Eleanor C. Adams's research while affiliated with Harvard Medical School and other places

... A definite connective tissue layer lies the cavity and the blood vessels are numerous and become sinusoidal. [6,7] At this stage it can be seen as a yellowish projection from the surface of the ovary occupying about half the volume of ovary. The mature stage of the corpus luteum coincides with the pre-menstrual or luteal phase of the endometrium. ...

... these ribonucleoprotein particles through the nuclear pores into the cytoplasm of the oocyte in Monodelphis, some similar material has been observed in the cytoplasm, most often close to the nucleus. These findings corroborate those arrived at in the guinea pig, hamster and mouse (Adams & Hertig, 1964;Weakley, 1969;1971;Takeuchi et al. 1984Takeuchi et al. , 1986. ...

... Treatment of oocytes with CCCP, an ionophore which dissipates the mitochondrial membrane potential (Heytler, 1963), led to the loss of TMRE, confirming its specificity (Fig. S2A). In human and Xenopus oocytes, the majority of the mitochondria was present within the Balbiani body, as previously reported (Boke et al., 2016;Hertig and Adams, 1967) (Fig. 1G, S2B-C). Indeed, the center of the mitochondrial mass was mostly located inside the Balbiani body in human and Xenopus oocytes ( Fig. S2B-C). ...

... Recent studies, however, also suggest that direct intercellular communication involving exchange of intracellular signals through the cell membrane-associated gap junctions may play a significant role in this tissue (Grazul-Bilska et al., 1994;Khan-Dawood et al., 1995a;Pate, 1996). Gap junctions have been recognized by ultrastructural studies as well as immunohistochemistry, using antibodies specific for gap junction-forming proteins, the connexins, in both human and baboon corpora lutea ( Figure 6) (Adams and Hertig, 1969;Fukushima, 1977;Khan-Dawood et al., 1996c). The connexins, which are transmembrane proteins, form a channel between cells, called the connexon. ...

... Other top human embryologists of the early 1900s-CR Bardeen, RR Bensley, EA Read, SH Gage, RE Sheldon, HH Donaldson, EH Dunn, and GL Streetercollaborated on a joint paper in the Journal (Bardeen et al., 1908). Subsequent notable papers are authored by Frederic T. Lewis (Lewis, 1909(Lewis, , 1912, Clarence L. Turner in 1920(Turner, 1920, HE Jordan (Jordan, 1918), Leslie B. Arey (Arey, 1925), Ernst De Vries (De Vries, 1927), Edward A. Boyden (Boyden, 1931;Boyden, 1932;Boyden andRigler, 1934), Peter Gruenwald (Gruenwald, 1940), G. Gordon Robinson and S. Lea O'Neill (Gordon Robinson, 1948), Ian M. Monie (Monie, 1949), Eileen M. Otis and Robert Brent (Otis, 1954), Donald G. McKay et al. (McKay et al., 1955, 1956, Ronan O'Rahilly and Fabiola M€ uller (O'Rahilly, 1984), Richard P. Dickey and Raymond F. Gasser (Dickey and Gasser, 1993) Robert J. Tomanek (Tomanek, 2016), and Timothy D. Smith et al. (Smith et al., 2017). As a side bar, Ian Monie taught me embryology while I was a postdoctoral fellow at the University of California, San Francisco in the early 1980s. ...

... These observations were backed up by electron microscope (EM) data showing distinct enrichment of ribosomes at the germ granule periphery, and presence of polyribosomes at this location ( Figures 3D and 3E). Glycogen particles that were previously detected in germ cells [39][40][41][42] , were also found in the granules, where they could be well distinguished from ribosomes by their size and staining intensity ( Figure S3D). Interestingly, the EM images also revealed the presence of rough endoplasmatic reticulum (ER) membrane at the circumference of germ granules ( Figures 3D and 3E), further supporting the notion that the periphery of the organelle represents a site of translation. ...

... Our study firstly reported the mutations in the exon of ATP1A1 are related to the reproductive of goose. Histochemical localization of ATPase activity sites in the ovary has been studied in several mammalian species, such as guinea pigs, rabbits, and humans (Adams et al., 1966;Koudstaal and J€ obsis, 1974). Sangha et al. (1991) reported the histological changes of general ATPase activity during follicles formation, corpus luteum formation and regression in the rat ovary. ...

... The article by Kalbfuss & Gönczy [1] allowed us to propose a hypothetical explanation for this phenomenon. In cow oocytes, centrioles are completely absent, as in all previously studied mammals [5,6]; they are eliminated during the process of oogenesis; the mechanism of this elimination is not fully understood. ...

... The steroidogenic cells of the theca interna develop into the theca lutein or small luteal cells. In human, the latter remain located in the periphery of the corpus luteum, whereas in ruminants the small luteal cells intersperse between the large luteal cells (252,253). In rodents it is still not clear if thecal-derived luteal cells exist. ...

... Sources of cholesterol for progesterone synthesis include endocytosis of cholesterol-rich low-or high-density lipoproteins (LDL and HDL, respectively), as well as de novo synthesis of cholesterol (19). Another source of cholesterol is found in cytoplasmic lipid droplets, which are abundant in luteal cells (20)(21)(22). These cytoplasmic organelles are surrounded by a phospholipid monolayer that coats an inner neutral lipid core consisting of cholesterol esters and triglycerides (22,23). ...