs) have a high risk of acquiring tuberculosis infection (TBI). However, annual testing is resource-consuming. We aimed to develop a predictive model to identify HCWs best targeted for TBI screening.
Methodology:
We conducted a secondary analysis of previously published results of 708 HCWs working in primary car...
Objetivos: estimar prevalência de infecção pelo SARS-CoV-2 em residentes na região da Grande Vitória moradores de aglomerados subnormais e não subnormais; e, comparar características sociodemográficas e clínicas dos residentes totais (infectados e não infectados com o SARS-CoV-2), entre esses aglomerados. Método: Estudo de prevalência de base popul...
Background
Tuberculosis (TB) in migrants is of concern to health authorities worldwide and is even more critical in Brazil, considering the country´s size and long land borders. The aim of the study was to identify critical areas in Brazil for migrants diagnosed with TB and to describe the temporal trend in this phenomenon in recent years.
Methods...
Objetivo: Analisar aspectos sociodemográficos e clínicos autorreferidos entre indivíduos de 2 a 22 anos de idade e possíveis associações com infecção por SARS-CoV-2 no Espírito Santo, Brasil. Métodos: Estudo transversal seriado de base populacional, realizado de maio a junho de 2020. Avaliou-se o percentual de positividade para COVID-19, por teste...
Background
Migrants are a high priority group for TB control measures due to their high exposure to risk factors such as poverty and social vulnerability. The study aimed to identify factors associated with latent TB among international migrants living in four Brazilian state capitals. This was a cross-sectional study conducted in September and Oct...
Resumo Objetivo: Avaliar o impacto dos custos catastróficos no desfecho desfavorável do tratamento da tuberculose. Métodos: Estudo de coorte prospectiva, realizado em cinco capitais de estados brasileiros (Manaus, Recife, Vitória, Campo Grande e Porto Alegre) no período de junho de 2016 a julho de 2018. Empregou-se regressão logística para calcular...
A formação de vínculo entre famílias de crianças com Síndrome Congênita do Zika (SCZ) e profissionais de saúde é condição sine qua non para o desenvolvimento das crianças afetadas. O estudo objetiva compreender a perspectiva de mães de crianças com SCZ acerca da abordagem profissional e da formação de vínculos no processo de cuidado em saúde durant...
Resumo Objetivo: analisar como a proteção da saúde dos trabalhadores da Atenção Básica à Saúde (ABS) é abordada nos planos de contingência das capitais brasileiras e do Distrito Federal (DF) para o enfrentamento da pandemia de COVID-19. Métodos: estudo descritivo, de base documental, com caráter analítico-reflexivo, que tomou como objeto de análise...
Esta obra é composta por 21 capítulos, elaborados por 54 autores, os quais se debruçaram sobre os múltiplos temas que perpassam as atividades daqueles(as) que se dedicam a tornar as universidades e as instituições de ensino tecnológico em ambientes amistosos para a diversidade humana, em especial para alunos, docentes e técnicos com deficiência. Es...
Objetivos: analisar o perfil epidemiológico das pessoas com deficiência infectadas com o SARS-CoV-2 notificadas no Espírito Santo. Método: Estudo comparativo entre as pessoas com deficiência com testes positivos e negativos para o diagnóstico de COVID-19. Foram realizadas associações dos resultados do teste e as variáveis epidemiológicas e clínicas...
Objective:
To assess the association between tuberculosis determinants and performance of directly observed treatment (DOT) under different levels of Family Health Strategy (FHS) coverage in Brazil.
Methods:
This was a cross-sectional study using data on tuberculosis cases notified between 2014 and 2016 on the Notifiable Health Conditions Informat...
Objetivo. Analisar a associação entre determinantes da tuberculose e a realização do tratamento diretamente observado (TDO), sob diferentes níveis de cobertura da Estratégia Saúde da Família (ESF) no Brasil. Métodos. Estudo transversal, com dados dos casos de tuberculose notificados no Sistema de Informação de Agravos de Notificação entre 2014 e 20...
Citations
... En dengue se han desarrollado pruebas inmunocromatográficas capaces de dar un diagnóstico con una sensibilidad y especificidad aceptable, en este sentido son poco útiles para la atención clínica pruebas que solo tienen pocos laboratorios y requiere el envío de la muestra lejos del lugar de atención, estas pruebas serian útiles para la vigilancia pero no necesariamente para modificar o aclarar dudas en la atención. En este sentido es importante el desarrollo y despliegue de pruebas rápidas inmunocromatográficas de diagnóstico primario y de emergencia en brotes epidémicos, como ya se podrían mostrar avances en pruebas rápidas que permiten diagnosticar el dengue (4) así como los serotipos circulantes y también complementando el componente laboratorial con el enfoque de diagnóstico sindrómico (5) . Debiendo también desarrollar plataformas que incluyan el diagnóstico de varias etiologías con este mismo enfoque de síndrome febril. ...
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... depending on the methodology of human capital (S2 and S3 Tables) or the output approach. CC for TB treatment in Colombia are similar to the Brazilian estimates [28] and higher than in Fiji, the other countries with medium to high income level that finished the survey. Additionally, Colombia's value for CC due to TB was inferior to estimates taken in Burkina Faso, the Democratic Republic of Congo, Myanmar, Vietnam, Laos, Ghana, Mongolia, and others [10,27,29]. ...
... 14 Although Brazil began implementing HIV prevention and control policies as early as 1986, the uneven economic development levels among its regions have resulted in the policies not achieving the desired effectiveness. 15 Furthermore, the sustainability of free drugs is affected by the resources and capabilities of various parties such as the government, medical systems and funders. [16][17][18] For example, the Indian government began nationwide promotion of tuberculosis preventive therapy specifically targeting PLHIV in 2017. ...
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... The 2016 epidemic predominantly saw the circulation of the CHIKV-Asian genotype. By contrast, in 2023, there was a discernible change to the ECSA genotype, which has become prevalent in the Americas [9][10][11]. Accompanying this lineage replacement was a noticeable increase in case numbers, indicating a significant epidemiological shift. ...
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... For the year 2020, these rates were 9.9 in the North Region, 9.4 in the Northeast, 7.9 in the Midwest, 7.6 in the Southeast and 6.8/1,000 LB in the South Region. 2 The state of Rio de Janeiro demonstrated the highest rates of infant and neonatal mortality among the other states that compose the Southeast Region in 2020: 14.3 and 8.8 per 1000 LB, respectively. 2 The causes of neonatal death are mostly avoidable, with the presence of qualified healthcare during the prenatal and delivery period, and for the newborn. ...
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... Several articles focused on the barriers that migrants from Venezuela faced in different settings. Mocelin and colleagues highlighted how language, out-of-pocket expenses relating to accessing care, and COVID-19 challenges acted as barriers to access HIV/AIDS and syphilis treatment in Brazil (21). On the other hand, the Brazilian universal health system and other health policies acted as facilitators to access care. ...
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... However, there has been a disproportionate number of cases among gay men and other men who have sex with men (MSM), leading the WHO and some national governments to issue specific recommendations for this group (Macedo & Maciel, 2023;Sousa et al., 2022;Vallée, 2023;World Health Organization, 2023). Notably, official guidelines highlight sexual behavior, advocating for a reduction in practices that involve multiple partners, such as group sex and chemsex (Şahin et al., 2023;Sousa et al., 2022). ...
... This proportion is lower than TPT non-completion rates in other studies. (5,16,17,18,19,20,21,22,23) After adjustment for other potential variables, Individuals between the ages of 15 and 34 were found to be factor associated with TPT discontinuation. This nding is consistent with a study in Portugal.(6) ...
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... Rifampin and isoniazid, used for LTBI treatment, can cause adverse effects such as hepatotoxicity and peripheral neuropathy (Jonas et al., 2023;Kim et al., 2023). It is important to ensure that the drugs used for treatment are safe for patients and that effective methods are developed for each step of LTBI testing and treatment (Yang et al., 2023;Cola et al., 2023). Additionally, there is a need for research on drug susceptibility for available pharmacotherapy. ...
... In logistical terms, CC due to TB estimates did not consider several vulnerable groups like homeless, incarcerated, and people younger than 18 years (the latter usually included in National TB patient cost surveys following WHO design). These groups are difficult to follow-up and legal and national ethic review board constraints did not allow their inclusion in this study, as occurred in other Latin-American countries [41]. On the other hand, some municipalities presented limitations in finding sufficient cases which met the criteria to be included in the study. ...
